Explore top 2026 5 Star Hotels in San Mateo

Name: The St. Regis San Francisco
Price range: $523 total
Rating: 9.4

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Top San Mateo 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill San Francisco CA

Fully refundableReserve now, pay when you stay

$285 nightly

$335 total

May 25 - May 26

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

9/10 Wonderful! (1,534 reviews)

"Air conditioning wasn’t working great"

Reviewed on May 17, 2026

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St San Francisco CA

Fully refundableReserve now, pay when you stay

$327 nightly

$385 total

May 28 - May 29

Total with taxes and fees

This luxury hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.2/10 Wonderful! (1,005 reviews)

"The building itself is truly impressive, with a sense of history and grandeur that makes a strong first impression. The location is also excellent, very convenient for exploring San Francisco. That said, some areas of the hotel feel dated. The hallways in particular look old and have a harsh white ..."

Reviewed on May 4, 2026

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St San Francisco CA

Fully refundableReserve now, pay when you stay

$446 nightly

$525 total

Jun 5 - Jun 6

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

9.6/10 Exceptional! (1,001 reviews)

"Fabolous stay and time. Incredible service"

Reviewed on May 11, 2026

Taj Campton Place

340 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$253 nightly

$297 total

May 22 - May 23

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (1,004 reviews)

"No"

Reviewed on May 13, 2026

The Ritz-Carlton, San Francisco

600 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$363 nightly

$427 total

May 25 - May 26

Total with taxes and fees

This luxury hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.4/10 Exceptional! (1,001 reviews)

"The breakfast is to expensive and no one eat because of the price! The parking if you have a car is more than 100$ US per night, this is a shame and really bad"

Reviewed on May 3, 2026

1 Hotel San Francisco

8 Mission St San Francisco CA

Fully refundable

$407 nightly

$479 total

May 25 - May 26

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

9.2/10 Wonderful! (547 reviews)

"breakfast super and didn't use sap"

Reviewed on May 16, 2026

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd Mountain View CA

Fully refundableReserve now, pay when you stay

$149 nightly

$164 total

May 21 - May 22

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.4/10 Exceptional! (1,384 reviews)

"Very nice"

Reviewed on May 18, 2026

Four Seasons Hotel San Francisco

757 Market St San Francisco CA

Fully refundableReserve now, pay when you stay

$515 nightly

$606 total

May 25 - May 26

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

9.4/10 Exceptional! (1,002 reviews)

"Clean room. Very friendly staff. Wonderful stay."

Reviewed on Apr 30, 2026

The Ritz-Carlton, Half Moon Bay

1 Miramontes Point Rd Half Moon Bay CA

Fully refundableReserve now, pay when you stay

$983 nightly

$1,150 total

May 25 - May 26

Total with taxes and fees

This luxury hotel features a golf course, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

The St. Regis San Francisco

125 3rd St San Francisco CA

Fully refundableReserve now, pay when you stay

$444 nightly

$523 total

May 29 - May 30

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

9.4/10 Exceptional! (725 reviews)

"The St Regis is the most accommodating hotel we have experienced period. We were so impressed with the hospitality and the attention to detail. The staff is committed to giving you a great experience and it's showed from the time we walked through the door. I want to give a special shout out to Daniel ..."

Reviewed on Apr 29, 2026

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San Mateo Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.