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Top Southeast Jacksonville hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $157 total per night from May 29 to May 30
$157 total
May 29 - May 30
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
"The suite room we had was nice with a full kitchen, dining and living area that was separate from the sleeping area. I will definitely recommend this room to anyone needing to stay near the Mayo Clinic."

Reviewed on May 22, 2026

Opens in a new windowResidence Inn By Marriott Jacksonville - Mayo Clinic Area
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 out of 5
4745 Transformation Way Jacksonville FL
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $185 total per night from May 29 to May 30
$185 total
May 29 - May 30
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free area shuttle. Self parking, a grocery/convenience ...
"Very friendly staff. New hotel so everything works and is clean and in good condition. Comfortable rooms. Some rooms don’t have a good view like the rooftop with AC equipment. Very modern look. It’s definitely my preferred place to stay in that area."

Reviewed on May 20, 2026

Opens in a new windowHilton Jacksonville At Mayo Clinic
Holiday Inn Express Jacksonville South Bartram Prk by IHG

Holiday Inn Express Jacksonville South Bartram Prk by IHG

2.5 out of 5
13934 VILLAGE LAKE CIRCLE Jacksonville FL
Fully refundable
$96 nightly
The price is $109 total per night from Jun 7 to Jun 8
$109 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 3 ...
"Great place to stay, very clean and very close to a lot of restaurants, including 95… Lots of amenities nearby"

Reviewed on May 23, 2026

Opens in a new windowHoliday Inn Express Jacksonville South Bartram Prk by IHG
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 out of 5
4791 Windsor Commons Ct Jacksonville FL
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $117 total per night from May 31 to Jun 1
$117 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"This hotel felt old and unclean. There were bugs, shower leaked, and the ac made a dripping sound."

Reviewed on May 22, 2026

Opens in a new windowHoliday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
9300 Baymeadows Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $139 total per night from May 31 to Jun 1
$139 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the express check-in and WiFi in public areas. Enjoy ...
"The couch in our room was all ripped up. The outlets in the bedroom had to be fixed to work when we arrived. This hotel really went downhill"

Reviewed on May 23, 2026

Opens in a new windowEmbassy Suites by Hilton Jacksonville Baymeadows
Delta Hotels by Marriott™ Jacksonville Deerwood

Delta Hotels by Marriott™ Jacksonville Deerwood

4 out of 5
4700 Salisbury Rd Jacksonville FL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $110 total per night from May 31 to Jun 1
$110 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. A free ...
"I came down to Jacksonville for 1 night, to watch my son play indoor football. I arrived before 8 am to Jacksonville my family and I tried to go to get breakfast on Mother’s Day and it took us over 3 hours before we sat down to eat. We drove to the hotel and asked for an early check in. The hotel ..."

Reviewed on May 23, 2026

Opens in a new windowDelta Hotels by Marriott™ Jacksonville Deerwood
Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd

2.5 out of 5
7030 Bonneval Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Jun 1 to Jun 2
$77 total
Jun 1 - Jun 2
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Everything was great. We will stay here again!"

Reviewed on May 19, 2026

Opens in a new windowBaymont by Wyndham Jacksonville/Butler Blvd
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $90 total per night from May 25 to May 26
$90 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Everything was good"

Reviewed on May 22, 2026

Opens in a new windowWyndham Garden Jacksonville
Midtown Lodge

Midtown Lodge

2.5 out of 5
4141 Philips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $82 total per night from Jun 22 to Jun 23
$82 total
Jun 22 - Jun 23
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
"Room 163: the door does not lock. The toilet paper holder is dangling from the wall, which has small divots dug out of it. There is a bit of discoloration around the tub. The staff willingly gave us another room. Inside door latches/chains have been removed and painted over. The room interiors are ..."

Reviewed on May 20, 2026

Opens in a new windowMidtown Lodge
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Jacksonville hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southeast Jacksonville Hotel & Travel Guide\n

Inspiring accommodation alternatives are plentiful in Southeast Jacksonville. Our database shows no less than 56 accommodation options within a 6-mile (10-kilometer) radius of Southeast Jacksonville's city center.

Modern travelers will find Embassy Suites Jacksonville Baymeadows and Residence Inn by Marriott Jacksonville Baymeadows within strolling distance of Southeast Jacksonville's city center.

Southeast Jacksonville features a selection of budget hotel options that will satisfy thrifty visitors. The Country Inn & Suites By Carlson, Jacksonville I-95 South is 3 miles (5 kilometers) from the heart of Southeast Jacksonville, while the Comfort Suites Baymeadows Near Butler Blvd is 1 mile (2 kilometers) away. Two other options in the cheaper range of Southeast Jacksonville hotels include the Hampton Inn Jacksonville I-295 East/Baymeadows and the Econo Lodge.

The The Lodge and Club at Ponte Vedra Beach is situated 10 miles (16 kilometers) away from central Southeast Jacksonville. An alternative place to stay is the Ponte Vedra Inn & Club, which is positioned 10 miles (16 kilometers) away. You could also check out the amenities and rates at the One Ocean Resort & Spa or the Bluegreen Vacations Grande Villas at World Golf Village.

Once you've seen Southeast Jacksonville, save some time to visit the other cultural and scenic attractions of the Northeast Florida area. Check out Northeast Florida's history museums and lighthouses. Those wanting to explore some natural spaces should also leave time to enjoy the region's beaches and wetlands. In this region of United States of America adventurous visitors might try their hand at hiking.

Looking for more things to do? Consider spending a day or two discovering Catty Shack Ranch Wildlife Sanctuary and Pecan Park Flea and Farmers' Market, which can be found in North Jacksonville, 18 miles (29 kilometers) north of Southeast Jacksonville. The Crowne Plaza Hotel Jacksonville Airport/I-95N and Hyatt Place Jacksonville Airport are just a handful of the long and short-stay choices in North Jacksonville. 10 miles (16 kilometers) to the northwest of Southeast Jacksonville, you will find Downtown Jacksonville, which is home to the Hyatt Regency Jacksonville and Riverdale Inn. The Jesse Ball Dupont Park and The Jacksonville Fire Museum are some of the most frequented points of interest to get to know should you visit Downtown Jacksonville.

Jacksonville International Airport is a convenient airport, and is 20 miles (33 kilometers) from Southeast Jacksonville's downtown area. Conveniently located Travelocity-listed hotels are Hampton Inn Suites Jacksonville Airport and Hilton Garden Inn Jacksonville Airport.

Recent Southeast Jacksonville hotel reviews by fellow wanderers

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