Explore 105 Luxury Hotels in St. Louis

Name: Ameristar Casino Resort and Spa
Price range: $215 total
Rating: 8.4

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Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

Fully refundableReserve now, pay when you stay

$415 nightly

$485 total

Mar 1 - Mar 2

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,000 reviews)

Beautiful accommodations. Attentive and genuine staff. We felt like celebrities. Beyond first class service!!

Reviewed on Feb 23, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

Fully refundableReserve now, pay when you stay

$135 nightly

$158 total

Mar 3 - Mar 4

Total with taxes and fees

2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...

9.4/10 Exceptional! (3,330 reviews)

Everything was great

Reviewed on Feb 27, 2026

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

Fully refundableReserve now, pay when you stay

$499 nightly

$583 total

Mar 1 - Mar 2

Total with taxes and fees

This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (557 reviews)

Excellent hotel with various restaurants and expansive lobby area.. staff very attentive.

Reviewed on Feb 6, 2026

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO

Fully refundableReserve now, pay when you stay

$174 nightly

$205 total

Mar 1 - Mar 2

Total with taxes and fees

This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

9/10 Wonderful! (1,000 reviews)

Although the building appears older, it is very well maintained and overall extremely clean. The interior design of the hotel is also impressive. Our room was condominium-style with a separate bedroom, which made the stay very comfortable. It included a small kitchen with basic cooking equipment ...

Reviewed on Feb 23, 2026

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

$105 nightly

$122 total

Mar 29 - Mar 30

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

8.8/10 Excellent! (3,088 reviews)

Staff Checking in was quick and easy.

Reviewed on Feb 27, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

Fully refundableReserve now, pay when you stay

$106 nightly

$126 total

Mar 4 - Mar 5

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.8/10 Excellent! (1,249 reviews)

Room was filthy! Do they have maids? Bathroom was never cleaned, return sir was filthy!! Tub finish is coming off and mildew on shower walls with hair in tub and floor! Would have love a decaf coffee in room in the evening. Need updating in rooms. Room was a suite but smaller than any normal I’ve ...

Reviewed on Feb 26, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

Fully refundableReserve now, pay when you stay

$127 nightly

$148 total

Mar 8 - Mar 9

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,001 reviews)

Shower did not work. The staff moved me to another room but that room was smaller than the previous. I would’ve figured the room would’ve been equal or an upgrade since we had to relocate.

Reviewed on Feb 26, 2026

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

$184 nightly

$215 total

Mar 9 - Mar 10

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.4/10 Very Good! (1,002 reviews)

It looks like the showers are getting black mold again and the pull is to stay open later, open earlier.And you need to win more on the machines , and the parking garage needs to be fixed

Reviewed on Feb 26, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in St. Louis

River City Casino & Hotel

777 River City Casino Blvd St. Louis MO

$107 nightly

$125 total

Mar 4 - Mar 5

Total with taxes and fees

9/10 Wonderful! (1,489 reviews)

5 star hotels in St. Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$415 nightly

$485 total

Mar 1 - Mar 2

Total with taxes and fees

9.4/10 Exceptional! (1,000 reviews)

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.

St. Louis hotels essential information

Accommodation	1,868 hotels
Lowest Price	$122
Highest Price	$583
Popular hotels	The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel