Photo by Amber Palmer
Book a hotel near Mayo Clinic Florida, Jacksonville
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top hotels close to Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
14390 Mayo Boulevard Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.19 mi from Mayo Clinic Florida
$152 nightly
The price is $173 total per night
$173 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy perks like free self parking.
Pool
Parking included

Hilton Jacksonville At Mayo Clinic
4745 Transformation Way Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.49 mi from Mayo Clinic Florida
$119 nightly
The price is $135 total per night
$135 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and a free area shuttle. Free WiFi in public areas, a grocery/convenience store, and express check-out are also on offer.
Pool
Parking included

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.67 mi from Mayo Clinic Florida
$144 nightly
The price is $163 total per night
$163 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Fancy private pool home in Jax beach
Jacksonville FL
0.78 mi from Mayo Clinic Florida
$326 nightly
The price is $364 total per night
$364 total
Dec 1 - Dec 2
Total with taxes and fees
An outdoor pool is featured at this vacation home, along with laundry facilities and barbecue grills.
Pool
Kitchen

Comfy Mayo Retreat; Heated Pool, Close to Beach
Jacksonville Beach FL
0.98 mi from Mayo Clinic Florida
This vacation home features a water park, laundry facilities, and barbecue grills.
Pool
Kitchen

Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach!
Jacksonville FL
1.34 mi from Mayo Clinic Florida
$360 nightly
The price is $403 total per night
$403 total
Dec 1 - Dec 2
Total with taxes and fees
This vacation home features a water park, a garden, and laundry facilities.
Kitchen
Washer

Quiet Coastal Home w/ Patio Near Beaches
Jacksonville FL
1.39 mi from Mayo Clinic Florida
Stay at this vacation home in Jacksonville Beach. Enjoy an in-room coffeemaker and air conditioning. Popular attractions St. Johns Town Center and Windsor Parke Golf Club are located nearby.
Washer
Dryer

Fun 5 Star Hot Tub/Beaches getaway Near MAYO!
Jacksonville FL
1.55 mi from Mayo Clinic Florida
$294 nightly
The price is $330 total per night
$330 total
Dec 23 - Dec 24
Total with taxes and fees
A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Hot Tub
Kitchen

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
4791 Windsor Commons Ct Jacksonville FL
Free Cancellation
1.66 mi from Mayo Clinic Florida
$99 nightly
The price is $113 total per night
$113 total
Dec 5 - Dec 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
13733 Beach Blvd Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
1.92 mi from Mayo Clinic Florida
$111 nightly
The price is $126 total per night
$126 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included

TownePlace Suites by Marriott Jacksonville East
13741 BEACH BLVD Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
1.92 mi from Mayo Clinic Florida
$108 nightly
The price is $123 total per night
$123 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the laundry service and free internet in public areas. There's a gym on site, and laundry facilities and free newspapers are also offered.
Breakfast included
Pet friendly

Margaritaville Jacksonville Beach
715 1st St N Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
3.65 mi from Mayo Clinic Florida
$132 nightly
The price is $150 total per night
$150 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a gym on site, and a 24-hour front desk and a coffee shop are also provided.
Pool
Free WiFi
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mayo Clinic Florida hotels essential information
Accommodation | 1,829 hotels |
|---|---|
Lowest Price | $113 |
Highest Price | $403 |
Popular hotels | Hilton Jacksonville At Mayo Clinic, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Margaritaville Jacksonville Beach, Fancy private pool home in Jax beach, Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG, Comfy Mayo Retreat; Heated Pool, Close to Beach, Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach!, Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, Quiet Coastal Home w/ Patio Near Beaches, TownePlace Suites by Marriott Jacksonville East, Fun 5 Star Hot Tub/Beaches getaway Near MAYO! |
Recent Mayo Clinic Florida hotel reviews by fellow wanderers

TownePlace Suites by Marriott Jacksonville East
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Both staff and room was awesome! It’s my second time staying. Will be back"
A verified traveler stayed at TownePlace Suites by Marriott Jacksonville East
More ways to wander Mayo Clinic Florida
Flights to Jacksonville
The best fares to get you there
Jacksonville Hotels
Jacksonville Vacation Rentals
Great Deals on Alternative Accommodations
Jacksonville Car Rentals
Affordable cars to get you around town
Jacksonville Vacations
Save more by combining flights, hotels and cars
Things to do in Jacksonville
Explore More Ways to Travel with Travelocity
- Jacksonville Hotels
- Beach Resorts & in Ponte Vedra Beach
- Ponte Vedra Beach Hotels
- Girvin Hotels
- Hotels near Jacksonville Beach Pier
- 4 Star Hotels in Jacksonville Beach
- Apartments in Jacksonville Beach
- Condos in Jacksonville Beach
- Cottages in Jacksonville Beach
- Extended Stay Hotels in Jacksonville Beach
- Guest Houses in Jacksonville Beach
- Arcade Hotels in Jacksonville Beach
- Beach Resorts & in Jacksonville Beach
- Casino Resorts & in Jacksonville Beach
- Cheap Hotels in Jacksonville Beach
- Convention Center Hotels in Jacksonville Beach
- Kid Friendly Hotels in Jacksonville Beach
- Golf Resorts & in Jacksonville Beach
- Hilton Hotels in Jacksonville Beach
- Historic Hotels in Jacksonville Beach
- Hotels with Suites in Jacksonville Beach
- Hotels with Early Check-in in Jacksonville Beach
- Hotels with Pools in Jacksonville Beach
- Hotels with Balconies in Jacksonville Beach
- Hotels with Free Parking in Jacksonville Beach
- Hotels with Hot Tubs in Jacksonville Beach
- Hotels with Kitchenettes in Jacksonville Beach
- La Quinta Inn & Suites Hotels in Jacksonville Beach
- Luxury Hotels in Jacksonville Beach
- Oceanfront Hotels in Jacksonville Beach
- Pet Friendly Hotels in Jacksonville Beach
- Red Roof Inn Hotels in Jacksonville Beach
- Romantic Getaways & Hotels in Jacksonville Beach
- Waterpark Hotels and Resorts in Jacksonville Beach
- Hotel Wedding Venues Hotels in Jacksonville Beach
- Jacksonville Beach Hotels
- Motels in Jacksonville Beach
- Vacation Homes in Jacksonville Beach
- Resorts in Jacksonville Beach
- Villas in Jacksonville Beach
- Old Ponte Vedra Beach Hotels
- North Beach Hotels
- Hotels near Players by the Sea
- Hotels near Sawgrass Village
- Southeast Jacksonville Hotels
- Hotels near Jacksonville Beach Golf Club
- Hotels near Beaches Town Center
- Adults Only Resorts & in Isle of Palms
- All Inclusive Resorts & in Isle of Palms
- Beach Resorts & in Isle of Palms
- Golf Resorts & in Isle of Palms
- Hotels with Free Breakfast in Isle of Palms
- Hotels with an Indoor Pool in Isle of Palms
- Oceanfront Hotels in Isle of Palms
- Pet Friendly Hotels in Isle of Palms
- Spa Resorts & in Isle of Palms
- Neptune Beach Hotels
- Hotels near TPC Sawgrass
- Hotels near St. Johns Town Center
- Sans Pareil Hotels
- Extended Stay Hotels in Beach Cities Jacksonville
- Golf Resorts & in Beach Cities Jacksonville
- Hotels with Childcare in Beach Cities Jacksonville
- Hotels with Free Parking in Beach Cities Jacksonville
- Hotels with Kitchenettes in Beach Cities Jacksonville
- Hotels with Room Service in Beach Cities Jacksonville
- Marriott Hotels & Resorts in Beach Cities Jacksonville
- Beach Cities Jacksonville Hotels
- Hotels near Morocco Shrine Center
- Atlantic Beach Hotels
- Hotels near Cradle Creek Preserve
- Sandalwood Hotels
- Hotels near Florida State College - South Campus
- Hotels near Marsh Landing Country Club
- Hotels near University of North Florida
- Hotels near Huguenot Park
- Hotels near Gonzales Park
- Hotels near Lake Forest Shopping Center
- Hotels near Windsor Commons Shopping Center
- Hotels near Dutton Island Preserve
- Hotels with an Indoor Pool in Atlantic Shores
- Hotels near Adventure Landing
- Hotels in Jacksonville Beach
- Oceanfront Hotels in Jacksonville Beach
- Pet-friendly Hotels in Jacksonville Beach
- Hotels in Jacksonville
- Flights to Jacksonville
- Car rentals in Jacksonville Beach
- Condos in Jacksonville Beach
- Jacksonville Beach vacation rentals
- Visit Adventure Landing
- Hotels in Ponte Vedra Beach
- Hotels near Mayo Clinic Florida
- Hotels with Balconies in Jacksonville Beach
- Resorts in Jacksonville Beach





