Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $233
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Top Adults Only Resorts in Florida Keys
Alexander's Guesthouse - Adult Exclusive
"Loved the amenities provided at Alexander’s! Awesome spot. All guests we encountered were extremely friendly."
Reviewed on Oct 30, 2026
Southernmost House - Adult Exclusive
"Great place! Very peaceful and quiet. walking distance to duval street. Would definitely stay there again"
Reviewed on Oct 26, 2026
Paradise Inn Key West - Adults Only
"Great place. Great Key West character. Secluded yet close enough to walk to most things. Pool was often crowded and in need of a little TLC but staff was very friendly and we thoroughly enjoyed our week long stay."
Reviewed on Nov 2, 2026
Heron House - Adult Only
"Place is amazing. Staff was very helpful. Location is great and within 5 min walking distance of anything around in Old Key West"
Reviewed on Nov 1, 2026
The Cabana Inn Key West - Adults Only
"Parking is easy and the staff was helpful and welcoming. We loved the value for the room we got. We booked the owner’s suite and we are excited to come back one day. We enjoyed the happy hour and breakfast. Just a warning the chickens and roosters will wake you up early! But it’s part of the Key ..."
Reviewed on Nov 1, 2026
The Southernmost Inn - Adults Only
The Independent Inn-Adults only
Casa Morada
Find 5-Star Hotels in Florida Keys
Cheeca Lodge & Spa
Search All-Inclusive Hotels in Florida Keys
Casa Marina Key West, Curio Collection by Hilton
Popular Adults Only Stays in Florida Keys
Book a stay at the best Florida Keys adult only resorts
How can I find the best adults-only resorts in Florida Keys?
Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.
How can I find adults-only all-inclusive resorts in Florida Keys?
Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.
How much do Florida Keys adults-only hotels cost?
Prices start at just $233 a night, going up to $811 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.
When is the best time for an adult getaway to Florida Keys?
In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.
Are there any cheap couples’ resorts in Florida Keys?
To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.
How can I find adults-only spa resorts in Florida Keys?
Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.
What are some great things to do in Florida Keys for adults?
Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.
How can I find the best Florida Keys adults-only hotel deals?
With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.
Can I get free cancellation on my adults only hotel in Florida Keys?
Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.
Why should I book my adults only resort in Florida Keys with Travelocity?
With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.
Recent Florida Keys hotel reviews by fellow wanderers
Cheeca Lodge & Spa
"Food was excellent and staff was extremely friendly. The room could have been a little better. The floors were sandy but the room was otherwise clean"
Hawks Cay Resort
"This resort never disappoints! Love the property, amenities, and the adult pool"