Explore 41 Luxury Hotels in Southern Indiana

Name: Baymont by Wyndham Corydon
Price range: $77 total
Rating: 7.4

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Best Luxury Hotels in Southern Indiana

21c Museum Hotel Louisville

700 W Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$174 nightly

$205 total

Nov 2 - Nov 3

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,013 reviews)

"Room was very clean and staff were very friendly."

Reviewed on Sep 28, 2025

The Brown Hotel

335 W Broadway, Louisville, KY

Fully refundableReserve now, pay when you stay

$169 nightly

$199 total

Oct 30 - Oct 31

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (1,087 reviews)

"The room needed a microwave and a small refrigerator other than that the room was nice staf was very friendly overall very nice"

Reviewed on Sep 27, 2025

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$137 nightly

$161 total

Nov 1 - Nov 2

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (3,660 reviews)

"Great staff, clean and comfortable space. We enjoyed our stay."

Reviewed on Sep 30, 2025

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$139 nightly

$163 total

Oct 13 - Oct 14

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...

8.8/10 Excellent! (1,047 reviews)

"Very clean"

Reviewed on Sep 30, 2025

Seelbach Hilton Louisville Downtown

500 S 4th St, Louisville, KY

Fully refundableReserve now, pay when you stay

$156 nightly

$184 total

Oct 5 - Oct 6

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...

8.6/10 Excellent! (1,010 reviews)

"Amazing experience in every way"

Reviewed on Sep 28, 2025

Baymont by Wyndham Corydon

2495 Landmark Avenue NE, Corydon, IN

Fully refundableReserve now, pay when you stay

$70 nightly

$77 total

Oct 19 - Oct 20

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...

7.4/10 Good! (1,008 reviews)

Place is okay

"The place was not as clean as we would have liked it to be. The sink where you wash your hands and brush your teeth was draining very slowly."

Reviewed on Sep 15, 2025

Econo Lodge Downtown Louisville

401 S 2nd St, Louisville, KY

Fully refundableReserve now, pay when you stay

$63 nightly

$74 total

Oct 19 - Oct 20

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the express check-out. ...

7/10 Good! (1,017 reviews)

"Older hotel, but in general seemed to be clean"

Reviewed on Sep 29, 2025

West Baden Springs Hotel

8538 W Baden Ave, West Baden Springs, IN

This luxury resort features a casino, a full-service spa, and 15 restaurants. Bring the family and enjoy the children's club, along with horse riding/rentals. ...

"The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area."

Reviewed on Dec 25, 2018

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Southern Indiana

Stellar Suites

822 E Market St, Louisville, KY

$153 nightly

$178 total

Oct 13 - Oct 14

Total with taxes and fees

9.6/10 Exceptional! (107 reviews)

Southern Indiana Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Indiana luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Indiana to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Indiana will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Indiana, and plan your next opulent escape.

Southern Indiana hotels essential information

Accommodation	1,526 hotels
Lowest Price	$74
Highest Price	$269
Popular hotels	21c Museum Hotel Louisville, West Baden Springs Hotel, The Brown Hotel, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Downtown Louisville, Seelbach Hilton Louisville Downtown, Baymont by Wyndham Corydon