Explore top 2026 4 Star Hotels in St. Ann
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Top St. Ann 4 Star hotels
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from May 3 to May 4
$173 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,731 reviews)
We had a double queen room and one bed didn’t have a comforter. We checked in with 4 adults but only had 3 towels in the bathroom. On the second day we asked for a comforter for the second bed and extra towels and then never received them. Elevators are a pain in the behind also. We did love all ...
Reviewed on Apr 6, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $160 total per night from May 8 to May 9
$160 total
May 8 - May 9
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.6/10 Excellent! (4,005 reviews)
Nice stay at an older downtown hotel. Was in walking distance of most attractions we were in town for. Very quiet even though there were several middle and high school girls volleyball teams in town for a tournament. Would definitely stay there again.
Reviewed on Apr 6, 2026
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 8 to May 9
$143 total
May 8 - May 9
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,080 reviews)
Great staff. Accomodated my husbands request to face the airport runway. Clean rooms with comfortable bed and large tv.
Reviewed on Apr 5, 2026
River City Casino & Hotel
777 River City Casino Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $130 total per night from Apr 13 to Apr 14
$130 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...
9/10 Wonderful! (1,514 reviews)
Good time
Reviewed on Apr 6, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $158 total per night from Apr 19 to Apr 20
$158 total
Apr 19 - Apr 20
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,006 reviews)
This hotel was amazing! I forgot a phone charger & one of the maintenance guys ran out to his truck to get me one. The rooms were amazing. The bathroom was like a spa! Cannot wait to stay there again.
Reviewed on Apr 7, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Apr 19 to Apr 20
$189 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.4/10 Exceptional! (1,146 reviews)
The staff is very friendly and accommodating. The only complaint was the downstairs bar. We attended after an event; the bar was full but there was plenty of seating in the area. Unfortunately, we never got waited on nor did several other guests that were sitting nearby. Besides the bar area everything ...
Reviewed on Apr 6, 2026
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from Apr 26 to Apr 27
$226 total
Apr 26 - Apr 27
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,011 reviews)
The room was great and clean. This was supposed to have a pool and spa but it wasn’t open or available
Reviewed on Apr 7, 2026
DoubleTree by Hilton St. Louis Forest Park
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from Apr 19 to Apr 20
$154 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...
8.2/10 Very Good! (1,002 reviews)
Every thing was good, except the AC made a loud rattling sound when it would come on. Had to turn it off to sleep. I believe it was the mirror on the wall that rattled
Reviewed on Apr 7, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $147 total per night from Apr 15 to Apr 16
$147 total
Apr 15 - Apr 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.8/10 Excellent! (1,273 reviews)
The park was very expensive we stayed three days and paid 180 dollars said 40 a day very on happy with that
Reviewed on Apr 6, 2026
The Royal Sonesta Chase Park Plaza St. Louis
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$218 nightly
The price is $257 total per night from Apr 14 to Apr 15
$257 total
Apr 14 - Apr 15
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9/10 Wonderful! (1,010 reviews)
Beautiful hotel - three phenomenal restaurants. Perfect location. We absolutely love The Chase Park Plaza.
Reviewed on Apr 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels St. Ann
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in St. Ann 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in St. Ann will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in St. Ann, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent St. Ann hotel reviews by fellow wanderers
Hilton St. Louis Airport
5 out of 5
Posted 15 hours ago
Travelocity Verified Review
"Love this hotel! Very convenient and modern!"
A verified traveler stayed at Hilton St. Louis Airport
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