Explore 105 Luxury Hotels in St. Louis

Name: Ameristar Casino Resort and Spa
Price range: $226 total
Rating: 8.4

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Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$325 nightly

$380 total

Mar 31 - Apr 1

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,000 reviews)

Great hotel!

Reviewed on Mar 16, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

Fully refundableReserve now, pay when you stay

$162 nightly

$189 total

Apr 5 - Apr 6

Total with taxes and fees

2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...

9.4/10 Exceptional! (3,354 reviews)

The breakfast food was not very good. The breakfast area was kind of dirty. There were probably a couple of hundred people going through there touching the tongs, but there was not a single hand sanitizer to be found. And this was at the height of flu season. Pretty gross.

Reviewed on Mar 28, 2026

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

$499 nightly

$583 total

Apr 5 - Apr 6

Total with taxes and fees

This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (562 reviews)

Excellent and the room service food was AMAZING. We are making this hotel our go to everytime we visit st. Louis

Reviewed on Mar 28, 2026

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

Fully refundableReserve now, pay when you stay

$184 nightly

$217 total

Apr 5 - Apr 6

Total with taxes and fees

This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

9/10 Wonderful! (1,007 reviews)

Clean and beautiful room

Reviewed on Mar 28, 2026

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

$95 nightly

$111 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

8.8/10 Excellent! (3,124 reviews)

Above average breakfast. Eggs and waffles made to order was nice. Modern and very clean. No complants at all

Reviewed on Mar 28, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

Fully refundableReserve now, pay when you stay

$124 nightly

$147 total

Apr 5 - Apr 6

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.8/10 Excellent! (1,265 reviews)

Discolored brown stains on comforter and orange stains on carpet. Restaurant has severely dusty chandeliers over the tables.

Reviewed on Mar 27, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

$131 nightly

$153 total

Apr 5 - Apr 6

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,005 reviews)

Perfect location for a Cardinals game!

Reviewed on Mar 28, 2026

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

$193 nightly

$226 total

Apr 5 - Apr 6

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.4/10 Very Good! (1,003 reviews)

Clean

Reviewed on Mar 26, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

$184 nightly

$217 total

Apr 5 - Apr 6

Total with taxes and fees

9/10 Wonderful! (1,007 reviews)

5 star hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$325 nightly

$380 total

Mar 31 - Apr 1

Total with taxes and fees

9.4/10 Exceptional! (1,000 reviews)

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.

St. Louis hotels essential information

Accommodation	1,885 hotels
Lowest Price	$111
Highest Price	$583
Popular hotels	The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Popular Luxury Stays in St. Louis

Recent St. Louis Hotel Reviews By Fellow Wanderers

Pear Tree Inn St. Louis Near Union Station

2 out of 5

Posted 3 hours ago

Travelocity Verified Review

"We had no TV reception and really wanted to watch the NCAA Tournament. So very disappointing. We wanted ice for our cooler and the ice maker on our floor was out of order. We had to go from floor to floor trying to find an ice maker that worked. Breakfast was not good at all and the breakfast area was a huge mess. We will never stay at this hotel again. "

A verified traveler stayed at Pear Tree Inn St. Louis Near Union Station