Explore top 2025 5 Star Hotels in South San Francisco

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Top South San Francisco 5 Star hotels

Claremont Resort & Club

Claremont Resort & Club

5 out of 5
41 Tunnel Road, Berkeley, CA
Fully refundableReserve now, pay when you stay
$376 nightly
The price is $428 total per night from Oct 30 to Oct 31
$428 total
Oct 30 - Oct 31
Total with taxes and fees
This luxury hotel features 3 restaurants, 3 outdoor pools, and 8 outdoor tennis courts. Bring the family and enjoy the children's club, playground, and kid-friendly ...
8.6/10 Excellent! (1,036 reviews)
"A historical hotel, it was my first time being here, and enjoyed the status of it. They were doing renovations and construction, but were mindful of quiet hours. I appreciate that they are maintaining it to keep it as a nice resort. I would stay here again if there were more deals and value ..."

Reviewed on Oct 1, 2025

Opens in a new windowClaremont Resort & Club
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill, San Francisco, CA
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $281 total per night from Oct 31 to Nov 1
$281 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...
8.8/10 Excellent! (1,381 reviews)
"Fantastic stay made even better by the amazing customer service by Kelsey. Upon check in we were warmly welcomed, and she resolved our slightly complicated reservation with efficiency and a smile. Kelsey epitomizes the grace and elegance of the Fairmont!"

Reviewed on Sep 29, 2025

Opens in a new windowFairmont San Francisco
Taj Campton Place

Taj Campton Place

5 out of 5
340 Stockton St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$208 nightly
The price is $244 total per night from Oct 19 to Oct 20
$244 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,000 reviews)
"I’ve always wanted to try this hotel on my SF trips, and now I’ll probably never stay anywhere else. A peaceful hotel with many elegant touches and professional staff."

Reviewed on Sep 29, 2025

Opens in a new windowTaj Campton Place
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St, San Francisco, CA
$446 nightly
The price is $524 total per night from Oct 31 to Nov 1
$524 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...
9.4/10 Exceptional! (1,001 reviews)
"Very clean, great food, customer service"

Reviewed on Oct 4, 2025

Opens in a new windowFour Seasons Hotel San Francisco at Embarcadero
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$309 nightly
The price is $364 total per night from Oct 31 to Nov 1
$364 total
Oct 31 - Nov 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,002 reviews)
"Stayed at the Palace a number of times in the past.. One of the best hotels when on business travel to SF. Great spacious lobby to take meetings / work out of."

Reviewed on Oct 3, 2025

Opens in a new windowPalace Hotel, a Luxury Collection Hotel, San Francisco
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5 out of 5
757 Market St, San Francisco, CA
$415 nightly
The price is $488 total per night from Oct 30 to Oct 31
$488 total
Oct 30 - Oct 31
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...
9.2/10 Wonderful! (1,005 reviews)
"Great hotel but hard to get in and out of. Small and congested entry to parking and entrance makes it hard to find and time consuming to use. Then you have the whole lobby on the 4th floor thing so every entry/exit is a 2 elevator deal."

Reviewed on Sep 21, 2025

Opens in a new windowFour Seasons Hotel San Francisco
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

5 out of 5
600 Stockton St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$386 nightly
The price is $454 total per night from Nov 1 to Nov 2
$454 total
Nov 1 - Nov 2
Total with taxes and fees
This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.2/10 Wonderful! (1,001 reviews)
"The staff go above and beyond the call of duty for guests of the hotel. It's perfectly located and in walking distance of Chinatown, North Beach and even the wharf. One notable stand out is how amazingly spacious the rooms with two queen beds are, which provide the perfect backdrop for a girl's or ..."

Reviewed on Sep 30, 2025

Opens in a new windowThe Ritz-Carlton, San Francisco
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
8 Mission St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$384 nightly
The price is $452 total per night from Nov 1 to Nov 2
$452 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...
9/10 Wonderful! (457 reviews)
"My favorite hotel in the city"

Reviewed on Sep 24, 2025

Opens in a new window1 Hotel San Francisco
Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

5 out of 5
2050 University Ave, East Palo Alto, Palo Alto, CA
$465 nightly
The price is $529 total per night from Oct 11 to Oct 12
$529 total
Oct 11 - Oct 12
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...
9.2/10 Wonderful! (657 reviews)
"Nice one"

Reviewed on Sep 16, 2025

Opens in a new windowFour Seasons Hotel Silicon Valley at East Palo Alto
Rosewood Sand Hill

Rosewood Sand Hill

5 out of 5
2825 Sand Hill Road, Menlo Park, CA
$1,039 nightly
The price is $1,176 total per night from Oct 24 to Oct 25
$1,176 total
Oct 24 - Oct 25
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi and a free area shuttle. ...
9.4/10 Exceptional! (269 reviews)
"I had a very enjoyable massage at the spa followed by the steam room. I swam laps in the pool and it was heated perfectly to 82 degrees. Food in the restaurant was tasty and service was impeccable. Although you can hear the noise from cars once inside my room it was completely quiet."

Reviewed on Oct 4, 2025

Opens in a new windowRosewood Sand Hill
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South San Francisco Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in South San Francisco to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. South San Francisco 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in South San Francisco before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent South San Francisco hotel reviews by fellow wanderers

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"They need to repair the shower flow. Water coming out is very weak. "
A verified traveler stayed at Travelodge by Wyndham San Francisco Airport North
Travelodge by Wyndham San Francisco Airport North

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