"The first St. Charles Borromeo Church, like this one, was constructed of vertical, hewn logs placed directly in the ground: an architectural style unique to the French in the New World during the 17th and 18th centuries. The church has been rebuilt on its original location. Jesse Francis, a local preservationist with 20 years experience restoring 18th French log buildings, directed the reconstruction. The work was done completely by with period tools in the manner of the 18th century. The church is part of an on-going historical interpretive program based on a re-creation of daily activities in this old French village."

Photo by Geraldine Soh

Book a hotel near Historic Main Street, St. Charles Historic District

Name: Best Western Plus The Charles Hotel
Price range: $101 total

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Top hotels close to Historic Main Street

HUGE 2 bedroom unit on Main Street

Saint Charles MO

0.09 mi from Historic Main Street

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This apartment features laundry facilities.

Kitchen

Washer

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

St. Charles MO

0.1 mi from Historic Main Street

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A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.

Hot Tub

Kitchen

Luxurious, spa-like retreat steps from Main St.

Saint Charles MO

0.11 mi from Historic Main Street

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A water park and a hot tub are featured at this smoke-free vacation home. Enjoy the sauna and conveniences like a garden and laundry facilities.

Hot Tub

Kitchen

The St. Charles Guest House, lovely historic home, fun for families and groups

St. Charles MO

0.11 mi from Historic Main Street

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This vacation home features a water park and laundry facilities.

Kitchen

Washer

The Otter Suite at Divine Otter

Saint Charles MO

0.15 mi from Historic Main Street

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Stay at this aparthotel in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Historic Main Street are located nearby.

Kitchen

Free WiFi

The Hare Suite at Divine Otter

Saint Charles MO

0.15 mi from Historic Main Street

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Stay at this aparthotel in St. Charles. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Ameristar Casino St. Charles and Historic Main Street are located nearby.

Kitchen

Free WiFi

The Wild West Getaway- 204-1

Saint Charles MO

0.16 mi from Historic Main Street

$284 nightly

$288 total

Dec 8 - Dec 9

Total with taxes and fees

This apartment features laundry facilities.

Kitchen

Washer

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

St. Charles MO

0.17 mi from Historic Main Street

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This cottage features a water park and free WiFi in public areas.

Kitchen

Free WiFi

Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!

St. Charles MO

0.17 mi from Historic Main Street

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This vacation home features a water park, free WiFi in public areas, and a garden. Laundry facilities are provided for your convenience.

Kitchen

Washer

Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St St. Charles MO

Free Cancellation

0.62 mi from Historic Main Street

$115 nightly

$132 total

Jan 1 - Jan 2, 2026

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Free Cancellation

Reserve now, pay when you stay

0.89 mi from Historic Main Street

$166 nightly

$194 total

Dec 14 - Dec 15

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.

Pool

Hot Tub

Best Western Plus The Charles Hotel

1425 South 5th Street St. Charles MO

Free Cancellation

Reserve now, pay when you stay

0.9 mi from Historic Main Street

$87 nightly

$101 total

Dec 8 - Dec 9

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Historic Main Street hotels essential information

Accommodation	464 hotels
Lowest Price	$101
Highest Price	$288
Popular hotels	Ameristar Casino Resort and Spa, Country Inn & Suites by Radisson, St. Charles Historic District, The St. Charles Guest House, lovely historic home, fun for families and groups, 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!, 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo., Luxurious, spa-like retreat steps from Main St., The Otter Suite at Divine Otter, Best Western Plus The Charles Hotel, The Hare Suite at Divine Otter, The Wild West Getaway- 204-1, Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!, HUGE 2 bedroom unit on Main Street

Recent Historic Main Street hotel reviews by fellow wanderers

Country Inn & Suites by Radisson, St. Charles Historic District

5 out of 5

Posted 4 days ago

Travelocity Verified Review

"Our family had a great stay. The accommodations were clean, welcoming & just what we needed. We were particularly impressed with Marsha who was at the front desk throughout our holiday stay making sure we had everything we needed. She is a wonderful brand ambassador for the Radisson organization."

A verified traveler stayed at Country Inn & Suites by Radisson, St. Charles Historic District

The St. Charles Guest House, lovely historic home, fun for families and groups

5 out of 5

Posted 3 weeks ago

Travelocity Verified Review

"The house was incredible! Clean, cozy yet spacious and a perfect location 1/2 block from the historic district. Shops, eating and walking paths all just a few steps from our doorstep!"

A verified traveler stayed at The St. Charles Guest House, lovely historic home, fun for families and groups