Explore top 2025 4 Star Hotels in James Island

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Top James Island 4 Star hotels

The Francis Marion Hotel

The Francis Marion Hotel

4 out of 5
387 King St, Charleston, SC
Fully refundableReserve now, pay when you stay
$259 nightly
The price is $295 total per night from Sep 7 to Sep 8
$295 total
Sep 7 - Sep 8
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this historic hotel. Traveling on business? Take advantage of the business center, free WiFi ...
The Francis Marion Hotel
Emeline

Emeline

4 out of 5
181 Church St, Charleston, SC
Fully refundableReserve now, pay when you stay
$264 nightly
The price is $300 total per night from Sep 22 to Sep 23
$300 total
Sep 22 - Sep 23
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...
Emeline
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

4 out of 5
20 Patriots Point Rd, Mount Pleasant, SC
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $193 total per night from Sep 7 to Sep 8
$193 total
Sep 7 - Sep 8
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free resort. Enjoy the 24-hour gym and perks like free self parking and free WiFi. ...
Harborside at Charleston Harbor Resort and Marina
HarbourView Inn

HarbourView Inn

4 out of 5
2 Vendue Range, Charleston, SC
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $341 total per night from Sep 8 to Sep 9
$341 total
Sep 8 - Sep 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the business center, ...
HarbourView Inn
The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

4.5 out of 5
28 Patriots Point Road, Mount Pleasant, SC
Fully refundableReserve now, pay when you stay
$252 nightly
The price is $285 total per night from Sep 14 to Sep 15
$285 total
Sep 14 - Sep 15
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. There's fun for all ages with a children's club and a children's ...
The Beach Club at Charleston Harbor Resort and Marina
DoubleTree by Hilton Hotel & Suites Charleston Airport

DoubleTree by Hilton Hotel & Suites Charleston Airport

4 out of 5
7401 Northwoods Blvd, North Charleston, SC
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $99 total per night from Sep 14 to Sep 15
$99 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
DoubleTree by Hilton Hotel & Suites Charleston Airport
The Loutrel

The Loutrel

4 out of 5
61 State St, Charleston, SC
Fully refundableReserve now, pay when you stay
$387 nightly
The price is $441 total per night from Sep 14 to Sep 15
$441 total
Sep 14 - Sep 15
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Guests will appreciate free perks like English breakfast and WiFi in public areas. Valet parking, a communal ...
The Loutrel
The Palmetto Hotel

The Palmetto Hotel

4 out of 5
194 East Bay Street, Charleston, SC
Fully refundableReserve now, pay when you stay
$271 nightly
The price is $309 total per night from Sep 7 to Sep 8
$309 total
Sep 7 - Sep 8
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Valet parking, ...
The Palmetto Hotel
DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant

4 out of 5
1330 Stuart Engals Blvd, Mount Pleasant, SC
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $136 total per night from Sep 15 to Sep 16
$136 total
Sep 15 - Sep 16
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Relax ...
DoubleTree by Hilton Charleston Mount Pleasant
The Vendue

The Vendue

4 out of 5
19 Vendue Range, Charleston, SC
Fully refundableReserve now, pay when you stay
$258 nightly
The price is $294 total per night from Sep 7 to Sep 8
$294 total
Sep 7 - Sep 8
Total with taxes and fees
This boutique hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and free perks like continental breakfast and WiFi in public areas. ...
The Vendue
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4 Star Hotels James Island

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in James Island 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in James Island will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in James Island, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.