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Top hotels close to Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3 out of 5
14390 Mayo Boulevard Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.23 mi from Mayo Clinic Florida
$152 nightly
The price is $173 total per night
$173 total
Aug 15 - Aug 16
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy perks like free self parking.
Pool
Parking included
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 out of 5
4745 Transformation Way Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.48 mi from Mayo Clinic Florida
$151 nightly
The price is $171 total per night
$171 total
Sep 7 - Sep 8
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free area shuttle. Self parking, a grocery/convenience store, and express check-out are also offered.
Pool
Free WiFi
Light Grey Getaway under 2 miles to mayo, 4 miles to the beach

Light Grey Getaway under 2 miles to mayo, 4 miles to the beach

Jacksonville FL
0.55 mi from Mayo Clinic Florida
Get rates
A gym is featured at this vacation home, along with a garden and laundry facilities.
Kitchen
Washer
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH Jacksonville FL
0.67 mi from Mayo Clinic Florida
$137 nightly
The price is $155 total per night
$155 total
Aug 15 - Aug 16
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Private Pool Getaway • 5min Beach • Sleeps 9

Private Pool Getaway • 5min Beach • Sleeps 9

Jacksonville FL
0.78 mi from Mayo Clinic Florida
$447 nightly
The price is $500 total per night
$500 total
Aug 12 - Aug 13
Total with taxes and fees
An outdoor pool is featured at this vacation home, along with a garden and laundry facilities.
Pool
Kitchen
4BR Heated Pool, Putting Green & Outdoor Bar | Near Mayo Clinic Jacksonville | Sleeps 10 SMV

4BR Heated Pool, Putting Green & Outdoor Bar | Near Mayo Clinic Jacksonville | Sleeps 10 SMV

Jacksonville FL
0.88 mi from Mayo Clinic Florida
Get rates
This villa features a garden, laundry facilities, and barbecue grills.
Kitchen
Washer
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 out of 5
4791 Windsor Commons Ct Jacksonville FL
Free Cancellation
1.64 mi from Mayo Clinic Florida
$110 nightly
The price is $125 total per night
$125 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

3 out of 5
13741 BEACH BLVD Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
1.92 mi from Mayo Clinic Florida
$119 nightly
The price is $135 total per night
$135 total
Sep 6 - Sep 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the laundry service and free internet in public areas. There's a gym on site, and laundry facilities and free newspapers are also offered.
Breakfast included
Pet friendly
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 out of 5
13733 Beach Blvd Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
1.95 mi from Mayo Clinic Florida
$128 nightly
The price is $145 total per night
$145 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Stylish Retreat Near Beaches & Attractions - Private, Clean, Comfortable

Stylish Retreat Near Beaches & Attractions - Private, Clean, Comfortable

Jacksonville FL
2.04 mi from Mayo Clinic Florida
Get rates
This vacation home includes a garden and laundry facilities.
Kitchen
Washer
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 out of 5
1220 Marsh Landing Pkwy Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
2.58 mi from Mayo Clinic Florida
$120 nightly
The price is $136 total per night
$136 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling for business? Take advantage of the free WiFi in public areas, express check-in, and conference space. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
3.65 mi from Mayo Clinic Florida
$169 nightly
The price is $192 total per night
$192 total
Aug 11 - Aug 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a gym on site, and a 24-hour front desk and a coffee shop are also provided.
Pool
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Clinic Florida hotels essential information

Accommodation
1,989 hotels
Lowest Price
$125
Highest Price
$500
Popular hotels
Hilton Jacksonville At Mayo Clinic, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Margaritaville Jacksonville Beach, Light Grey Getaway under 2 miles to mayo, 4 miles to the beach, Private Pool Getaway • 5min Beach • Sleeps 9, 4BR Heated Pool, Putting Green & Outdoor Bar | Near Mayo Clinic Jacksonville | Sleeps 10 SMV, Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG, Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, TownePlace Suites by Marriott Jacksonville East, Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area, Stylish Retreat Near Beaches & Attractions - Private, Clean, Comfortable

Recent Mayo Clinic Florida hotel reviews by fellow wanderers

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"This hotel is in a great location. It’s always clean. The beds are comfortable. And the amenities are excellent, the hotel restaurant and bar are the perfect ending to a day at the beach!"
A verified traveler stayed at Margaritaville Jacksonville Beach
Margaritaville Jacksonville Beach

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