Explore top 2026 4 Star Hotels in James Island

Name: The Vendue
Price range: $326 total
Rating: 9.4

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Top James Island 4 Star hotels

Emeline

181 Church St Charleston SC

Fully refundableReserve now, pay when you stay

$303 nightly

$344 total

Nov 1 - Nov 2

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...

The Francis Marion Hotel

387 King St Charleston SC

$239 nightly

$272 total

Nov 1 - Nov 2

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

5757 Palm Boulevard Isle of Palms SC

Fully refundableReserve now, pay when you stay

$220 nightly

$251 total

Nov 4 - Nov 5

Total with taxes and fees

This resort features a golf course, a full-service spa, and 8 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...

8.8/10 Excellent! (1,004 reviews)

"Overall, the experience and trip was a solid four stars. The entire grounds were maintained very well, common areas were spacious and well-maintained. The main pool area in the middle of the grounds was very spacious plenty of towels plenty of chairs and space to move around and given the time of ..."

Reviewed on Oct 7, 2026

Harborside at Charleston Harbor Resort and Marina

20 Patriots Point Rd Mount Pleasant SC

Fully refundableReserve now, pay when you stay

$150 nightly

$170 total

Oct 25 - Oct 26

Total with taxes and fees

A marina, 2 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Enjoy the 24-hour gym and perks like free self parking and free WiFi. ...

HarbourView Inn

2 Vendue Range Charleston SC

Fully refundableReserve now, pay when you stay

$379 nightly

$432 total

Nov 1 - Nov 2

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Traveling on business? Take advantage of the business center, ...

The Beach Club at Charleston Harbor Resort and Marina

28 Patriots Point Road Mount Pleasant SC

Fully refundableReserve now, pay when you stay

$200 nightly

$226 total

Oct 25 - Oct 26

Total with taxes and fees

This luxury resort features a full-service spa, 2 outdoor pools, and a restaurant. There's fun for all ages with a children's club and a children's pool, and ...

9.4/10 Exceptional! (1,152 reviews)

"Rooms were nice. For the price I thought I would’ve gotten a little bit more amenities or something. The price is just for the view."

Reviewed on Oct 7, 2026

The Palmetto Hotel

194 East Bay Street Charleston SC

$401 nightly

$457 total

Nov 1 - Nov 2

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Valet parking, ...

DoubleTree by Hilton Hotel & Suites Charleston Airport

7401 Northwoods Blvd North Charleston SC

Fully refundableReserve now, pay when you stay

$84 nightly

$96 total

Oct 18 - Oct 19

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

The Ansonborough

21 Hasell Street Charleston SC

Fully refundableReserve now, pay when you stay

$233 nightly

$266 total

Nov 3 - Nov 4

Total with taxes and fees

This hotel features a 24-hour gym and a rooftop terrace. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at the bar/lounge ...

9.4/10 Exceptional! (1,189 reviews)

"Great location & neat place. Huge rooms!"

Reviewed on Oct 6, 2026

The Vendue

19 Vendue Range Charleston SC

Fully refundableReserve now, pay when you stay

$286 nightly

$326 total

Nov 1 - Nov 2

Total with taxes and fees

This boutique hotel features 2 restaurants and 2 bars/lounges. Enjoy the a rooftop terrace and free perks like continental breakfast and WiFi in public areas. ...

9.4/10 Exceptional! (1,196 reviews)

"overall great stay"

Reviewed on Oct 6, 2026

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4 Star Hotels James Island

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in James Island 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in James Island will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in James Island, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.