Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $141
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Top Adults Only Resorts in Florida Keys
Southernmost House - Adult Exclusive
"The lodging itself was clean and the staff great! We enjoyed our stay. All the chickens, seagulls and pigeons outside on everything was a little gross."
Reviewed on Aug 12, 2026
Casa Morada
"The entire experience was a disappointment. Expedia advertised this as CASA MORADA but we were given a room at SUNSET INN. The room as on the street, not on the water or even in the property located at the water. The actual property we stayed at was recently purchased by Casa Morada and we were not ..."
Reviewed on Aug 10, 2026
Paradise Inn Key West - Adults Only
"Excellent place, excellent staff and fantastic everything !!"
Reviewed on Aug 14, 2026
The Independent Inn - Formerly Heron House Court
"We had a wonderful stay at the Independent Inn! The new owners Emma and her husband are very nice and working very hard to upgrade all elements of the property which is still a work in progress but did not detract from our stay in the least. The location is good because you are just a 5 minute walk ..."
Reviewed on Aug 13, 2026
The Cabana Inn Key West - Adults Only
"When I go back to Key West, I will stay here again. The location was perfect and the accommodations were excellent and everyone was friendly and helpful."
Reviewed on Aug 15, 2026
The Southernmost Inn - Adults Only
"Great stay! Nothing fancy. Nice staff and well taken care"
Reviewed on Aug 15, 2026
Heron House - Adult Only
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Find 5-Star Hotels in Florida Keys
Cheeca Lodge & Spa
Search All-Inclusive Hotels in Florida Keys
Casa Marina Key West, Curio Collection by Hilton
Popular Adults Only Stays in Florida Keys
Book a stay at the best Florida Keys adult only resorts
How can I find the best adults-only resorts in Florida Keys?
Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.
How can I find adults-only all-inclusive resorts in Florida Keys?
Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.
How much do Florida Keys adults-only hotels cost?
Prices start at just $141 a night, going up to $322 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.
When is the best time for an adult getaway to Florida Keys?
In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.
Are there any cheap couples’ resorts in Florida Keys?
To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.
How can I find adults-only spa resorts in Florida Keys?
Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.
What are some great things to do in Florida Keys for adults?
Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.
How can I find the best Florida Keys adults-only hotel deals?
With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.
Can I get free cancellation on my adults only hotel in Florida Keys?
Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.
Why should I book my adults only resort in Florida Keys with Travelocity?
With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.
Recent Florida Keys hotel reviews by fellow wanderers
Cheeca Lodge & Spa
"Balcony curtains need to be changed."