Explore top 2026 4 Star Hotels in St. Ann

Name: Ameristar Casino Resort and Spa
Price range: $205 total
Rating: 8.4

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Top St. Ann 4 Star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

$97 nightly

$115 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,166 reviews)

Great stay. Superb staff. Rooms were beautiful except bathroom very dated and the corners were not very clean

Reviewed on Dec 25, 2025

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

$129 nightly

$152 total

Jan 2 - Jan 3

Total with taxes and fees

This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

8.4/10 Very Good! (4,023 reviews)

Staff was supper nice and it all went so smooth.

Reviewed on Dec 26, 2025

Hilton St. Louis Frontenac

1335 S Lindbergh Blvd Frontenac MO

Fully refundableReserve now, pay when you stay

$130 nightly

$152 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.6/10 Excellent! (1,002 reviews)

Great room, great amenities!

Reviewed on Dec 17, 2025

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

$148 nightly

$173 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,510 reviews)

The entire hotel was fantastic. Beautifully decorated, so much to see. The art gallery was fantastic, the servers at the bar were friendly and phenomenal and just made for a great evening. The food was fantastic. Every inch of the building was well styled and the room was fantastic. Can’t wait to ...

Reviewed on Dec 22, 2025

The Cheshire

6300 Clayton Rd Richmond Heights MO

Fully refundableReserve now, pay when you stay

$117 nightly

$139 total

Jan 13 - Jan 14

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

8.6/10 Excellent! (1,000 reviews)

Very friendly staff!

Reviewed on Dec 22, 2025

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO

Fully refundableReserve now, pay when you stay

$122 nightly

$143 total

Jan 16 - Jan 17

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

8.4/10 Very Good! (1,062 reviews)

Clean rooms and friendly, accommodating staff.

Reviewed on Dec 24, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3550 Samuel Sheppard Drive St. Louis MO

Fully refundableReserve now, pay when you stay

$114 nightly

$134 total

Jan 5 - Jan 6

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...

8.8/10 Excellent! (1,039 reviews)

Great property.

Reviewed on Dec 22, 2025

Live by Loews - St.Louis

799 Clark ave St. Louis MO

Fully refundableReserve now, pay when you stay

$149 nightly

$177 total

Jan 4 - Jan 5

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (1,105 reviews)

Great view from room. Excellent service from staff.

Reviewed on Dec 29, 2025

The Westin St. Louis

811 Spruce St St. Louis MO

$135 nightly

$158 total

Feb 1 - Feb 2

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,000 reviews)

Everything was perfect

Reviewed on Dec 16, 2025

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

$175 nightly

$205 total

Jan 11 - Jan 12

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.4/10 Very Good! (1,011 reviews)

From check-in to check-out the staff was extremely professional, friendly, and courteous. The room was fabulous. It was clean and so spacious. A sunken sitting area was an added bonus. We had a view of the river and the bridge. My expectations were definitely exceeded. The only thing that was frustrating ...

Reviewed on Dec 28, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels St. Ann

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in St. Ann 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in St. Ann will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in St. Ann, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.