Find a Hotel in Downtown Clayton
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Top hotels in Downtown Clayton

Drury Plaza Hotel St. Louis at the Arch
Provided breakfast and dinner. Also three complimentary drinks at dinner!
Reviewed on Nov 14, 2025

AC Hotel St. Louis Clayton
Clean , modern rooms
Reviewed on Nov 10, 2025

21C Museum Hotel St Louis
Great vibes
Reviewed on Nov 14, 2025

Clayton Plaza Hotel & Extended Stay
Staff was helpful to assist as this was our first time staying here and the layout can be a bit confusing if you’ve never been here. Garage parking. There was only one wash cloth in the room and the shampoo was empty. Although the stock body wash and conditioner was nice. Along with good channel ...
Reviewed on Nov 14, 2025

Le Méridien St. Louis Clayton
Small rooms but beautiful lobby.
Reviewed on Oct 27, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Parking was a mess and super expensive
Reviewed on Nov 14, 2025

Hyatt Regency St. Louis at The Arch
Nice hotel close to the arch. Ruth steakhouse is right inside hotel. Staff pleasant
Reviewed on Nov 15, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
great check in.
Reviewed on Nov 14, 2025

Forest Park Hotel by MDR
N/A. Good weather so just left the sliding door open. Needed the conference room for a family dinner. They went out of their way to make it comfortable. Very good staff! Friendly and helpful. Location is excellent for exploring “The Hill.”
Reviewed on Nov 15, 2025
Downtown Clayton Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Downtown Clayton area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown Clayton to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity ’s mission is to get you off-the-beaten path and the hotels near Downtown Clayton are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Downtown Clayton hotel reviews by fellow wanderers
Pear Tree Inn St. Louis Airport
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