Explore top 2026 5 Star Hotels in San Mateo

Name: The St. Regis San Francisco
Price range: $542 total

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Top San Mateo 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill San Francisco CA

Fully refundableReserve now, pay when you stay

$351 nightly

$413 total

May 31 - Jun 1

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

9/10 Wonderful! (1,533 reviews)

"All great - fantastic experience."

Reviewed on May 22, 2026

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St San Francisco CA

Fully refundableReserve now, pay when you stay

$354 nightly

$417 total

Jun 18 - Jun 19

Total with taxes and fees

This luxury hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.2/10 Wonderful! (1,000 reviews)

"Everything was great except for checking in. The room was ready about an hour after our check-in time."

Reviewed on May 27, 2026

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St San Francisco CA

Fully refundableReserve now, pay when you stay

$461 nightly

$542 total

Jun 26 - Jun 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

9.6/10 Exceptional! (1,003 reviews)

"Fabolous stay and time. Incredible service"

Reviewed on May 11, 2026

Taj Campton Place

340 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$212 nightly

$250 total

May 31 - Jun 1

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (1,000 reviews)

"Fantastic stay in a perfect location! What a wonderful hotel in a super convenient location! We were just one block from Union Square and all of its great shops. From the moment we arrived, the staff was incredibly warm and welcoming. They were even able to accommodate an early check-in and a late ..."

Reviewed on May 26, 2026

The Ritz-Carlton, San Francisco

600 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$363 nightly

$427 total

Jun 6 - Jun 7

Total with taxes and fees

This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.4/10 Exceptional! (1,000 reviews)

"Beautiful place with an amazing service. Best in town!"

Reviewed on May 25, 2026

1 Hotel San Francisco

8 Mission St San Francisco CA

Fully refundableReserve now, pay when you stay

$415 nightly

$489 total

May 29 - May 30

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

9.2/10 Wonderful! (554 reviews)

"top-notch could notask for anything better, love the bikes! If they could add a infinity pool, that would be awesome"

Reviewed on May 25, 2026

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd Mountain View CA

Fully refundableReserve now, pay when you stay

$149 nightly

$164 total

May 30 - May 31

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.4/10 Exceptional! (1,390 reviews)

"It was great , poop area needs someone to oook over cups from people all over"

Reviewed on May 26, 2026

Four Seasons Hotel San Francisco

757 Market St San Francisco CA

Fully refundableReserve now, pay when you stay

$595 nightly

$700 total

Jun 5 - Jun 6

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

9.4/10 Exceptional! (1,003 reviews)

"We had a wonderful time, excellent food and great service."

Reviewed on May 25, 2026

The Ritz-Carlton, Half Moon Bay

1 Miramontes Point Rd Half Moon Bay CA

Fully refundableReserve now, pay when you stay

$1,073 nightly

$1,255 total

Jun 2 - Jun 3

Total with taxes and fees

This luxury hotel features a golf course, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

9.2/10 Wonderful! (676 reviews)

"Great experience as always"

Reviewed on May 26, 2026

The St. Regis San Francisco

125 3rd St San Francisco CA

Fully refundableReserve now, pay when you stay

$460 nightly

$542 total

Jun 5 - Jun 6

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

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San Mateo Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.