Find a Hotel in Downtown Clayton
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Top hotels in Downtown Clayton

Drury Plaza Hotel St. Louis at the Arch
First time staying at a Drury hotel. Room was spacious and clean. Breakfast was better than most. Could make a meal of happy hour food which exceeded our expectations. Staff were super friendly and helpful. Highly recommended.
Reviewed on Jan 13, 2026

The Ritz-Carlton, St. Louis
Great property. Concierge level wonderful.
Reviewed on Jan 2, 2026

AC Hotel St. Louis Clayton
The room was very clean
Reviewed on Jan 7, 2026

21C Museum Hotel St Louis
The staff was really kind
Reviewed on Jan 14, 2026

Clayton Plaza Hotel & Extended Stay
Overall great experience and amazing facility the pillows could use a upgrade but overall very happy.
Reviewed on Jan 12, 2026

Le Méridien St. Louis Clayton
Nice
Reviewed on Jan 5, 2026

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
No, the room wasn't spotless. One of the ottomans underneath the desk has some type of white crumbs or something on it. Other than that, the hospitality was nice.
Reviewed on Jan 11, 2026

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Wonderful stay
Reviewed on Jan 8, 2026

Hyatt Regency St. Louis at The Arch
Room was clean, excellent view!
Reviewed on Jan 13, 2026
Downtown Clayton Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Downtown Clayton area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown Clayton to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Downtown Clayton are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Downtown Clayton hotel reviews by fellow wanderers

Drury Plaza Hotel St. Louis at the Arch
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