Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $169
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Top Adults Only Resorts in Florida Keys

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
"This place is amazing! The people are so, so friendly and helpful!"
Reviewed on Jun 1, 2026

Southernmost House - Adult Exclusive
"The staff were extremely welcoming, and the property had a wonderful view and nice cool air conditioning. The shower was massive and really nice. Recommended!"
Reviewed on Jul 3, 2026

Casa Morada
"My husband and I stayed here for a quick weekend getaway and I am so glad we did! The rooms were very clean, the staff were all friendly and helpful and the property is beautiful! We loved that it was a small resort and tucked away from the main road, which made it comfortable and quiet. We enjoyed ..."
Reviewed on Jul 3, 2026

Paradise Inn Key West - Adults Only
"Great boutique hotel close to every thing. Very impressed with the king suite it was so large and overlooked the pool. Nicely updated. Air conditioning was ice cold worked very well. Great happy hour with wine cheese and crackers. The girl at the front office goes out of her way to make sure you ..."
Reviewed on Jul 1, 2026

Heron House - Adult Only
"AMAZING place. Super well taken care of, roo.s are spacious and beautiful A(I stayed in room 10). The staff was super helpful and Greg was a Great. Just a few blocks from the Walgreens on Duval but way from all the craziness. Adults only makes a difference for sure! Will definetly return"
Reviewed on Jun 29, 2026

The Independent Inn - Locally Owned
"Staff"
Reviewed on Jul 1, 2026

The Cabana Inn Key West - Adults Only
"From the moment we checked into the moment we left the staff was amazing extremely kind and very accommodating. The rooms were large. The pool area was perfect. Everything was just a great experience."
Reviewed on Jul 3, 2026

The Southernmost Inn - Adults Only
"We were told we would have housecleaning every other day, we did not get it even one day. We had to keep going to the desk to get new towels, toilet paper soap. We even hung the sign on the door stating that we wanted it cleaned, and it was never cleaned. They messed up our parking and when we returned ..."
Reviewed on Jul 3, 2026
Find 5-Star Hotels in Florida Keys

Cheeca Lodge & Spa
Search All-Inclusive Hotels in Florida Keys

Casa Marina Key West, Curio Collection by Hilton
Popular Adults Only Stays in Florida Keys
Book a stay at the best Florida Keys adult only resorts
How can I find the best adults-only resorts in Florida Keys?
Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.
How can I find adults-only all-inclusive resorts in Florida Keys?
Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.
How much do Florida Keys adults-only hotels cost?
Prices start at just $169 a night, going up to $359 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.
When is the best time for an adult getaway to Florida Keys?
In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.
Are there any cheap couples’ resorts in Florida Keys?
To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.
How can I find adults-only spa resorts in Florida Keys?
Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.
What are some great things to do in Florida Keys for adults?
Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.
How can I find the best Florida Keys adults-only hotel deals?
With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.
Can I get free cancellation on my adults only hotel in Florida Keys?
Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.
Why should I book my adults only resort in Florida Keys with Travelocity?
With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.
Recent Florida Keys hotel reviews by fellow wanderers

Hawks Cay Resort
"Hawks Cay was a very pleasant stay. Our 2 BR villa was the right size for our family, and its central location made day trips to other keys a breeze."








