Book Hotels in Ohio River Valley

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Sep 26 - Sep 27
Tomorrow
Sep 27 - Sep 28
This weekend
Sep 26 - Sep 28
Next weekend
Oct 3 - Oct 5

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Ohio River Valley hotels

Ironworks Hotel Indy

Ironworks Hotel Indy

4 out of 5
2721 E 86th Street, Indianapolis, IN
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $204 total per night from Sep 28 to Sep 29
$204 total
Sep 28 - Sep 29
Total with taxes and fees
This smoke-free hotel's 4 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Traveling on business? Take advantage of the business ...
"Everything was great! When we come to Indy, this is where we like to stay!!!! We would definitely recommend to others!"

Reviewed on Sep 21, 2025

Opens in a new windowIronworks Hotel Indy
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street, Louisville, KY
$199 nightly
The price is $234 total per night from Oct 19 to Oct 20
$234 total
Oct 19 - Oct 20
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
"Upscale stay, beautiful property, and great location! We were able to walk to so many great restaurants and the hotel really made a great experience for our first time in Louisville. Will be returning!"

Reviewed on Sep 21, 2025

Opens in a new windowOmni Louisville Hotel
Courtyard by Marriott Indianapolis Downtown

Courtyard by Marriott Indianapolis Downtown

3 out of 5
601 West Washington Street, Indianapolis, IN
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $170 total per night from Oct 26 to Oct 27
$170 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Connected to the conference center"

Reviewed on Sep 25, 2025

Opens in a new windowCourtyard by Marriott Indianapolis Downtown
Hyatt Regency Columbus

Hyatt Regency Columbus

3.5 out of 5
350 N High St, Columbus, OH
$179 nightly
The price is $211 total per night from Oct 5 to Oct 6
$211 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Nice! Wonderful stsy!"

Reviewed on Sep 22, 2025

Opens in a new windowHyatt Regency Columbus
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street, Louisville, KY
$135 nightly
The price is $159 total per night from Sep 30 to Oct 1
$159 total
Sep 30 - Oct 1
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Hated that the pool was closed for the season and there wasnt a microwave in the room, but room service was fast and amazing, the room was HUGE and super clean, everyone was so nice!! Already talking about booking again!!"

Reviewed on Sep 24, 2025

Opens in a new windowGalt House Hotel Trademark Collection by Wyndham
Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

4 out of 5
151 West Fifth Street, Cincinnati, OH
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $172 total per night from Oct 19 to Oct 20
$172 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
A Jazza-lishes stay
"Very clean rooms! the staff in the restaurant were very friendly and cordial. The lobby itself is very retro and chic. The king bed my wife and I slept in was so comfortable! And our view we had on the 21st floor was Jaw dropping :) perfect for going to a football/baseball game and exploring local ..."

Reviewed on Sep 20, 2025

Opens in a new windowHyatt Regency Cincinnati
Sonesta Columbus Downtown

Sonesta Columbus Downtown

4 out of 5
33 E Nationwide Blvd, Columbus, OH
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $200 total per night from Oct 11 to Oct 12
$200 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
"We were not aware of all the construction that was being done"

Reviewed on Sep 23, 2025

Opens in a new windowSonesta Columbus Downtown
Radisson Hotel Cincinnati Riverfront

Radisson Hotel Cincinnati Riverfront

3.5 out of 5
668 W 5th St, Covington, KY
Fully refundable
$114 nightly
The price is $128 total per night from Oct 6 to Oct 7
$128 total
Oct 6 - Oct 7
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in ...
"The wall outlets were very loose except in the bathroom area. Made it kinda difficult to plug things that we needed in."

Reviewed on Sep 22, 2025

Opens in a new windowRadisson Hotel Cincinnati Riverfront
Wyndham Columbus

Wyndham Columbus

4 out of 5
175 Hutchinson Ave, Columbus, OH
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $64 total per night from Sep 28 to Sep 29
$64 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and WiFi in public ...
"i love this place so safe and soooo clean"

Reviewed on Sep 25, 2025

Opens in a new windowWyndham Columbus
Don't see what you're looking for?
See all available properties in Ohio River Valley
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Ohio River Valley hotels

Olentangy Motor Inn

Olentangy Motor Inn

1445 Olentangy River Rd, Columbus, OH
$110 nightly
The price is $130 total per night from Oct 1 to Oct 2
$130 total
Oct 1 - Oct 2
Total with taxes and fees
9/10 Wonderful! (1,198 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Ohio River Valley hotel reviews by fellow wanderers

Courtyard by Marriott Indianapolis Downtown

Courtyard by Marriott Indianapolis Downtown

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Connected to the conference center"
A verified traveler stayed at Courtyard by Marriott Indianapolis Downtown
Courtyard by Marriott Indianapolis Downtown
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity