Find & Compare 40 Adults-Only Hotels & Resorts in Florida Keys With Rates at from $159
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Top Adults Only Resorts in Florida Keys
Alexander's Guesthouse - Adult Exclusive
"The room is super clean"
Reviewed on Sep 28, 2026
Casa Morada
"It was clean, and the staff were lovely. However it’s advertised as a beach front resort, there are some rooms away from the main property which are on the water but the main property is on the main road and is basically a motel. Not at all how it appears on the pictures. It was expensive but we ..."
Reviewed on Sep 26, 2026
Paradise Inn Key West - Adults Only
"Very cute and clean property. The only thing I didn’t like was the fee for parking our rented golf cart in property."
Reviewed on Sep 30, 2026
Heron House - Adult Only
"Very nice property. Large, clean rooms. Bathroom was ok. Blinds didn't work, need replacement. Overall great property, great price, great location."
Reviewed on Sep 29, 2026
The Independent Inn - Formerly Heron House Court
"Great little spot for a quick trip to Key West. Nicely located and very walkable. We enjoyed the spacious room and very comfortable pool. Room was very clean if some what a little “lived in”. Could use a bit of a refresh but great value for the price! Would definitely stay again!"
Reviewed on Sep 27, 2026
The Cabana Inn Key West - Adults Only
"Room was great breakfast was plentiful and staff great. Would definitely recommend and stay there again"
Reviewed on Sep 29, 2026
The Southernmost Inn - Adults Only
"The rooms were extraordinarily small. Although they were clean. The bathroom, had cracks in the walls, cracks in the bathroom tiles, and mold and mildew on the bottom of the shower stall. There was a hole in the bathroom door like somebody had pushed the hole through it. The shades on the windows ..."
Reviewed on Sep 29, 2026
Southernmost House - Adult Exclusive
Find 5-Star Hotels in Florida Keys
Cheeca Lodge & Spa
Search All-Inclusive Hotels in Florida Keys
Casa Marina Key West, Curio Collection by Hilton
Popular Adults Only Stays in Florida Keys
Book a stay at the best Florida Keys adult only resorts
How can I find the best adults-only resorts in Florida Keys?
Enter your travel dates, hit search, and click on the hotel resorts filter to compare prices, ratings, and genuine customer reviews from fantastic Florida Keys adults-only resorts.
How can I find adults-only all-inclusive resorts in Florida Keys?
Click on our all-inclusive filter to see the latest deals on an enticing selection of adults only all-inclusive resorts and hotels in Florida Keys. It’s that simple.
How much do Florida Keys adults-only hotels cost?
Prices start at just $159 a night, going up to $588 for luxury adults-only accommodation. Prices and availability are subject to change. Additional terms may apply.
When is the best time for an adult getaway to Florida Keys?
In , there’s loads going on and a great atmosphere. A super-popular time for a romantic adult-only getaway is Valentine's weekend in Florida Keys.
Are there any cheap couples’ resorts in Florida Keys?
To find cheaper accommodation in Florida Keys, order your search results by lowest price to see wallet friendlier stays first. You can use the budget filter, too. If your travel dates are flexible, visit in , when prices tend to be lower.
How can I find adults-only spa resorts in Florida Keys?
Click on our spa filter under amenities on your search results page to see the spa resorts and hotels that whisk you away to a world of pampering and relaxation—just as you deserve.
What are some great things to do in Florida Keys for adults?
Whether you’re taking a break from work, family, kids, or just the rigor of daily life, an adults-only break is the perfect opportunity to relax. Explore Florida Keys by booking an excursion, chill by the pool with your loved one, and enjoy romantic cocktails and evening meals by candlelight.
How can I find the best Florida Keys adults-only hotel deals?
With Travelocity, you can see the latest deals simply by entering your travel dates and hitting search. Use the budget filter to narrow down accommodation in your price range, check out our customer ratings to compare deals, too, and when you download the free Travelocity appOpens in a new window, you also get great member discounts.
Can I get free cancellation on my adults only hotel in Florida Keys?
Many adults only hotels in Florida Keys offer free cancellation. Canceling a booking is simple: Log into your My TripsOpens in a new window page and go to your itinerary to see your options. Visit our Customer Support PortalOpens in a new window for more details. If you booked a property offering free cancellation or took up our reserve now, pay later offer then you may not be out of pocket either.
Why should I book my adults only resort in Florida Keys with Travelocity?
With Travelocity, you get a fantastic selection of Florida Keys adults only hotel and resort deals in just one click. You can save even more when you bundle your flights and car rental together, too. So, escape for an unforgettable adults-only vacation and book your dream hotel today.
Recent Florida Keys hotel reviews by fellow wanderers
Cheeca Lodge & Spa
"The room was a little loud from the A/C unit but great stay"