Explore top 2025 5 Star Hotels in San Mateo

Name: The St. Regis San Francisco
Price range: $559 total
Rating: 9.2

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Top San Mateo 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco, CA

Fully refundableReserve now, pay when you stay

$260 nightly

$306 total

Nov 23 - Nov 24

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

9/10 Wonderful! (1,386 reviews)

I haven’t been to the Fairmont for a few years, and was a little sad to see that it was fairly empty. The room rate was excellent, but no free coffee or gym were a bummer. I hope they change theee elements.

Reviewed on Oct 21, 2025

Taj Campton Place

340 Stockton St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$190 nightly

$223 total

Nov 26 - Nov 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,006 reviews)

A wonderful stay!

Front desk and sales staff so accommodating and thoughtful. Housekeeping is excellent. Just a warm and comfortable place to stay in the City.

Reviewed on Oct 24, 2025

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$278 nightly

$327 total

Nov 21 - Nov 22

Total with taxes and fees

This smoke-free hotel includes 2 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,002 reviews)

Beautiful hotel, well maintained, did not partake of breakfast

Reviewed on Oct 24, 2025

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd, Mountain View, CA

Fully refundableReserve now, pay when you stay

$152 nightly

$168 total

Nov 1 - Nov 2

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.2/10 Wonderful! (1,104 reviews)

Large boutique hotel with great amenities for a short business trip

Reviewed on Oct 22, 2025

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$341 nightly

$401 total

Nov 23 - Nov 24

Total with taxes and fees

This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.2/10 Wonderful! (999 reviews)

In particular, I absolutely loved the Bellmen!! They were most helpful and just lovely!! This morning, especially, they saved us from getting into the wrong Uber!!The Uber driver was inattentive, so much so, that we would have ended up in Las Vegas, instead of the SanFran airport!! Thank you ...

Reviewed on Oct 19, 2025

Four Seasons Hotel San Francisco

757 Market St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$395 nightly

$465 total

Oct 30 - Oct 31

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

9.4/10 Exceptional! (1,006 reviews)

Everything was amazing. Friendly staff, and great location

Reviewed on Oct 20, 2025

1 Hotel San Francisco

8 Mission St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$374 nightly

$440 total

Nov 21 - Nov 22

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

9/10 Wonderful! (464 reviews)

This was definitely one of my best hotel stays. I love to travel and finding a place with such great service and a lovely aesthetic always makes the trip so much better. The staff is kind and helpful and the rooms are beautiful. A wonderful hotel that I will definitely return to.

Reviewed on Oct 16, 2025

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$421 nightly

$495 total

Nov 22 - Nov 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

9.4/10 Exceptional! (1,011 reviews)

Rooms great location, friendly and hospitable staff. Great experience overall!

Reviewed on Oct 18, 2025

Four Seasons Hotel Silicon Valley at East Palo Alto

2050 University Ave, East Palo Alto, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$450 nightly

$512 total

Nov 15 - Nov 16

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...

9.2/10 Wonderful! (659 reviews)

Nice one

Reviewed on Sep 16, 2025

The St. Regis San Francisco

125 3rd St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$474 nightly

$559 total

Nov 14 - Nov 15

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

9.2/10 Wonderful! (684 reviews)

We convened for breakfast and after 20 minutes, they brought a high chair. We ordered bread toast, which was served along with the bill at the conclusion of our meal. As we were loading our car with luggage, no assistance was offered, despite the clear observation that we were accompanied by young ...

Reviewed on Sep 21, 2025

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San Mateo Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent San Mateo hotel reviews by fellow wanderers

Crowne Plaza San Francisco Airport by IHG

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"Great room, clean, newly updated, and allowed to enter room early for check on. Easy walk across footbridge to Burlingame Village with lots of dining options. The best value and hotel in Burlingame."

A verified traveler stayed at Crowne Plaza San Francisco Airport by IHG