Explore 105 Luxury Hotels in St. Louis

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO
$425 nightly
The price is $497 total per night from Nov 20 to Nov 21
$497 total
Nov 20 - Nov 21
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,003 reviews)
Relaxing trip in a beautiful space

Reviewed on Nov 1, 2025

Opens in a new windowFour Seasons Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO
$144 nightly
The price is $168 total per night from Nov 13 to Nov 14
$168 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.4/10 Exceptional! (3,213 reviews)
Awesome

Reviewed on Nov 5, 2025

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO
$519 nightly
The price is $606 total per night from Dec 7 to Dec 8
$606 total
Dec 7 - Dec 8
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (551 reviews)
Service is exceptional!!!

Reviewed on Sep 2, 2025

Opens in a new windowThe Ritz-Carlton, St. Louis
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway, St. Louis, MO
$192 nightly
The price is $226 total per night from Nov 23 to Nov 24
$226 total
Nov 23 - Nov 24
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (1,006 reviews)
Very friendly staff. The bar and restaurant are very nice. Enjoyable stay.

Reviewed on Nov 1, 2025

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue, St. Louis, MO
$104 nightly
The price is $122 total per night from Nov 30 to Dec 1
$122 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (2,980 reviews)
Clean room. Quiet & restful. The bed is very firm. I appreciate the accessible outlets everywhere and the furniture in the room is actually useful. The free breakfast is more than most hotels and the staff is gracious. They really can't help the bizarre layout of the building & maze of hallways , ...

Reviewed on Nov 1, 2025

Opens in a new windowClayton Plaza Hotel & Extended Stay
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO
$88 nightly
The price is $104 total per night from Nov 12 to Nov 13
$104 total
Nov 12 - Nov 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,096 reviews)
Really nice hotel!

Reviewed on Nov 5, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $214 total per night from Nov 20 to Nov 21
$214 total
Nov 20 - Nov 21
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,003 reviews)
Staff was very friendly. Stay was ok, for the price.

Reviewed on Nov 6, 2025

Opens in a new windowAmeristar Casino Resort and Spa
The Westin St. Louis

The Westin St. Louis

811 Spruce St, St. Louis, MO
$118 nightly
The price is $138 total per night from Nov 23 to Nov 24
$138 total
Nov 23 - Nov 24
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.4/10 Very Good! (1,008 reviews)
Very cozy beds and nice showers

Reviewed on Oct 31, 2025

Opens in a new windowThe Westin St. Louis
Don't see what you're looking for?
See all available properties in St. Louis
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in St. Louis

5 star hotels in St. Louis

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.


St. Louis hotels essential information

Accommodation
1,681 hotels
Lowest Price
$104
Highest Price
$606
Popular hotels
The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Popular Luxury Stays in St. Louis

Recent St. Louis Hotel Reviews By Fellow Wanderers

Explore More Ways to Travel with Travelocity