Explore 105 Luxury Hotels in St. Louis

Name: Ameristar Casino Resort and Spa
Price range: $214 total
Rating: 8.2

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Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$495 nightly

$579 total

Jul 27 - Jul 28

Total includes taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,004 reviews)

"Great hotel, loved the room"

Reviewed on Jul 19, 2025

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$140 nightly

$164 total

Jul 31 - Aug 1

Total includes taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.4/10 Exceptional! (2,871 reviews)

"Very close to everything and the excellent happy hour. What was bad was the elevators--very slow and only two out of three worked."

Reviewed on Jul 21, 2025

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO

Fully refundableReserve now, pay when you stay

$579 nightly

$674 total

Jul 27 - Jul 28

Total includes taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (539 reviews)

"Excellent"

Reviewed on Jul 18, 2025

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway, St. Louis, MO

Fully refundableReserve now, pay when you stay

$211 nightly

$249 total

Aug 24 - Aug 25

Total includes taxes and fees

This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

8.8/10 Excellent! (1,013 reviews)

"The swimming pool with full service is a wonder asset that we love to enjoy in the summer. The Chase is our favorite hotel offering world-class hospitality and amenities"

Reviewed on Jul 21, 2025

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue, St. Louis, MO

Fully refundableReserve now, pay when you stay

$99 nightly

$115 total

Aug 17 - Aug 18

Total includes taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

8.8/10 Excellent! (2,942 reviews)

"This is my favorite hotel ever since I discovered it years ago I must always stay with them. The staff are nice. The rooms are extremely clean and I love their breakfast buffet. They have a parking on the back, which is easy to get to your room from and love that there’s a lot of restaurants ..."

Reviewed on Jul 23, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO

Fully refundableReserve now, pay when you stay

$103 nightly

$122 total

Aug 3 - Aug 4

Total includes taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,015 reviews)

"The staff was very helpful. The building has a lot of charm. I would stay there again."

Reviewed on Jul 22, 2025

The Westin St. Louis

811 Spruce St, St. Louis, MO

Fully refundableReserve now, pay when you stay

$127 nightly

$148 total

Aug 3 - Aug 4

Total includes taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.4/10 Very Good! (1,011 reviews)

Would recommend

"Check-in was wonderful! The room was spacious and comfortable. The bathroom maybe a little upgrade.. but still comfy! Orlando, the valet was just amazing!!!!! Give that man a raise! The bar staff, well just one man, was kind but not very energetic- (trying to be kind). But- stillWould ..."

Reviewed on Jul 20, 2025

Ameristar Casino Resort and Spa

1 Ameristar Blvd, St. Charles, MO

Fully refundableReserve now, pay when you stay

$183 nightly

$214 total

Aug 10 - Aug 11

Total includes taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.2/10 Very Good! (1,014 reviews)

"NICE AREA TO STAY"

Reviewed on Jul 20, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in St. Louis

Live by Loews - St.Louis

799 Clark ave, St. Louis, MO

$149 nightly

$177 total

Aug 3 - Aug 4

Total includes taxes and fees

9.2/10 Wonderful! (1,015 reviews)

5 star hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

$495 nightly

$579 total

Jul 27 - Jul 28

Total includes taxes and fees

9.4/10 Exceptional! (1,004 reviews)

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.

St. Louis hotels essential information

Accommodation	1,773 hotels
Lowest Price	$115
Highest Price	$674
Popular hotels	The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel