Explore top 2025 5 Star Hotels in James Island

Name: Wentworth Mansion
Price range: $516 total

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Top James Island 5 Star hotels

The Charleston Place

205 Meeting Street, Charleston, SC

Fully refundableReserve now, pay when you stay

$427 nightly

$487 total

Sep 7 - Sep 8

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate complimentary bicycles, kid-friendly dining, ...

Hotel Bennett

404 King St, Charleston, SC

Fully refundableReserve now, pay when you stay

$471 nightly

$537 total

Sep 7 - Sep 8

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...

The Dewberry Charleston

334 Meeting Street, Charleston, SC

Fully refundableReserve now, pay when you stay

$401 nightly

$457 total

Sep 7 - Sep 8

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Valet ...

The Sanctuary at Kiawah Island Golf Resort

1 Sanctuary Beach Drive, Kiawah Island, SC

$655 nightly

$740 total

Sep 7 - Sep 8

Total with taxes and fees

This luxury resort features a golf course, a full-service spa, and 3 restaurants. There's fun for all ages with a children's club and a playground, and families ...

The Dunlin Auberge Resorts Collection

6000 Kiawah River Dr, Johns Island, SC

Fully refundableReserve now, pay when you stay

$644 nightly

$722 total

Sep 28 - Sep 29

Total with taxes and fees

A full-service spa, 3 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. There's fun for all ages with a children's club and a children's ...

Zero George Street

0 George St, Charleston, SC

Fully refundableReserve now, pay when you stay

$369 nightly

$421 total

Sep 8 - Sep 9

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

Wentworth Mansion

149 Wentworth St, Charleston, SC

$452 nightly

$516 total

Sep 7 - Sep 8

Total with taxes and fees

This luxury hotel features a full-service spa and a restaurant. Traveling on business? Take advantage of the free WiFi in public areas, conference space, and ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

James Island Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in James Island to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. James Island 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in James Island before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.