Explore top 2025 4 Star Hotels in Ohio River Valley

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Top Ohio River Valley 4 Star hotels

Sonesta Columbus Downtown

Sonesta Columbus Downtown

4 out of 5
33 E Nationwide Blvd, Columbus, OH
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $202 total per night from Oct 19 to Oct 20
$202 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
8.4/10 Very Good! (1,459 reviews)
"We were not aware of all the construction that was being done"

Reviewed on Sep 23, 2025

Opens in a new windowSonesta Columbus Downtown
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street, Louisville, KY
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from Sep 30 to Oct 1
$161 total
Sep 30 - Oct 1
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.8/10 Excellent! (3,642 reviews)
"Hated that the pool was closed for the season and there wasnt a microwave in the room, but room service was fast and amazing, the room was HUGE and super clean, everyone was so nice!! Already talking about booking again!!"

Reviewed on Sep 24, 2025

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
I Hotel And Illinois Conference Center

I Hotel And Illinois Conference Center

4 out of 5
1900 South First Street, Champaign, IL
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $134 total per night from Oct 12 to Oct 13
$134 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
9.6/10 Exceptional! (1,822 reviews)
"We loved the convenience of being an easy drive to our concert at the Virginia Theater last night (a Monday) and still close to visit campus town. We plan to stay here again, possibly for Ebertfest."

Reviewed on Sep 23, 2025

Opens in a new windowI Hotel And Illinois Conference Center
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

4 out of 5
35 W 5th St, Cincinnati, OH
$135 nightly
The price is $161 total per night from Oct 12 to Oct 13
$161 total
Oct 12 - Oct 13
Total with taxes and fees
This historic hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
7.8/10 Good! (1,212 reviews)
"The hotel was lovely inside. Very nice restaurant called the 1931. The room was nice. The only issue was the pillows were worn."

Reviewed on Sep 24, 2025

Opens in a new windowHilton Cincinnati Netherland Plaza
Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

4 out of 5
151 West Fifth Street, Cincinnati, OH
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $172 total per night from Oct 19 to Oct 20
$172 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.8/10 Excellent! (1,553 reviews)
A Jazza-lishes stay
"Very clean rooms! the staff in the restaurant were very friendly and cordial. The lobby itself is very retro and chic. The king bed my wife and I slept in was so comfortable! And our view we had on the 21st floor was Jaw dropping :) perfect for going to a football/baseball game and exploring local ..."

Reviewed on Sep 20, 2025

Opens in a new windowHyatt Regency Cincinnati
Wyndham Columbus

Wyndham Columbus

4 out of 5
175 Hutchinson Ave, Columbus, OH
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $64 total per night from Sep 30 to Oct 1
$64 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and WiFi in public ...
6.8/10 (1,622 reviews)
"i love this place so safe and soooo clean"

Reviewed on Sep 25, 2025

Opens in a new windowWyndham Columbus
Hilton Columbus Downtown

Hilton Columbus Downtown

4 out of 5
402 North High Street, Columbus, OH
$169 nightly
The price is $200 total per night from Oct 5 to Oct 6
$200 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9.2/10 Wonderful! (1,368 reviews)
"Very beautiful hotel clean. I Love My bed!!!"

Reviewed on Sep 25, 2025

Opens in a new windowHilton Columbus Downtown
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street, Louisville, KY
$199 nightly
The price is $234 total per night from Oct 19 to Oct 20
$234 total
Oct 19 - Oct 20
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.2/10 Wonderful! (1,623 reviews)
"Upscale stay, beautiful property, and great location! We were able to walk to so many great restaurants and the hotel really made a great experience for our first time in Louisville. Will be returning!"

Reviewed on Sep 21, 2025

Opens in a new windowOmni Louisville Hotel
Ironworks Hotel Indy

Ironworks Hotel Indy

4 out of 5
2721 E 86th Street, Indianapolis, IN
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $203 total per night from Sep 29 to Sep 30
$203 total
Sep 29 - Sep 30
Total with taxes and fees
This smoke-free hotel's 4 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Traveling on business? Take advantage of the business ...
9.6/10 Exceptional! (1,636 reviews)
"Fabulous and beautiful! Service was top rate!! Just a wonderful beautiful hotel"

Reviewed on Sep 27, 2025

Opens in a new windowIronworks Hotel Indy
The Westin Cincinnati

The Westin Cincinnati

4 out of 5
21 E 5th St, Cincinnati, OH
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $161 total per night from Sep 29 to Sep 30
$161 total
Sep 29 - Sep 30
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. ...
8.4/10 Very Good! (1,075 reviews)
"great room overlooking park. free bus shuttle just around corner. fast elevators to our 9 th floor"

Reviewed on Sep 23, 2025

Opens in a new windowThe Westin Cincinnati
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4 Star Hotels Ohio River Valley

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Ohio River Valley 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Ohio River Valley will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Ohio River Valley, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Ohio River Valley hotel reviews by fellow wanderers