Explore top 2026 5 Star Hotels in San Mateo

Name: The St. Regis San Francisco
Price range: $668 total
Rating: 9.4

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Top San Mateo 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill San Francisco CA

Fully refundableReserve now, pay when you stay

$245 nightly

$288 total

Jul 5 - Jul 6

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

9/10 Wonderful! (1,550 reviews)

"Water faucet in bathroom was loose but otherwise beautiful hotel. Coffee shop was a bit disappointing."

Reviewed on Jun 24, 2026

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St San Francisco CA

Fully refundableReserve now, pay when you stay

$327 nightly

$385 total

Jul 10 - Jul 11

Total with taxes and fees

This luxury hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.2/10 Wonderful! (1,001 reviews)

"Such a great experience, will for sure stay there again"

Reviewed on Jun 28, 2026

Taj Campton Place

340 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$208 nightly

$244 total

Jul 5 - Jul 6

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (1,000 reviews)

"Always love staying here. Quiet, peaceful and a quick walk to everything fun. Love the breakfast especially the Indian options they have,"

Reviewed on Jun 19, 2026

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St San Francisco CA

Fully refundableReserve now, pay when you stay

$455 nightly

$535 total

Jul 24 - Jul 25

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd Mountain View CA

Fully refundableReserve now, pay when you stay

$199 nightly

$219 total

Jul 5 - Jul 6

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.4/10 Exceptional! (1,388 reviews)

"Love the welcome glass of champagne! Easy walking to CHM and the theater and Zareens! Beautiful and swanky hotel."

Reviewed on Jun 19, 2026

The Ritz-Carlton, San Francisco

600 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$423 nightly

$497 total

Jul 5 - Jul 6

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet ...

9.4/10 Exceptional! (1,003 reviews)

"The staff is awesome! I can’t wait to comeback!"

Reviewed on Jun 27, 2026

1 Hotel San Francisco

8 Mission St San Francisco CA

Fully refundableReserve now, pay when you stay

$372 nightly

$438 total

Jul 2 - Jul 3

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

9.2/10 Wonderful! (567 reviews)

"Solid hotel."

Reviewed on Jun 27, 2026

Treehouse Hotel Silicon Valley

N. Mathilda, 1100 Sunnyvale CA

Fully refundableReserve now, pay when you stay

$207 nightly

$233 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate complimentary bicycles, kid-friendly dining, and babysitting. Enjoy ...

9.6/10 Exceptional! (111 reviews)

"One of, if not THE nicest hotels I've stayed at while traveling for business. The restaurant was great, the gym is fantastic, the staff are wonderful, and the room was great. Great location too! Not a bad word can be said about this place."

Reviewed on Jun 26, 2026

Four Seasons Hotel San Francisco

757 Market St San Francisco CA

Fully refundableReserve now, pay when you stay

$515 nightly

$606 total

Jul 19 - Jul 20

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

9.4/10 Exceptional! (1,001 reviews)

"We stay at a lot of Four Seasons and this one seemed just like an average hotel room. It was nice but for the price you pay it should be excellent. The room was just so-so for us. We had to move rooms when we first got there because the toilet was broken. After a long day of traveling that was aggravating. ..."

Reviewed on Jun 26, 2026

The St. Regis San Francisco

125 3rd St San Francisco CA

Fully refundableReserve now, pay when you stay

$567 nightly

$668 total

Jul 12 - Jul 13

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

9.4/10 Exceptional! (729 reviews)

"I loved this hotel. Great location, staff, and ambience."

Reviewed on Jun 13, 2026

Don't see what you're looking for?

See all available properties in San Mateo

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in San Mateo

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.