Explore top 2025 5 Star Hotels in San Mateo
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Top San Mateo 5 Star hotels
Fairmont San Francisco
950 Mason Street Atop Nob Hill, San Francisco, CA
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $317 total per night from Nov 10 to Nov 11
$317 total
Nov 10 - Nov 11
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...
8.8/10 Excellent! (1,403 reviews)
"Obviously, this is a historic, classic, original Fairmont hotel. Friendly staffs, and great services. I have absolutely nothing negative to say about this property. Firmaont San Francisco, enough said."
Reviewed on Oct 13, 2025
Taj Campton Place
340 Stockton St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$208 nightly
The price is $244 total per night from Oct 30 to Oct 31
$244 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9/10 Wonderful! (1,017 reviews)
"My happy place."
Reviewed on Oct 16, 2025
Palace Hotel, a Luxury Collection Hotel, San Francisco
2 New Montgomery St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$296 nightly
The price is $349 total per night from Oct 31 to Nov 1
$349 total
Oct 31 - Nov 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,006 reviews)
"Rooms are due for renovations. Tiny restrooms"
Reviewed on Oct 11, 2025
Shashi Hotel Mountain View Palo Alto
1625 N Shoreline Blvd, Mountain View, CA
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $166 total per night from Oct 24 to Oct 25
$166 total
Oct 24 - Oct 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.2/10 Wonderful! (1,088 reviews)
"very nice hotel. We stayed for a very short time due to a hospital visit but place was very comfortable"
Reviewed on Oct 18, 2025
The Ritz-Carlton, San Francisco
600 Stockton St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$386 nightly
The price is $454 total per night from Nov 1 to Nov 2
$454 total
Nov 1 - Nov 2
Total with taxes and fees
This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.2/10 Wonderful! (1,011 reviews)
"Excellent . Beautiful room"
Reviewed on Oct 16, 2025
Four Seasons Hotel San Francisco
757 Market St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$415 nightly
The price is $488 total per night from Oct 31 to Nov 1
$488 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...
9.4/10 Exceptional! (1,004 reviews)
"Restaurant has beautiful view of the city Staff all very friendly"
Reviewed on Oct 18, 2025
1 Hotel San Francisco
8 Mission St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$394 nightly
The price is $464 total per night from Oct 30 to Oct 31
$464 total
Oct 30 - Oct 31
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...
9/10 Wonderful! (463 reviews)
"This was definitely one of my best hotel stays. I love to travel and finding a place with such great service and a lovely aesthetic always makes the trip so much better. The staff is kind and helpful and the rooms are beautiful. A wonderful hotel that I will definitely return to."
Reviewed on Oct 16, 2025
Four Seasons Hotel San Francisco at Embarcadero
222 Sansome St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$446 nightly
The price is $524 total per night from Nov 14 to Nov 15
$524 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...
9.4/10 Exceptional! (1,008 reviews)
"Great"
Reviewed on Oct 16, 2025
Four Seasons Hotel Silicon Valley at East Palo Alto
2050 University Ave, East Palo Alto, Palo Alto, CA
Fully refundableReserve now, pay when you stay
$428 nightly
The price is $487 total per night from Oct 26 to Oct 27
$487 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...
9.2/10 Wonderful! (658 reviews)
"Nice one"
Reviewed on Sep 16, 2025
The St. Regis San Francisco
125 3rd St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$474 nightly
The price is $559 total per night from Oct 31 to Nov 1
$559 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
9.2/10 Wonderful! (684 reviews)
"We convened for breakfast and after 20 minutes, they brought a high chair. We ordered bread toast, which was served along with the bill at the conclusion of our meal. As we were loading our car with luggage, no assistance was offered, despite the clear observation that we were accompanied by young ..."
Reviewed on Sep 21, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
San Mateo Resorts & 5 Star Hotels
Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent San Mateo hotel reviews by fellow wanderers
Hyatt Regency San Francisco
5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"Been to SF more than 10 times - usually stay around union square for Moscone - but honestly this is now my fav hotel, amazing design, very unique architecture. Rooms well maintained, clean and appointed and super friendly and helpful staff, nothing was a problem and everything I asked for sorted quickly and hassle free. This isnt always the case in SF. Bonus this part of town is without all the hassles and troubles you find further up in Union square and surrounds - the walk to Moscone wasnt bad and the hotel made it worth it. Definitely will be back here if I can. "
A verified traveler stayed at Hyatt Regency San Francisco
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