Explore top 2026 5 Star Hotels in San Mateo

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Top San Mateo 5 Star hotels

Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
Fully refundableReserve now, pay when you stay
$375 nightly
The price is $441 total per night from Sep 20 to Sep 21
$441 total
Sep 20 - Sep 21
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...
Opens in a new windowFairmont San Francisco
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St San Francisco CA
Fully refundableReserve now, pay when you stay
$497 nightly
The price is $585 total per night from Oct 3 to Oct 4
$585 total
Oct 3 - Oct 4
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...
9.6/10 Exceptional! (1,002 reviews)
"Loved it! The 40th floor terrace was our favorite esp during the weekend bar hours. Great sunset and views."

Reviewed on Sep 11, 2026

Opens in a new windowFour Seasons Hotel San Francisco at Embarcadero
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St San Francisco CA
Fully refundableReserve now, pay when you stay
$372 nightly
The price is $438 total per night from Sep 19 to Sep 20
$438 total
Sep 19 - Sep 20
Total with taxes and fees
This luxury hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new windowPalace Hotel, a Luxury Collection Hotel, San Francisco
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

5 out of 5
600 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
$454 nightly
The price is $534 total per night from Sep 19 to Sep 20
$534 total
Sep 19 - Sep 20
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet ...
Opens in a new windowThe Ritz-Carlton, San Francisco
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
8 Mission St San Francisco CA
$497 nightly
The price is $585 total per night from Oct 3 to Oct 4
$585 total
Oct 3 - Oct 4
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...
9.2/10 Wonderful! (614 reviews)
"The hotel is run without any concern for service quality and cleanliness - possibly due to its unexpectedly high guest turnover. Anyhow property location is very good."

Reviewed on Sep 12, 2026

Opens in a new window1 Hotel San Francisco
Taj Campton Place

Taj Campton Place

5 out of 5
340 Stockton St San Francisco CA
$269 nightly
The price is $316 total per night from Sep 18 to Sep 19
$316 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowTaj Campton Place
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

5 out of 5
1625 N Shoreline Blvd Mountain View CA
$224 nightly
The price is $247 total per night from Sep 25 to Sep 26
$247 total
Sep 25 - Sep 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.4/10 Exceptional! (1,434 reviews)
"Shashi Hotel is really nice and well kept! Staff very helpful! There is a huge parking lot that used to be free to park. They are now charging $20 for parking. Patrons now are parking on sidewalk, which is unfortunate that such a quality hotel is having customers park on the sidewalk leaving the ..."

Reviewed on Sep 13, 2026

Opens in a new windowShashi Hotel Mountain View Palo Alto
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5 out of 5
757 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$525 nightly
The price is $618 total per night from Sep 18 to Sep 19
$618 total
Sep 18 - Sep 19
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...
Opens in a new windowFour Seasons Hotel San Francisco
Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

5 out of 5
2050 University Ave, East Palo Alto Palo Alto CA
Fully refundableReserve now, pay when you stay
$340 nightly
The price is $387 total per night from Oct 9 to Oct 10
$387 total
Oct 9 - Oct 10
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...
Opens in a new windowFour Seasons Hotel Silicon Valley at East Palo Alto
The St. Regis San Francisco

The St. Regis San Francisco

5 out of 5
125 3rd St San Francisco CA
Fully refundableReserve now, pay when you stay
$524 nightly
The price is $618 total per night from Sep 19 to Sep 20
$618 total
Sep 19 - Sep 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowThe St. Regis San Francisco
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San Mateo Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent San Mateo hotel reviews by fellow wanderers

Club Quarters Hotel Embarcadero, San Francisco

Club Quarters Hotel Embarcadero, San Francisco

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"very easy check-in. The rooms were very clean, and the beds were comfortable as well."
A verified traveler stayed at Club Quarters Hotel Embarcadero, San Francisco
Club Quarters Hotel Embarcadero, San Francisco

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