Photo by Geraldine Soh
Book a hotel near Historic Main Street, St. Charles Historic District
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Top hotels close to Historic Main Street

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
St. Charles MO
0.1 mi from Historic Main Street
A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Hot Tub
Kitchen

Luxurious, spa-like retreat steps from Main St.
Saint Charles MO
0.11 mi from Historic Main Street
A water park and a hot tub are featured at this smoke-free vacation home. Enjoy the sauna and conveniences like a garden and laundry facilities.
Hot Tub
Kitchen

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles MO
0.11 mi from Historic Main Street
This vacation home features a water park and laundry facilities.
Kitchen
Washer

The Otter Suite at Divine Otter
Saint Charles MO
0.15 mi from Historic Main Street
Stay at this aparthotel in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Historic Main Street are located nearby.
Kitchen
Free WiFi

The Hare Suite at Divine Otter
Saint Charles MO
0.15 mi from Historic Main Street
Stay at this aparthotel in St. Charles. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Ameristar Casino St. Charles and Historic Main Street are located nearby.
Kitchen
Free WiFi

The Wild West Getaway- 204-1
Saint Charles MO
0.16 mi from Historic Main Street
This apartment features laundry facilities.
Kitchen
Washer

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
St. Charles MO
0.17 mi from Historic Main Street
This cottage features a water park and free WiFi in public areas.
Kitchen
Free WiFi

Country Inn & Suites by Radisson, St. Charles Historic District
1190 S Main St St. Charles MO
Free Cancellation
0.62 mi from Historic Main Street
$122 nightly
The price is $141 total per night
$141 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Free Cancellation
Reserve now, pay when you stay
0.89 mi from Historic Main Street
$157 nightly
The price is $184 total per night
$184 total
Dec 7 - Dec 8
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Pool
Hot Tub

Best Western Plus The Charles Hotel
1425 South 5th Street St. Charles MO
Free Cancellation
Reserve now, pay when you stay
0.9 mi from Historic Main Street
$88 nightly
The price is $102 total per night
$102 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Comfort Suites St Charles - St Louis
1400 S 5th St St. Charles MO
Free Cancellation
Reserve now, pay when you stay
0.95 mi from Historic Main Street
$89 nightly
The price is $102 total per night
$102 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like full breakfast and free self parking.
Pool
Breakfast included

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
1.84 mi from Historic Main Street
$89 nightly
The price is $104 total per night
$104 total
Dec 15 - Dec 16
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport shuttle. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Free airport shuttle
Parking included
Don't see what you're looking for?
See all available properties in Historic Main Street
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Historic Main Street hotels essential information
Accommodation | 470 hotels |
|---|---|
Lowest Price | $102 |
Highest Price | $184 |
Popular hotels | Ameristar Casino Resort and Spa, Best Western Plus The Charles Hotel, Country Inn & Suites by Radisson, St. Charles Historic District, The St. Charles Guest House, lovely historic home, fun for families and groups, Hollywood Casino & Hotel St. Louis, 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!, 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo., Comfort Suites St Charles - St Louis, The Otter Suite at Divine Otter, Luxurious, spa-like retreat steps from Main St., The Hare Suite at Divine Otter, The Wild West Getaway- 204-1 |
Recent Historic Main Street hotel reviews by fellow wanderers

Comfort Suites St Charles - St Louis
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Great!"
A verified traveler stayed at Comfort Suites St Charles - St Louis
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