Explore top 2025 4 Star Hotels in Clayton
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Clayton 4 Star hotels

Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $117 total per night from Nov 23 to Nov 24
$117 total
Nov 23 - Nov 24
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
8.4/10 Very Good! (3,996 reviews)
Perfect spot! Walking distance to everything downtown STL.
Reviewed on Nov 3, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $104 total per night from Nov 9 to Nov 10
$104 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.6/10 Excellent! (1,078 reviews)
The app to pay for the valet was hard to get into.
Reviewed on Oct 31, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $165 total per night from Nov 23 to Nov 24
$165 total
Nov 23 - Nov 24
Total with taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...
8.4/10 Very Good! (1,037 reviews)
Great
Reviewed on Nov 5, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive, St. Louis, MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $150 total per night from Nov 10 to Nov 11
$150 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
8.8/10 Excellent! (1,011 reviews)
very blue room, very strange decor - in a pleasant way
Reviewed on Nov 1, 2025

The Cheshire
6300 Clayton Rd, Richmond Heights, MO
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $153 total per night from Nov 23 to Nov 24
$153 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.4/10 Very Good! (1,005 reviews)
Everything was wonderful. The breakfast was awesome
Reviewed on Nov 1, 2025

21C Museum Hotel St Louis
1528 Locust street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $168 total per night from Nov 26 to Nov 27
$168 total
Nov 26 - Nov 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,435 reviews)
Loved this hotel. Nice atmosphere
Reviewed on Nov 1, 2025

DoubleTree by Hilton St. Louis Airport
4505 Woodson Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $139 total per night from Nov 10 to Nov 11
$139 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...
7.8/10 Good! (837 reviews)
Everything was great. I’m a frequent and never had issues.
Reviewed on Oct 29, 2025

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road, St. Louis, MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 21 to Nov 22
$138 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,032 reviews)
Staff was excellent
Reviewed on Oct 26, 2025

Marriott St. Louis Grand
800 Washington Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $151 total per night from Nov 22 to Nov 23
$151 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (1,016 reviews)
Stay for one day with family and property is good
Reviewed on Oct 25, 2025

Live by Loews - St.Louis
799 Clark ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Nov 20 to Nov 21
$177 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9.2/10 Wonderful! (1,066 reviews)
Breakfast was to order, great service!
Reviewed on Nov 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Clayton hotel reviews by fellow wanderers

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The breakfast was very nice, also workers and front desk people where so polite, and respectful I loved everything about it will let everyone I know will recommend and I and my husband will definitely be back real soon thank you Soo much ..... Pass 5 stars in my opinion "
A verified traveler stayed at Hampton Inn St. Louis-Downtown (At the Gateway Arch)
More ways to wander Clayton
Explore More Ways to Travel with Travelocity
- 5 Star Hotels in Concord
- Hotels near U City Big Bend Station
- 3 Star Hotels in St. Ann
- 3 Star Hotels in Sappington
- 4 Star Hotels in Sappington
- 3 Star Hotels in Chesterfield
- 4 Star Hotels in Chesterfield
- 5 Star Hotels in Chesterfield
- 5 Star Hotels in Lindenwood Park
- Hotels near The Focal Point
- 3 Star Hotels in Harvester
- 4 Star Hotels in Lafayette Square
- Hotels near Dennis and Judith Jones Visitor and Education Center
- Downtown Clayton Hotels
- Extended Stay Hotels in Richmond Heights
- Guest Houses in Richmond Heights
- Cheap Hotels in Richmond Heights
- Hotels with Hot Tubs in Richmond Heights
- Luxury Hotels in Richmond Heights
- Richmond Heights Hotels
- Vacation Homes in Richmond Heights
- Villas in Richmond Heights
- 4 Star Hotels in Frontenac
- 4 Star Hotels in Soulard
- Hotels near Washington University in St. Louis
- 3 Star Hotels in Maryland Heights
- Hotels near Saint Louis Galleria Mall
- 4 Star Hotels in Spanish Lake
- Apartments in Clayton Station
- 3 Star Hotels in St. Charles
- 4 Star Hotels in St. Charles
- 3 Star Hotels in Downtown St. Louis
- 4 Star Hotels in Downtown St. Louis
- 5 Star Hotels in Downtown St. Louis
- Apartments in Richmond Heights Station
- Motels in Richmond Heights Station
- 4 Star Hotels in University City
- Beach Resorts & in University City
- Boutique Hotels in University City
- Cheap Hotels in University City
- Hotels with Suites in University City
- Hotels with an Indoor Pool in University City
- University City Hotels
- 5 Star Hotels in Brentwood
- Apartments in Brentwood
- B&B in Brentwood
- Condos in Brentwood
- Extended Stay Hotels in Brentwood
- Convention Center Hotels in Brentwood
- Kid Friendly Hotels in Brentwood
- Hotels with Suites in Brentwood
- Hotels with Balconies in Brentwood
- Hotels with Bar in Brentwood
- Hotels with Hot Tubs in Brentwood
- Hotels with an Indoor Pool in Brentwood
- Spa Resorts & in Brentwood
- Brentwood Hotels
- Motels in Brentwood
- Villas in Brentwood
- Clayton-Tamm Hotels
- Hotels near Center of Creative Arts
- 3 Star Hotels in St. Louis
- 4 Star Hotels in St. Louis
- 5 Star Hotels in St. Louis
- St. Louis Hotels
- Condos in Skinker Station
- 4 Star Hotels in Overland
- Hotels near Mildred Lane Kemper Art Museum
- Historic Hotels in Dogtown
- Dogtown Hotels
- Condos in Forest Park Station
- Hotels near St. Louis Zoo
- 5 Star Hotels in Earth City
- Hotels near Tivoli Theatre
- Hotels near Chapel of St. Timothy And St. Titus
- Maplewood Hotels
- 3 Star Hotels in Ferguson
- 4 Star Hotels in Berkeley
- Hotels near St. Louis Art Museum
- 4 Star Hotels in Hazelwood
- 4 Star Hotels in Ellisville
- Flights to St. Louis
- Visit St. Louis Zoo
- Hotels near Washington University in St. Louis
- Hotels near St. Louis Zoo
- Visit Missouri History Museum
- Hotels in University City
- Hotels in Richmond Heights
- Hotels in St. Louis
- Hotels in Brentwood
- Visit Saint Louis Galleria Mall
- Hotels near Saint Louis Galleria Mall





