Explore 6 Luxury Hotels in St. Charles

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Best Luxury Hotels in St. Charles

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO
Fully refundable
$116 nightly
The price is $133 total per night from Nov 27 to Nov 28
$133 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
9.4/10 Exceptional! (1,007 reviews)
Everything was fabulous!

Reviewed on Nov 12, 2025

Opens in a new windowCountry Inn & Suites by Radisson, St. Charles Historic District
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

2 Convention Center Plz St. Charles MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $155 total per night from Nov 30 to Dec 1
$155 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the express check-in and WiFi in public areas. Enjoy ...
8.6/10 Excellent! (1,044 reviews)
Was very nice not to have to go out for dinner as they had a restaurant on the premises. Good service and good food.

Reviewed on Nov 11, 2025

Opens in a new windowEmbassy Suites by Hilton St. Louis St. Charles
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $184 total per night from Dec 7 to Dec 8
$184 total
Dec 7 - Dec 8
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,011 reviews)
Housekeeping was awesome and went above and beyond My only complaint is the hot tub closes at 6 pm

Reviewed on Nov 16, 2025

Opens in a new windowAmeristar Casino Resort and Spa
Baymont by Wyndham St. Charles

Baymont by Wyndham St. Charles

801 Veterans Memorial Parkway St. Charles MO
A gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. ...
7.8/10 Good! (1,001 reviews)
The Front Desk staff was excellent!

Reviewed on Oct 30, 2025

Opens in a new windowBaymont by Wyndham St. Charles
Relax Inn Saint Charles

Relax Inn Saint Charles

3800 Harry S Truman Blvd St. Charles MO
Fully refundable
$61 nightly
The price is $71 total per night from Nov 23 to Nov 24
$71 total
Nov 23 - Nov 24
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
6.4/10 (1,002 reviews)
Yes perfect

Reviewed on Nov 8, 2025

Opens in a new windowRelax Inn Saint Charles
Red Roof Inn St Louis - St Charles

Red Roof Inn St Louis - St Charles

2010 Zumbehl Road St. Charles MO
Free self parking is available and the hotel's front desk is staffed around-the-clock. Business travelers can take advantage of the business center. A safe deposit ...
Hotel was overbooked, was not incormed of this, paid for 3 rooms days ahead of time only to be told nothing was available upon arrival. Called a few hours before check in to confirm everything and was told everything was ready for my check in.

Reviewed on Mar 29, 2021

Opens in a new windowRed Roof Inn St Louis - St Charles
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5 star hotels in St. Charles

St. Charles Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Charles luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Charles to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Charles will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Charles, and plan your next opulent escape.


St. Charles hotels essential information

Accommodation
2,263 hotels
Lowest Price
$71
Highest Price
$583
Popular hotels
Ameristar Casino Resort and Spa, Country Inn & Suites by Radisson, St. Charles Historic District, Red Roof Inn St Louis - St Charles, Relax Inn Saint Charles , Baymont by Wyndham St. Charles, Embassy Suites by Hilton St. Louis St. Charles

Popular Luxury Stays in St. Charles

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