Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $142

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Top Adults Only Resorts in Florida Keys

 Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

1118 Fleming St, Key West, FL
$268 nightly
The price is $302 total per night from Jul 28 to Jul 29
$302 total
Jul 28 - Jul 29
Total includes taxes and fees
This hotel features an outdoor pool and a hot tub. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A business center, ...
9.8/10 Exceptional! (102 reviews)
"The staff are stellar treat you with utmost respect and go out of there way to accommodate guests. I’ve been staying here for years and will definitely come back. It’s like coming home to family every single time. Keep up the great work guys you’re killing it!! xo"

Reviewed on Jul 4, 2025

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Southernmost House

Southernmost House

1400 Duval Street, Key West, FL
$266 nightly
The price is $299 total per night from Aug 5 to Aug 6
$299 total
Aug 5 - Aug 6
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.2/10 Wonderful! (1,000 reviews)
"Magical Like time traveling but with ice cold AC and Netflix :)"

Reviewed on Jul 17, 2025

Southernmost House
Casa Morada

Casa Morada

136 Madeira Road, Islamorada, FL
$284 nightly
The price is $320 total per night from Jul 29 to Jul 30
$320 total
Jul 29 - Jul 30
Total includes taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Enjoy a day at the beach kayaking, or relax with beach umbrellas. There's no skimping ...
9.2/10 Wonderful! (403 reviews)
"I have been coming here for years! With my daughter and or my husband We love the surroundings the tranquility of it. The staff is wonderful as well Sam, Eric friendly and lovely Great buffet in the am always inviting We Will continue our tradition at the Casa Morada"

Reviewed on Jul 17, 2025

Casa Morada
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

819 Simonton Street, Key West, FL
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $182 total per night from Jul 24 to Jul 25
$182 total
Jul 24 - Jul 25
Total includes taxes and fees
This hotel features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
9/10 Wonderful! (1,009 reviews)
"❤️"

Reviewed on Jul 21, 2025

Paradise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St, Key West, FL
$151 nightly
The price is $166 total per night from Aug 11 to Aug 12
$166 total
Aug 11 - Aug 12
Total includes taxes and fees
This bed & breakfast features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A ...
9/10 Wonderful! (1,138 reviews)
"Location was great!! Walking distance to BOTH the north and south sides!! Property was built in the late 1890's so it has awesome charm!!"

Reviewed on Jul 16, 2025

Heron House - Adult Only
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West, FL
$129 nightly
The price is $142 total per night from Jul 29 to Jul 30
$142 total
Jul 29 - Jul 30
Total includes taxes and fees
This guesthouse features an outdoor pool and a rooftop terrace. WiFi in public areas is free. A terrace, a garden, and luggage storage are also on offer.
8.8/10 Excellent! (1,004 reviews)
"Roman and the staff were very helpful. Herron House Court is very convenient to pretty much everything. There are mini fridges in the rooms so bring your own bottles of water, but don’t save leftovers as there are no microwaves."

Reviewed on Jul 19, 2025

Heron House Court - Adult Only
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

413 Applerouth Lane, Key West, FL
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $169 total per night from Jul 28 to Jul 29
$169 total
Jul 28 - Jul 29
Total includes taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
8.8/10 Excellent! (1,006 reviews)
"Perfect spot righ next to Duval St. where all the action is!!"

Reviewed on Jul 22, 2025

The Cabana Inn Key West - Adults Only
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

525 United Street, Key West, FL
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $156 total per night from Jul 29 to Jul 30
$156 total
Jul 29 - Jul 30
Total includes taxes and fees
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and ...
8.2/10 Very Good! (1,132 reviews)
"Good option if the price is right. The pool area makes this place a special one. You can bring your own booze which is cool. The lady at the front desk was extremely helpful and polite. We loved her vibe . I think her name was Tamisha"

Reviewed on Jul 20, 2025

The Southernmost Inn - Adults Only
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Book a stay at the best Florida Keys adult only resorts

How can I find the best adults-only resorts in Florida Keys?


Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.


How can I find adults-only all-inclusive resorts in Florida Keys?


Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.


How much do Florida Keys adults-only hotels cost?


Prices start at just $142 a night, going up to $434 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.


When is the best time for an adult getaway to Florida Keys?


In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.


Are there any cheap couples’ resorts in Florida Keys?


To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.


How can I find adults-only spa resorts in Florida Keys?


Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.


What are some great things to do in Florida Keys for adults?


Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.


How can I find the best Florida Keys adults-only hotel deals?


With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.  


Can I get free cancellation on my adults only hotel in Florida Keys?


Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.  


Why should I book my adults only resort in Florida Keys with Travelocity?


With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.


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