Explore top 2026 5 Star Hotels in San Mateo

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Top San Mateo 5 Star hotels

Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
Fully refundableReserve now, pay when you stay
$370 nightly
The price is $435 total per night from Sep 20 to Sep 21
$435 total
Sep 20 - Sep 21
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...
Opens in a new windowFairmont San Francisco
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

5 out of 5
222 Sansome St San Francisco CA
Fully refundableReserve now, pay when you stay
$480 nightly
The price is $565 total per night from Oct 2 to Oct 3
$565 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...
Opens in a new windowFour Seasons Hotel San Francisco at Embarcadero
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

5 out of 5
2 New Montgomery St San Francisco CA
Fully refundableReserve now, pay when you stay
$390 nightly
The price is $459 total per night from Oct 16 to Oct 17
$459 total
Oct 16 - Oct 17
Total with taxes and fees
This luxury hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new windowPalace Hotel, a Luxury Collection Hotel, San Francisco
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

5 out of 5
600 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
$482 nightly
The price is $567 total per night from Oct 16 to Oct 17
$567 total
Oct 16 - Oct 17
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet ...
9.4/10 Exceptional! (1,000 reviews)
"Very Good location, very nice smell in the lobby and and the Beautiful San Francisco with the best restaurants around!!!"

Reviewed on Sep 14, 2026

Opens in a new windowThe Ritz-Carlton, San Francisco
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
8 Mission St San Francisco CA
Fully refundableReserve now, pay when you stay
$497 nightly
The price is $585 total per night from Oct 3 to Oct 4
$585 total
Oct 3 - Oct 4
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...
Opens in a new window1 Hotel San Francisco
Taj Campton Place

Taj Campton Place

5 out of 5
340 Stockton St San Francisco CA
$232 nightly
The price is $273 total per night from Sep 17 to Sep 18
$273 total
Sep 17 - Sep 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.2/10 Wonderful! (1,000 reviews)
"We had a few hiccups when we arrived. The doorman brought our bags to the room but didn't mention the amenities. He was very nonchalant about it, and when we asked about the air conditioning, he just pointed to the unit. Nowadays, the customer service level seems laissez-faire because of staff turnover ..."

Reviewed on Sep 14, 2026

Opens in a new windowTaj Campton Place
Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto

5 out of 5
1625 N Shoreline Blvd Mountain View CA
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $219 total per night from Sep 18 to Sep 19
$219 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowShashi Hotel Mountain View Palo Alto
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

5 out of 5
757 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$510 nightly
The price is $600 total per night from Sep 20 to Sep 21
$600 total
Sep 20 - Sep 21
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...
Opens in a new windowFour Seasons Hotel San Francisco
Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

5 out of 5
2050 University Ave, East Palo Alto Palo Alto CA
Fully refundableReserve now, pay when you stay
$340 nightly
The price is $387 total per night from Oct 9 to Oct 10
$387 total
Oct 9 - Oct 10
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...
9.4/10 Exceptional! (708 reviews)
"It’s fine but didn’t feel like the four seasons I know. The pool service was below average. The bartender at Quattro on Monday night was disappointing. The guy on Sunday night was great. On Monday we ordered a single fortaleza ranch water, when is saw the charge of $55 for the one drink I questioned ..."

Reviewed on Sep 13, 2026

Opens in a new windowFour Seasons Hotel Silicon Valley at East Palo Alto
The St. Regis San Francisco

The St. Regis San Francisco

5 out of 5
125 3rd St San Francisco CA
Fully refundableReserve now, pay when you stay
$527 nightly
The price is $621 total per night from Oct 2 to Oct 3
$621 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowThe St. Regis San Francisco
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San Mateo Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent San Mateo hotel reviews by fellow wanderers

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

4 out of 5
Posted less than an hour ago
Travelocity Verified Review
"The hotel is in an excellent location just a few steps from Union Square, the cable car stop, and the BART train station, not to mention all the clothing stores and food options around it. The room was clean and very comfortable with a refrigerator inside, and I really liked the free cookies, apples, and water in the lobby. However, the service from the lobby staff could be improved, as they misplaced my small suitcase and only found it after checking three times. Management should improve staff training so they follow protocols and do not affect customers. I would stay at the hotel again, but I would be careful with the lobby staff."
A verified traveler stayed at Chancellor Hotel on Union Square
Chancellor Hotel on Union Square

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