Explore top 2026 5 Star Hotels in San Mateo

Name: The St. Regis San Francisco
Price range: $591 total
Rating: 9.4

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Top San Mateo 5 Star hotels

Fairmont San Francisco

950 Mason Street Atop Nob Hill San Francisco CA

Fully refundableReserve now, pay when you stay

$295 nightly

$347 total

Aug 17 - Aug 18

Total with taxes and fees

A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, express ...

Taj Campton Place

340 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$226 nightly

$265 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St San Francisco CA

Fully refundableReserve now, pay when you stay

$345 nightly

$406 total

Jul 31 - Aug 1

Total with taxes and fees

This luxury hotel includes 2 restaurants, an indoor pool, and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.2/10 Wonderful! (1,000 reviews)

"although the room was clean, one of the water glasses in the bathroom was chipped and i cut my lip on it. the signage about taking stuff and having it billed to us later was unexpected and strange. i thought breakfast was included but we were charged for it. the staff was polite and professional ..."

Reviewed on Jul 15, 2026

Four Seasons Hotel San Francisco at Embarcadero

222 Sansome St San Francisco CA

Fully refundableReserve now, pay when you stay

$459 nightly

$540 total

Aug 13 - Aug 14

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. Traveling on ...

9.6/10 Exceptional! (1,000 reviews)

"Amazing view of the San Francisco Bay."

Reviewed on Jul 8, 2026

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd Mountain View CA

Fully refundableReserve now, pay when you stay

$169 nightly

$186 total

Jul 18 - Jul 19

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

The Ritz-Carlton, San Francisco

600 Stockton St San Francisco CA

Fully refundableReserve now, pay when you stay

$386 nightly

$454 total

Aug 9 - Aug 10

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet ...

Treehouse Hotel Silicon Valley

N. Mathilda, 1100 Sunnyvale CA

Fully refundableReserve now, pay when you stay

$213 nightly

$241 total

Jul 24 - Jul 25

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate complimentary bicycles, kid-friendly dining, and babysitting. Enjoy ...

1 Hotel San Francisco

8 Mission St San Francisco CA

Fully refundableReserve now, pay when you stay

$397 nightly

$467 total

Aug 2 - Aug 3

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the in-room fitness and perks like free WiFi. There's a ...

9.2/10 Wonderful! (579 reviews)

"Immediately greeted when we pulled into the private round about. They helped with our luggage. We had a speedy check in. The hotels smells amazing! My friend literally says omg! Carmen this smells like one of your perfumes! It was delightful. The rooms are beautiful and very clean. We are so happy ..."

Reviewed on Jul 11, 2026

Four Seasons Hotel San Francisco

757 Market St San Francisco CA

Fully refundableReserve now, pay when you stay

$475 nightly

$559 total

Aug 16 - Aug 17

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate kid-friendly dining and in-room childcare. Enjoy ...

9.4/10 Exceptional! (1,000 reviews)

"In general, a comfortable hotel, good room size, pleasant interactions with staff. Wonderful breakfast. Parking seemed expensive at $100/night but I have nothing to compare it to. Only thing that seemed off was the thin, uncomfortable toilet paper."

Reviewed on Jul 16, 2026

The St. Regis San Francisco

125 3rd St San Francisco CA

$501 nightly

$591 total

Jul 23 - Jul 24

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

9.4/10 Exceptional! (730 reviews)

"I loved this hotel. Great location, staff, and ambience."

Reviewed on Jun 13, 2026

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San Mateo Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in San Mateo to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. San Mateo 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in San Mateo before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.