Explore top 2026 4 Star Hotels in St. Ann
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Top St. Ann 4 Star hotels
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $117 total per night from Mar 9 to Mar 10
$117 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,236 reviews)
Zero complaints! Enjoyed our stay and will stay again!
Reviewed on Feb 15, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Feb 27 to Feb 28
$176 total
Feb 27 - Feb 28
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.4/10 Very Good! (4,013 reviews)
The first room we got was not the cleanliest and was really rundown. So we called down to the front desk and got a second room, which was much better and you could tell was remodeled in the bathroom. Smelled clean, looked clean unlike first room.
Reviewed on Feb 11, 2026
Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $152 total per night from Mar 1 to Mar 2
$152 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,001 reviews)
Hotel is beautiful and restaurants met our needs perfectly. Clean, attractive, and spacious room. Bathroom was spotless and well-appointed. The round table and chairs were a great convenience. Beds exceptionally comfortable. Good lighting, lots of outlets and charging spots. I am a happy customer, ...
Reviewed on Feb 11, 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 22 to Feb 23
$162 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,602 reviews)
Everything was superlative. Staff, hotel, room, pool.
Reviewed on Feb 11, 2026
The Cheshire
6300 Clayton Rd Richmond Heights MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $170 total per night from Feb 25 to Feb 26
$170 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.6/10 Excellent! (1,001 reviews)
The theme of the entire hotel is wonderful. The staff is fantastic. The Fox and Hound Tavern is the most quaint aesthetics ever! Breakfastvis great. Clean rooms. Loved the themed rooms and read a little of the book portraying our themed lady of the court! Great place to stay!
Reviewed on Feb 7, 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Feb 27 to Feb 28
$143 total
Feb 27 - Feb 28
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,064 reviews)
Everything was excellent.
Reviewed on Feb 3, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $141 total per night from Feb 22 to Feb 23
$141 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
8.8/10 Excellent! (1,051 reviews)
Very clean, even friendlier.
Reviewed on Feb 12, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Feb 17 to Feb 18
$177 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (1,121 reviews)
Great views, friendly staff, clean rooms, everything you need is right there for you. Room service was convenient and walking distance to fun restaurants and city life
Reviewed on Feb 9, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Feb 22 to Feb 23
$148 total
Feb 22 - Feb 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,001 reviews)
The room was amazing! Very spacious & the beds were very comfortable. The bathtub was perfect for soaking after a long day of sports. Let’s all talk about Orlando…the best valet/staff member there. He was so friendly & helpful. We will for sure be staying here again.
Reviewed on Feb 11, 2026
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $215 total per night from Mar 9 to Mar 10
$215 total
Mar 9 - Mar 10
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,001 reviews)
Room was clean, plenty of space
Reviewed on Feb 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels St. Ann
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in St. Ann 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in St. Ann will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in St. Ann, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent St. Ann hotel reviews by fellow wanderers
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Zero complaints! Enjoyed our stay and will stay again!"
A verified traveler stayed at Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
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