Explore 41 Luxury Hotels in Southern Indiana

Name: Baymont by Wyndham Corydon
Price range: $75 total
Rating: 7.4

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Best Luxury Hotels in Southern Indiana

21c Museum Hotel Louisville

700 W Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$120 nightly

$141 total

Jan 3 - Jan 4

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,002 reviews)

The room was great! The bar was fantastic. The hotel accommodated all of my requests. My husband and I have stayed here a few times. I'm truly grateful for the kindness of the staff.

Reviewed on Dec 19, 2025

The Brown Hotel

335 W Broadway Louisville KY

Fully refundableReserve now, pay when you stay

$168 nightly

$198 total

Jan 3 - Jan 4

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (1,168 reviews)

Perfect

Reviewed on Jan 1, 2026

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$133 nightly

$157 total

Jan 6 - Jan 7

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (3,909 reviews)

The room was excellent and spacious. Staff were nice and the location in downtown was very convenient.

Reviewed on Dec 31, 2025

Embassy Suites Louisville Downtown

501 South Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$114 nightly

$134 total

Jan 18 - Jan 19

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...

8.8/10 Excellent! (1,130 reviews)

The room, staff and atmosphere were amazing. The breakfast was so so at best but everything else made up for it.

Reviewed on Dec 29, 2025

Seelbach Hilton Louisville Downtown

500 S 4th St Louisville KY

Fully refundableReserve now, pay when you stay

$148 nightly

$174 total

Jan 9 - Jan 10

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, express check-out, and ...

8.6/10 Excellent! (1,002 reviews)

Staying at The Seelbach Hotel was a wonderful experience! From the moment of walking in the lobby, it instantly felt like home! Will was working the front desk, and kindly greeted and checked me into my room. He is everything you want when it comes to customer service! He was informative when I asked ...

Reviewed on Dec 16, 2025

Baymont by Wyndham Corydon

2495 Landmark Avenue NE Corydon IN

Fully refundableReserve now, pay when you stay

$67 nightly

$75 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of ...

7.4/10 Good! (1,000 reviews)

Clean rooms, friendly staff

Reviewed on Dec 28, 2025

Econo Lodge Louisville Downtown

401 S 2nd St Louisville KY

Fully refundableReserve now, pay when you stay

$63 nightly

$74 total

Jan 15 - Jan 16

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the express check-out. ...

7/10 Good! (1,004 reviews)

Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again

Reviewed on Dec 11, 2025

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

This luxury resort features a casino, a full-service spa, and 15 restaurants. Bring the family and enjoy the children's club, along with horse riding/rentals. ...

The hotel West Baden is awesome they have 24 hour trolley that runs every 15 minutes and will take you anywhere in the area.

Reviewed on Dec 25, 2018

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More 4 star hotels in Southern Indiana

Stellar Suites

822 E Market St Louisville KY

$148 nightly

$172 total

Jan 21 - Jan 22

Total with taxes and fees

9.6/10 Exceptional! (117 reviews)

Southern Indiana Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Indiana luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Indiana to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Indiana will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Indiana, and plan your next opulent escape.

Southern Indiana hotels essential information

Accommodation	1,600 hotels
Lowest Price	$74
Highest Price	$199
Popular hotels	21c Museum Hotel Louisville, West Baden Springs Hotel, The Brown Hotel, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Louisville Downtown, Seelbach Hilton Louisville Downtown, Baymont by Wyndham Corydon

Popular Luxury Stays in Southern Indiana

5 Stars Luxury stays in Southern Indiana

Luxury stays in Southern Indiana with spa

Recent Southern Indiana Hotel Reviews By Fellow Wanderers

Hampton Inn New Albany Louisville West

5 out of 5

Posted 1 day ago

Travelocity Verified Review

"Didn’t get to get breakfast I slept straight through it. Rooms very clean staff was great "

A verified traveler stayed at Hampton Inn New Albany Louisville West

Best Western Green Tree Inn

5 out of 5

Posted 7 days ago

Travelocity Verified Review

"I enjoyed my stay a lot! Convenient location with lots of restaurant options near by. The breakfast options were wonderful, and delicious! Room was clean, bed was comfortable, and being able to park in front of my room door was so convenient. I will stay there again. "

A verified traveler stayed at Best Western Green Tree Inn