Explore top 2026 4 Star Hotels in Lafayette Square

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Top Lafayette Square 4 Star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
$113 nightly
The price is $133 total per night from Nov 27 to Nov 28
$133 total
Nov 27 - Nov 28
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowHyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $173 total per night from Dec 7 to Dec 8
$173 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new window21C Museum Hotel St Louis
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $130 total per night from Nov 27 to Nov 28
$130 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowRenaissance St. Louis Airport Hotel
Moonrise Hotel

Moonrise Hotel

4 out of 5
6177 Delmar Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $166 total per night from Nov 16 to Nov 17
$166 total
Nov 16 - Nov 17
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Opens in a new windowMoonrise Hotel
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $165 total per night from Nov 15 to Nov 16
$165 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Opens in a new windowLive by Loews - St.Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from Nov 16 to Nov 17
$226 total
Nov 16 - Nov 17
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
8.8/10 Excellent! (1,088 reviews)
"We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of ..."

Reviewed on Nov 8, 2026

Opens in a new windowAmeristar Casino Resort and Spa
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $205 total per night from Nov 22 to Nov 23
$205 total
Nov 22 - Nov 23
Total with taxes and fees
This luxury hotel features 3 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9.2/10 Wonderful! (1,008 reviews)
"Enjoyed my stay at the Chase Park Plaza. Facility is great, and enormous gym in basement (as well as movie theatre off lobby) deserve a shout out. Bar makes a solid manhattan."

Reviewed on Nov 10, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $179 total per night from Nov 22 to Nov 23
$179 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowLe Méridien St. Louis Clayton
The Westin St. Louis

The Westin St. Louis

4.5 out of 5
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Nov 22 to Nov 23
$143 total
Nov 22 - Nov 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
8.8/10 Excellent! (1,004 reviews)
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Reviewed on Nov 8, 2026

Opens in a new windowThe Westin St. Louis
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $172 total per night from Nov 20 to Nov 21
$172 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-in, and free airport ...
Opens in a new windowMarriott St. Louis Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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