Book a hotel near Historic Main Street, St. Charles Historic District
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Top hotels close to Historic Main Street

HUGE 2 bedroom unit on Main Street
Saint Charles MO
0.09 mi from Historic Main Street
This apartment features laundry facilities.
Kitchen
Washer

1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
St. Charles MO
0.1 mi from Historic Main Street
A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Hot Tub
Kitchen

Luxurious, spa-like retreat steps from Main St.
Saint Charles MO
0.11 mi from Historic Main Street
A water park and a hot tub are featured at this smoke-free vacation home. Enjoy the sauna and conveniences like a garden and laundry facilities.
Hot Tub
Kitchen

The Retro Retreat 3rd Floor Main Street Apartment
Saint Charles MO
0.11 mi from Historic Main Street
$289 nightly
The price is $318 total per night
$318 total
May 5 - May 6
Total with taxes and fees
Stay at this apartment in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Pet friendly

The Riverwood Retreat 3rd Floor Main Street Apt
Saint Charles MO
0.11 mi from Historic Main Street
$270 nightly
The price is $298 total per night
$298 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this apartment in St. Charles. Enjoy free WiFi and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Pet friendly

The Brick & Beam 3rd Floor Apartment
Saint Charles MO
0.11 mi from Historic Main Street
$289 nightly
The price is $318 total per night
$318 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this apartment in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Pet friendly

Hearth & Harvest | Cozy Farmhouse-Inspired 2BDR
Saint Charles MO
0.11 mi from Historic Main Street
$289 nightly
The price is $318 total per night
$318 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this apartment in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Pet friendly

The Bourbon & Brass | Speakeasy-Inspired 2BDR
Saint Charles MO
0.11 mi from Historic Main Street
$289 nightly
The price is $318 total per night
$318 total
Apr 27 - Apr 28
Total with taxes and fees
Stay at this apartment in St. Charles. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Kitchen
Pet friendly

The St. Charles Guest House, lovely historic home, fun for families and groups
St. Charles MO
0.11 mi from Historic Main Street
This vacation home features a water park and laundry facilities.
Kitchen
Washer

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
St. Charles MO
0.17 mi from Historic Main Street
This cottage features a water park and free WiFi in public areas.
Kitchen
Free WiFi

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Free Cancellation
Reserve now, pay when you stay
0.89 mi from Historic Main Street
$193 nightly
The price is $226 total per night
$226 total
Apr 27 - Apr 28
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside bar.
Pool
Hot Tub

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
1.84 mi from Historic Main Street
$122 nightly
The price is $143 total per night
$143 total
Apr 27 - Apr 28
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, and free airport shuttle. Relax with a drink at one of the 3 bars/lounges and enjoy perks like free self parking.
Free airport shuttle
Parking included
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See all available properties in Historic Main Street
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Historic Main Street hotels essential information
Accommodation | 507 hotels |
|---|---|
Lowest Price | $143 |
Highest Price | $318 |
Popular hotels | Hollywood Casino & Hotel St. Louis, Ameristar Casino Resort and Spa, 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!, 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo., The Retro Retreat 3rd Floor Main Street Apartment, HUGE 2 bedroom unit on Main Street, The Riverwood Retreat 3rd Floor Main Street Apt, The Brick & Beam 3rd Floor Apartment, Hearth & Harvest | Cozy Farmhouse-Inspired 2BDR, Luxurious, spa-like retreat steps from Main St., The Bourbon & Brass | Speakeasy-Inspired 2BDR, The St. Charles Guest House, lovely historic home, fun for families and groups |
Recent Historic Main Street hotel reviews by fellow wanderers

Hollywood Casino & Hotel St. Louis
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"A little on the higher side for the area and amenities but it is a resort. The place was clean and the staff was very welcoming. Would stay again."
A verified traveler stayed at Hollywood Casino & Hotel St. Louis
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