Book Hotels in Los Osos, CA
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Los Osos hotels

Quality Suites Downtown San Luis Obispo
Clean room
Reviewed on Apr 7, 2026

SeaCrest OceanFront Hotel
This hotel was a fantastic place for our family to gather. Great view of the ocean, wonderful lawn area for kids to play with games available, so fun to sit at one of the many fire pits and have a cocktail and watch the sunset. Parking is free, staff is great and the rooms are very comfortable. We ...
Reviewed on Apr 12, 2026

Madonna Inn
The pool is nice but very crowded, you can also get drinks up there but they had only one, very overwhelmed, bartender working. The rooms are always lovely and quirky, but the walls must be paper thin, as we could hear EVERYTHING from the room above us. Staff was welcoming and helpful.
Reviewed on Apr 11, 2026

Oxford Suites Pismo Beach
Delicious breakfast, clean room, quiet at night.
Reviewed on Apr 11, 2026

Cottage Inn By The Sea
Love that they are dog friendly and our room has an unobstructed view of the ocean
Reviewed on Apr 10, 2026

Sandcastle Hotel on the Beach
Everything was so wonderful
Reviewed on Apr 10, 2026

Best Western Casa Grande Inn
We had a great stay here. Room was clean and comfortable. We enjoyed the hot tub and free breakfast. The staff were friendly.
Reviewed on Apr 12, 2026

Spyglass Inn
Staff was friendly and helpful. However room was not clean. Carpets were dark with stains. Walls had stains on them. Bugs were seen throughout the room. Linens had hair from previous occ
Reviewed on Apr 11, 2026

Edgewater Inn And Suites
The staff was nice but we when we checked in, they’re instructions to get to our room was to go back out in the street, turn right, go past the laundry mat and then pull in. We thought it was a little strange because the rooms looked like they were right there. I will say the room was clean but very ...
Reviewed on Apr 12, 2026
Hotels in Los Osos with star-rating
Check Los Osos Hotels by Star Rating

4 Star Hotels

3 Star Hotels
Los Osos Hotel & Travel Guide\n
If you're not sure how to begin planning your San Luis Obispo trip, rest assured, because there's no end of perfect accommodation options in Los Osos. Thanks to our handy accommodation guide, you can explore 30 rooms within 6 miles (10 kilometers) of Los Osos's downtown region.
The Sea Pines is a great option for your stay because it is one of the most ideally located options, one of only a small number of choices that are within walking distance of the Los Osos central area.
The Dolphin Bay Resort And Spa is approximately 12 miles (19 kilometers) outside of the center of Los Osos. Another alternative is the Avila La Fonda Hotel, which is situated 9 miles (15 kilometers) away. Other possible hotel options are the Avila Lighthouse Suites and the San Luis Bay Inn.
Should you have the time, you could travel to other parts of the Central California region. Photograph the scenery of Central California's valleys and rolling hills. You could also wind your way through many of the area's lighthouses. In this corner of United States of America adventurous visitors might also try their hand at snowboarding, skiing and mountain biking.
14 miles (22 kilometers) away from Los Osos, you'll reach Pismo Beach, where you can spend the day visiting Pismo Beach Pier and Monarch Butterfly Grove. If you'd like to spend a few nights in Pismo Beach, check out the Sandcastle Inn and Pismo Lighthouse Suites. 9 miles (15 kilometers) to the southeast of Los Osos, is Avila Beach, which is home to the Avila Village Inn and Inn At Avila Beach. If you visit Avila Beach, keep a day to explore the Avila Beach Golf Resort and Central Coast Aquarium.
Get yourself a serving of local sport with a journey to Alex G. Spanos Stadium, which is 9 miles (15 kilometers) to the east of Los Osos. Wise travelers that want to book Travelocity-listed accommodation nearby can choose from the Madonna Inn or the Granada Hotel & Bistro.
San Luis Obispo County Regional Airport is located 11 miles (18 kilometers) outside Los Osos's town center. Modern visitors who desire to find accommodation in the area can find a night at the Courtyard by Marriott San Luis Obispo or Embassy Suites by Hilton San Luis Obispo.
Frequently asked questions
Recent Los Osos hotel reviews by fellow wanderers

Edgewater Inn And Suites
Explore More Ways to Travel with Travelocity
- Hotels near Museum of Natural History
- Hotels near Morro Bay State Park
- Hotels near Cerro San Luis Obispo
- Hotels near Madonna Plaza Shopping Center
- Hotels near Morro Strand State Beach
- Hotels near Los Osos Oaks State Reserve
- Hotels near Cuesta College
- Hotels near Sierra Vista Regional Medical Center
- 3 Star Hotels in Morro Bay
- 4 Star Hotels in Morro Bay
- 5 Star Hotels in Morro Bay
- Farmstay in Morro Bay
- B&B in Morro Bay
- Cabins in Morro Bay
- Condos in Morro Bay
- Cottages in Morro Bay
- Extended Stay Hotels in Morro Bay
- Arcade Hotels in Morro Bay
- Beach Resorts & in Morro Bay
- Cheap Hotels in Morro Bay
- Convention Center Hotels in Morro Bay
- Kid Friendly Hotels in Morro Bay
- Golf Resorts & in Morro Bay
- Green Hotels in Morro Bay
- Hilton Hotels in Morro Bay
- Historic Hotels in Morro Bay
- Hotels with Suites in Morro Bay
- Hotels with Early Check-in in Morro Bay
- Hotels with Pools in Morro Bay
- Hotels with Air Conditioning in Morro Bay
- Hotels with Balconies in Morro Bay
- Hotels with Bar in Morro Bay
- Hotels with Hot Tubs in Morro Bay
- Hotels with Kitchenettes in Morro Bay
- Hotels with smoking rooms in Morro Bay
- La Quinta Inn & Suites Hotels in Morro Bay
- Luxury Hotels in Morro Bay
- Motel 6 Hotels in Morro Bay
- Oceanfront Hotels in Morro Bay
- Pet Friendly Hotels in Morro Bay
- Romantic Getaways & Hotels in Morro Bay
- Ski Resorts and in Morro Bay
- Spa Resorts & in Morro Bay
- Hotel Wedding Venues Hotels in Morro Bay
- Winery Hotels in Morro Bay
- Wyndham Hotels in Morro Bay
- Morro Bay Hotels
- Motels in Morro Bay
- Vacation Homes in Morro Bay
- San Luis Obispo Wine Country Hotels
- Hotels near Avila Beach Golf Resort
- Hotels near The Giant Chessboard
- Hotels near Morro Rock
- Hotels near Central Coast Aquarium
- Hotels near Montaña de Oro State Park
- Hotels near Irish Hills Natural Reserve
- Hotels near Johnson Ranch Open Space
- Hotels near Alex G. Spanos Stadium
- Hotels near Bob Jones City to Sea Bike Trail
- Avila Beach Hotels
- Hotels near Dairy Creek Golf Course
- Hotels near Morro Coast Audubon Society Sweet Springs Nature Preserve
- Rock Land Area Hotels
- Hotels near Morro Bay Golf Course
- Beach Resorts & in Baywood-Los Osos
- Hotels with Restaurants in Baywood-Los Osos
- Pacifica Hotels in Baywood-Los Osos
- Pet Friendly Hotels in Baywood-Los Osos
- Romantic Getaways & Hotels in Baywood-Los Osos
- Hotels with Shopping in Baywood-Los Osos
- Inns in Baywood-Los Osos
- Motels in Baywood-Los Osos
- Vacation Homes in Baywood-Los Osos
- Resorts in Baywood-Los Osos
- Hotels near El Chorro Regional Park
- San Luis Obispo Hotels
- Hotels near Bishop Peak Trail
- Beach Resorts & in Baywood Park
- Convention Center Hotels in Baywood Park
- Hotels with Free Parking in Baywood Park
- Pet Friendly Hotels in Baywood Park
- Romantic Getaways & Hotels in Baywood Park
- Baywood Park Hotels
- Hotels near Sunset Drive-In Theatre
- Hotels near Laguna Lake Park






