Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $153

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Top Adults Only Resorts in Florida Keys

 Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

1118 Fleming St, Key West, FL
$201 nightly
The price is $226 total per night from Jul 15 to Jul 16
$226 total
Jul 15 - Jul 16
Total includes taxes and fees
This hotel features an outdoor pool and a hot tub. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A business center, ...
9.8/10 Exceptional! (102 reviews)
"The staff are stellar treat you with utmost respect and go out of there way to accommodate guests. I’ve been staying here for years and will definitely come back. It’s like coming home to family every single time. Keep up the great work guys you’re killing it!! xo"

Reviewed on Jul 4, 2025

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Southernmost House

Southernmost House

1400 Duval Street, Key West, FL
$269 nightly
The price is $303 total per night from Jul 22 to Jul 23
$303 total
Jul 22 - Jul 23
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Unwind with a drink at the poolside bar and enjoy perks like free continental breakfast ...
9.2/10 Wonderful! (1,007 reviews)
"Great historical place to stay. Staff is amazing. Couldn’t ask for more."

Reviewed on Jul 10, 2025

Southernmost House
Casa Morada

Casa Morada

136 Madeira Road, Islamorada, FL
$246 nightly
The price is $277 total per night from Jul 13 to Jul 14
$277 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Enjoy a day at the beach kayaking, or relax with beach umbrellas. There's no skimping ...
9.2/10 Wonderful! (400 reviews)
"Charming hotel with beautiful views!"

Reviewed on Jul 1, 2025

Casa Morada
Paradise Inn Key West - Adults Only

Paradise Inn Key West - Adults Only

819 Simonton Street, Key West, FL
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $165 total per night from Jul 21 to Jul 22
$165 total
Jul 21 - Jul 22
Total includes taxes and fees
This hotel features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
9/10 Wonderful! (1,001 reviews)
"Nice rooms, decent pool."

Reviewed on Jun 29, 2025

Paradise Inn Key West - Adults Only
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St, Key West, FL
$139 nightly
The price is $153 total per night from Jul 13 to Jul 14
$153 total
Jul 13 - Jul 14
Total includes taxes and fees
This bed & breakfast features an outdoor pool and a rooftop terrace. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A ...
9/10 Wonderful! (1,148 reviews)
"We had a great experience here, I highly recommend and I will be staying here again. Very private and quiet, rooms were so cute! Gentlemen at the front was so welcoming and great!"

Reviewed on Jul 11, 2025

Heron House - Adult Only
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West, FL
$154 nightly
The price is $170 total per night from Aug 11 to Aug 12
$170 total
Aug 11 - Aug 12
Total includes taxes and fees
This guesthouse features an outdoor pool and a rooftop terrace. WiFi in public areas is free. A terrace, a garden, and luggage storage are also on offer.
8.8/10 Excellent! (1,004 reviews)
"The staff was awesome! Great location! Rooms were very clean! Nice pool area!"

Reviewed on Jul 10, 2025

Heron House Court - Adult Only
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

413 Applerouth Lane, Key West, FL
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $190 total per night from Jul 31 to Aug 1
$190 total
Jul 31 - Aug 1
Total includes taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
8.6/10 Excellent! (1,008 reviews)
Best Inn in Key West
"Outstanding! We have stayed at many different inns in Key West, and the Cabana Inn, was by far, the very best! Patrick was welcoming and attentive, and the rooms spacious and comfortable, and although only a few minutes walk to Duvall, was nice and quiet. Excellent breakfast, coffee available at ..."

Reviewed on Jul 9, 2025

The Cabana Inn Key West - Adults Only
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

525 United Street, Key West, FL
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $169 total per night from Jul 13 to Jul 14
$169 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel's 2 outdoor pools and hot tub are among the featured amenities. Enjoy the free continental breakfast each morning. Self parking, a coffee shop, and ...
8/10 Very Good! (1,123 reviews)
"Nice quit location right off Duval Street with super clean pools and bars around it."

Reviewed on Jul 11, 2025

The Southernmost Inn - Adults Only
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Book a stay at the best Florida Keys adult only resorts

How can I find the best adults-only resorts in Florida Keys?


Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.


How can I find adults-only all-inclusive resorts in Florida Keys?


Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.


How much do Florida Keys adults-only hotels cost?


Prices start at just $153 a night, going up to $403 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.


When is the best time for an adult getaway to Florida Keys?


In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.


Are there any cheap couples’ resorts in Florida Keys?


To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.


How can I find adults-only spa resorts in Florida Keys?


Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.


What are some great things to do in Florida Keys for adults?


Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.


How can I find the best Florida Keys adults-only hotel deals?


With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.  


Can I get free cancellation on my adults only hotel in Florida Keys?


Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.  


Why should I book my adults only resort in Florida Keys with Travelocity?


With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.


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