A brick-paved street lined with historic buildings and a yellow fire hydrant.

Book a hotel near Historic Main Street, St. Charles Historic District

Name: Ameristar Casino Resort and Spa
Price range: $214 total

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Top hotels close to Historic Main Street

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

St. Charles MO

0.1 mi from Historic Main Street

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A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.

Hot Tub

Kitchen

Luxurious, spa-like retreat steps from Main St.

Saint Charles MO

0.11 mi from Historic Main Street

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A water park and a hot tub are featured at this smoke-free vacation home. Enjoy the sauna and conveniences like a garden and laundry facilities.

Hot Tub

Kitchen

The Foundry Flat | Industrial-Inspired 2-Bedroom

Saint Charles MO

0.11 mi from Historic Main Street

$307 nightly

$338 total

Sep 28 - Sep 29

Total with taxes and fees

Stay at this apartment in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.

Kitchen

Pet friendly

The Rustic Revival | Charming 2BR Retreat

Saint Charles MO

0.11 mi from Historic Main Street

$303 nightly

$334 total

Sep 28 - Sep 29

Total with taxes and fees

Kitchen

Pet friendly

Driftwood Den | Boho 2BR | Dog-Friendly

Saint Charles MO

0.11 mi from Historic Main Street

$303 nightly

$334 total

Oct 4 - Oct 5

Total with taxes and fees

Kitchen

Pet friendly

Hearth & Harvest | Historic St. Charles 2BR

Saint Charles MO

0.11 mi from Historic Main Street

$301 nightly

$331 total

Sep 27 - Sep 28

Total with taxes and fees

Kitchen

Pet friendly

Stylish 2BR Retreat - Concrete & Canopy

Saint Charles MO

0.11 mi from Historic Main Street

$297 nightly

$327 total

Sep 27 - Sep 28

Total with taxes and fees

Kitchen

Pet friendly

Elegant 2BR | St Charles Entertainment Area

Saint Charles MO

0.11 mi from Historic Main Street

$287 nightly

$316 total

Sep 27 - Sep 28

Total with taxes and fees

Kitchen

Pet friendly

Riverwood Retreat | Main Street 2BR

Saint Charles MO

0.11 mi from Historic Main Street

$287 nightly

$316 total

Sep 30 - Oct 1

Total with taxes and fees

Stay at this apartment in St. Charles. Enjoy free WiFi and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.

The St. Charles Guest House, lovely historic home, fun for families and groups

St. Charles MO

0.11 mi from Historic Main Street

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This vacation home features a water park and laundry facilities.

Kitchen

Washer

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO

Free Cancellation

0.62 mi from Historic Main Street

$138 nightly

$158 total

Oct 18 - Oct 19

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Free Cancellation

Reserve now, pay when you stay

0.89 mi from Historic Main Street

$183 nightly

$214 total

Oct 12 - Oct 13

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside bar.

Pool

Hot Tub

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Historic Main Street hotels essential information

Accommodation	516 hotels
Lowest Price	$158
Highest Price	$338
Popular hotels	Ameristar Casino Resort and Spa, Country Inn & Suites by Radisson, St. Charles Historic District, The St. Charles Guest House, lovely historic home, fun for families and groups, 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo., The Foundry Flat \| Industrial-Inspired 2-Bedroom, The Rustic Revival \| Charming 2BR Retreat, Driftwood Den \| Boho 2BR \| Dog-Friendly, Hearth & Harvest \| Historic St. Charles 2BR, Stylish 2BR Retreat - Concrete & Canopy, Elegant 2BR \| St Charles Entertainment Area, Luxurious, spa-like retreat steps from Main St., Riverwood Retreat \| Main Street 2BR

Recent Historic Main Street hotel reviews by fellow wanderers

Ameristar Casino Resort and Spa

4 out of 5

Posted 2 hours ago

Travelocity Verified Review

"Clean room, check in was great."

A verified traveler stayed at Ameristar Casino Resort and Spa

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

5 out of 5

Posted 1 month ago

Travelocity Verified Review

"The home was very inviting! All of the hosts extra touches so appreciated (coffee pods, snacks, etc). Beds were comfortable and all necessities were available. A wonderful stay! We will definitely return."

A verified traveler stayed at 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.