Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $130
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Top Adults Only Resorts in Florida Keys
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
"We had such a great stay, nice property, Great location , the staff was helpful, friendly and fantastic! Delicious breakfast included … we really loved this place and we are looking forward to come back!"
Reviewed on Sep 21, 2026
Casa Morada
"Very helpful staff and great location"
Reviewed on Sep 22, 2026
Heron House - Adult Only
"It was all about location for me"
Reviewed on Sep 23, 2026
The Independent Inn - Formerly Heron House Court
"I would highly recommend the Independant Inn. The staff was exceptionally helpful and went above and beyond to ensure that our stay and experience in Key West were everything we hoped it would be. The property is clean and well maintained and just as inviting as it looks in the photos. If we have ..."
Reviewed on Sep 22, 2026
The Cabana Inn Key West - Adults Only
"Great stay. Clean and well Maintained. Friendly staff."
Reviewed on Sep 21, 2026
The Southernmost Inn - Adults Only
"The rooms are very clean it’s very quiet and the pools are nice and clean very enjoyable stay"
Reviewed on Sep 22, 2026
Paradise Inn Key West - Adults Only
Southernmost House - Adult Exclusive
Find 5-Star Hotels in Florida Keys
Cheeca Lodge & Spa
Search All-Inclusive Hotels in Florida Keys
Casa Marina Key West, Curio Collection by Hilton
Popular Adults Only Stays in Florida Keys
Book a stay at the best Florida Keys adult only resorts
How can I find the best adults-only resorts in Florida Keys?
Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.
How can I find adults-only all-inclusive resorts in Florida Keys?
Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.
How much do Florida Keys adults-only hotels cost?
Prices start at just $130 a night, going up to $512 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.
When is the best time for an adult getaway to Florida Keys?
In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.
Are there any cheap couples’ resorts in Florida Keys?
To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.
How can I find adults-only spa resorts in Florida Keys?
Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.
What are some great things to do in Florida Keys for adults?
Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.
How can I find the best Florida Keys adults-only hotel deals?
With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.
Can I get free cancellation on my adults only hotel in Florida Keys?
Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.
Why should I book my adults only resort in Florida Keys with Travelocity?
With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.
Recent Florida Keys hotel reviews by fellow wanderers
Hawks Cay Resort
"The resort was beautiful. The food was good but pricey. We loved having the option to have the food/drinks delivered by the pool. The bed was comfortable and the Cabana room was very convenient to have right next to the adult pool area. Our only issue was the AC fluctuated a bit and a few nights it got too cold (one of our neighbors room was way too warm so it could have been worse). And the hot water wasn't really hot enough to take a decent shower. But overall we felt these were minor issues and the staff was so amazing we felt well taken care of otherwise."