Book Hotels in James Island, SC
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Top James Island hotels

Cambria Hotel Mount Pleasant – Charleston
1472 Highway 17 North Mount Pleasant SC
Fully refundable
The price is $145 total per night from May 10 to May 11
$145 total
per night
May 10 - May 11
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference ...
This is the third time we have stayed here to start an annual vacation in the Charleston area. The hotel was great on our first stay and still is. Our room had a slick design and was very comfortable. The hotel’s location is convenient for eating and shopping in Mount Pleasant, but also allows easy ...
Reviewed on Apr 27, 2026

Emeline
181 Church St Charleston SC
The price is $358 total per night from May 26 to May 27
$358 total
per night
May 26 - May 27
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...
The room was clean, well laid out and a great amount of space. We found the hotel to be great overall, the only slight consideration is the restaurant on the first floor is quite busy, you really need to make reservations most of the time. Also be mindful that if you leave the hotel or need to go ...
Reviewed on Apr 27, 2026

The Francis Marion Hotel
387 King St Charleston SC
The price is $307 total per night from May 10 to May 11
$307 total
per night
May 10 - May 11
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...
Great stay. Beautiful hotel. Central to everything.
Reviewed on Apr 27, 2026

The Ryder Hotel
237 Meeting Street Charleston SC
Fully refundableReserve now, pay when you stay
The price is $334 total per night from May 27 to May 28
$334 total
per night
May 27 - May 28
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Enjoy the outdoor pool and perks like free WiFi. Valet parking, a coffee shop, and a communal ...
Great location
Reviewed on Apr 26, 2026

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
5757 Palm Boulevard Isle of Palms SC
Fully refundableReserve now, pay when you stay
The price is $545 total per night from May 10 to May 11
$545 total
per night
May 10 - May 11
This resort features a golf course, a full-service spa, and 8 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
Multiple pools, ocean front, and food-all in one place! Close to off site restaurants and shopping. A pure gem!
Reviewed on Apr 26, 2026

Courtyard by Marriott Charleston-North Charleston
7465 NORTHSIDE DR North Charleston SC
Fully refundableReserve now, pay when you stay
The price is $108 total per night from May 10 to May 11
$108 total
per night
May 10 - May 11
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
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Reviewed on Apr 27, 2026

Harborside at Charleston Harbor Resort and Marina
20 Patriots Point Rd Mount Pleasant SC
Fully refundableReserve now, pay when you stay
The price is $261 total per night from May 25 to May 26
$261 total
per night
May 25 - May 26
A marina, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Enjoy the 24-hour gym and perks like free self parking and free WiFi. ...
Property showing signs of age. Cracked but functional sink, caulking needs attention, etc.
Reviewed on Apr 27, 2026

Tides Folly Beach, Charleston's Oceanfront Hotel
1 Center Street Highway 171 Folly Beach SC
Fully refundableReserve now, pay when you stay
The price is $277 total per night from Apr 28 to Apr 29
$277 total
per night
Apr 28 - Apr 29
This hotel's 2 restaurants, 2 bars/lounges, and outdoor pool are some of the featured amenities. Enjoy beachfront dining and relax with beach cabanas and sun ...
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Reviewed on Apr 27, 2026

Embassy Suites by Hilton Charleston Historic District
337 Meeting St Charleston SC
Fully refundableReserve now, pay when you stay
The price is $272 total per night from May 10 to May 11
$272 total
per night
May 10 - May 11
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
It was convenient walking distance to the college. Very welcoming employees and I received a text asking if we were in need of anything, even though I had put up a do not disturb sign, however, I did need extra towels and responded and they delivered accordingly. The building is old and charming. ...
Reviewed on Apr 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in James Island with star-rating
Check James Island Hotels by Star Rating

5 Star Hotels
7 properties
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Recent James Island hotel reviews by fellow wanderers

Harborside at Charleston Harbor Resort and Marina
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Property showing signs of age. Cracked but functional sink, caulking needs attention, etc."
A verified traveler stayed at Harborside at Charleston Harbor Resort and Marina
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