Explore top 2026 4 Star Hotels in St. Ann
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Top St. Ann 4 Star hotels
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $165 total per night from Jul 17 to Jul 18
$165 total
Jul 17 - Jul 18
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,236 reviews)
"Lobby restrooms were in terrible shape with wallpaper falling off the wall. The roof top balcony was nothing like the picture and wasn’t clean or maintained. The parking garage scenario was a catastrophe. People were waiting for over an hour to get there vehicles from being forced to valet park only ..."
Reviewed on Jul 13, 2026
Moonrise Hotel
6177 Delmar Blvd St. Louis MO
$157 nightly
The price is $186 total per night from Jul 16 to Jul 17
$186 total
Jul 16 - Jul 17
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9/10 Wonderful! (2,014 reviews)
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Reviewed on Jul 10, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$198 nightly
The price is $234 total per night from Aug 2 to Aug 3
$234 total
Aug 2 - Aug 3
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,026 reviews)
"I love staying at the Chase. Check in was easy. My room was clean and quiet. The furnishings were updated and the room was very comfortable. The staff is always friendly and helpful. It’s a great property."
Reviewed on Jul 12, 2026
Hilton St. Louis Frontenac
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Jul 17 to Jul 18
$117 total
Jul 17 - Jul 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,008 reviews)
"We got a junior suite which was located in the Clayton building. It was clean and comfortable. Not extravagant, but nice. We did open the couch bed for my kids and the cover was dirty and there were no blankets or pillows. The front desk had someone to our room within about 20 minutes to put a brand ..."
Reviewed on Jul 12, 2026
St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
$156 nightly
The price is $186 total per night from Jul 20 to Jul 21
$186 total
Jul 20 - Jul 21
Total with taxes and fees
This luxury hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free WiFi. ...
8.8/10 Excellent! (1,014 reviews)
"loved the entire atmosphere and how central the location was to things we wanted to do. Will definitely be staying again!"
Reviewed on Jul 12, 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jul 31 to Aug 1
$143 total
Jul 31 - Aug 1
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,121 reviews)
"They did not come clean my room the first two days. I had to call the front desk. The front desk staff was very nasty when I checked in."
Reviewed on Jul 13, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Jul 17 to Jul 18
$189 total
Jul 17 - Jul 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,247 reviews)
"The stay at Live by Loews - St. Louis, Missouri was great. Super convenient to walk right across the street and arrive at Busch Stadium🏟️. The room was nice and clean with a great view and the dining experience at Clark & Bourbon was amazing both for dinner last night and breakfast this morning. ..."
Reviewed on Jul 13, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $164 total per night from Jul 19 to Jul 20
$164 total
Jul 19 - Jul 20
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,007 reviews)
"We have stayed here before and had the same delayed check-in experience. The lobby is full of guests waiting for a room an hour or more past check in time of 4pm. People have plans, cranky kids, need to change etc and this is unacceptable. Many properties have adapted the “no daily room service unless ..."
Reviewed on Jul 12, 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Aug 9 to Aug 10
$173 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,965 reviews)
"The hotel room was beautiful and very comfortable! The restaurant was amazing, museum was awesome and location was close to everything!"
Reviewed on Jul 12, 2026
River City Casino & Hotel
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $126 total per night from Aug 2 to Aug 3
$126 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
9.2/10 Wonderful! (1,665 reviews)
"Great staff and location. Went to a Cardinals game and tour of the arch."
Reviewed on Jul 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels St. Ann
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in St. Ann 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in St. Ann will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in St. Ann, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent St. Ann hotel reviews by fellow wanderers
Pear Tree Inn St. Louis Airport
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Great location. Very close to airport and rental cars. Shuttle was convenient and helpful."
A verified traveler stayed at Pear Tree Inn St. Louis Airport
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