Explore 105 Luxury Hotels in St. Louis

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Best Luxury Hotels in St. Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
Fully refundableReserve now, pay when you stay
$415 nightly
The price is $485 total per night from Jan 1 to Jan 2
$485 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,001 reviews)
Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home.

Reviewed on Dec 13, 2025

Opens in a new windowFour Seasons Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Dec 28 to Dec 29
$158 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.4/10 Exceptional! (3,281 reviews)
All is perfect except room cleanse

Reviewed on Dec 18, 2025

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
Fully refundableReserve now, pay when you stay
$499 nightly
The price is $583 total per night from Dec 25 to Dec 26
$583 total
Dec 25 - Dec 26
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (553 reviews)
Absolutely beautiful hotel!!! Highly recommend!

Reviewed on Nov 28, 2025

Opens in a new windowThe Ritz-Carlton, St. Louis
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $208 total per night from Jan 18 to Jan 19
$208 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (1,000 reviews)
Location is within walking distance of grocery stores, restaurants, and local shops. Valet is $50/day, self park is $40/day. On-site restaurants are great, steakhouse was excellent but very expensive. Only negatives were no full length mirror in the room, only mirror was behind sink in bathroom, ...

Reviewed on Dec 14, 2025

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Dec 28 to Dec 29
$110 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (3,033 reviews)
We arrived at 11pm and Erika at the front desk was extremely helpful. We were driving Penske 16’ truck with car carrier and Erika said we could park right in front of hotel and Police Station was right across the street. EXCELLENT rooms and Supherb FREE Breakfast buffet! Highly recommend this ...

Reviewed on Dec 18, 2025

Opens in a new windowClayton Plaza Hotel & Extended Stay
The Westin St. Louis

The Westin St. Louis

811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Dec 30 to Dec 31
$148 total
Dec 30 - Dec 31
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.6/10 Excellent! (1,000 reviews)
Everything was perfect

Reviewed on Dec 16, 2025

Opens in a new windowThe Westin St. Louis
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $106 total per night from Dec 28 to Dec 29
$106 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,157 reviews)
Excellent and restful stay. Fantastic, comfortable bed. We loved the suite - and room service. Staff was friendly and helpful. Looking forward to our next stay.

Reviewed on Dec 20, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $194 total per night from Dec 25 to Dec 26
$194 total
Dec 25 - Dec 26
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,000 reviews)
The room was impeccable and the staff were super friendly. I plan to say in the future.

Reviewed on Dec 23, 2025

Opens in a new windowAmeristar Casino Resort and Spa
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More 4 star hotels in St. Louis

5 star hotels in St. Louis

St. Louis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the St. Louis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in St. Louis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in St. Louis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in St. Louis, and plan your next opulent escape.


St. Louis hotels essential information

Accommodation
1,796 hotels
Lowest Price
$106
Highest Price
$583
Popular hotels
The Royal Sonesta Chase Park Plaza St. Louis, Ameristar Casino Resort and Spa, The Ritz-Carlton, St. Louis, Four Seasons Hotel St Louis, Clayton Plaza Hotel & Extended Stay, The Westin St. Louis, Drury Plaza Hotel St. Louis at the Arch, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Popular Luxury Stays in St. Louis

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