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Top hotels close to Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3 out of 5
14390 Mayo Boulevard Jacksonville FL
0.23 mi from Mayo Clinic Florida
$197 nightly
The price is $224 total per night
$224 total
Mar 20 - Mar 21
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy perks like free self parking.
Pool
Parking included
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 out of 5
4745 Transformation Way Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
0.48 mi from Mayo Clinic Florida
$181 nightly
The price is $205 total per night
$205 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and perks like free self parking and a free area shuttle. Free WiFi in public areas, a grocery/convenience store, and express check-out are also on offer.
Pool
Parking included
New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach

New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach

Jacksonville FL
0.58 mi from Mayo Clinic Florida
$417 nightly
The price is $466 total per night
$466 total
Mar 16 - Mar 17
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
Kitchen
Washer
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH Jacksonville FL
0.67 mi from Mayo Clinic Florida
$193 nightly
The price is $219 total per night
$219 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Comfy Mayo Retreat; Heated Pool, Close to Beach

Comfy Mayo Retreat; Heated Pool, Close to Beach

Jacksonville Beach FL
0.98 mi from Mayo Clinic Florida
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This vacation home features a water park, laundry facilities, and barbecue grills.
Pool
Kitchen
Quiet Coastal Home w/ Patio Near Beaches

Quiet Coastal Home w/ Patio Near Beaches

Jacksonville FL
1.39 mi from Mayo Clinic Florida
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Stay at this vacation home in Jacksonville Beach. Enjoy an in-room coffeemaker and air conditioning. Popular attractions St. Johns Town Center and Windsor Parke Golf Club are located nearby.
Washer
Dryer
Fun 5 Star Hot Tub/Beaches getaway Near MAYO!

Fun 5 Star Hot Tub/Beaches getaway Near MAYO!

Jacksonville FL
1.55 mi from Mayo Clinic Florida
$295 nightly
The price is $331 total per night
$331 total
Mar 16 - Mar 17
Total with taxes and fees
A hot tub is featured at this vacation home, along with a garden and laundry facilities. Barbecue grills are provided for your convenience.
Hot Tub
Kitchen
Amazing Centrally Located Home in Peaceful Area

Amazing Centrally Located Home in Peaceful Area

Jacksonville FL
1.58 mi from Mayo Clinic Florida
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This vacation home features laundry facilities.
Kitchen
Washer
TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East

3 out of 5
13741 BEACH BLVD Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
1.92 mi from Mayo Clinic Florida
$123 nightly
The price is $140 total per night
$140 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the laundry service and free internet in public areas. There's a gym on site, and laundry facilities and free newspapers are also offered.
Breakfast included
Pet friendly
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 out of 5
13733 Beach Blvd Jacksonville FL
Free Cancellation
Reserve now, pay when you stay
1.95 mi from Mayo Clinic Florida
$114 nightly
The price is $129 total per night
$129 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 out of 5
1220 Marsh Landing Pkwy Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
2.58 mi from Mayo Clinic Florida
$130 nightly
The price is $148 total per night
$148 total
Mar 19 - Mar 20
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling for business? Take advantage of the free WiFi in public areas, express check-in, and conference space. Guests will appreciate freebies like buffet breakfast and free self parking.
Pool
Breakfast included
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Free Cancellation
Reserve now, pay when you stay
3.65 mi from Mayo Clinic Florida
$179 nightly
The price is $203 total per night
$203 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a gym on site, and a 24-hour front desk and a coffee shop are also provided.
Pool
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Clinic Florida hotels essential information

Accommodation
1,902 hotels
Lowest Price
$129
Highest Price
$466
Popular hotels
Hilton Jacksonville At Mayo Clinic, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Margaritaville Jacksonville Beach, New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach, Comfy Mayo Retreat; Heated Pool, Close to Beach, Quiet Coastal Home w/ Patio Near Beaches, Fun 5 Star Hot Tub/Beaches getaway Near MAYO!, Amazing Centrally Located Home in Peaceful Area, TownePlace Suites by Marriott Jacksonville East, Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Recent Mayo Clinic Florida hotel reviews by fellow wanderers

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Loved it ! So convenient walking distance to locations and view of beach was awesome "
A verified traveler stayed at Margaritaville Jacksonville Beach
Margaritaville Jacksonville Beach

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