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Top hotels in Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $194 total per night from Nov 17 to Nov 18
$194 total
per night
Nov 17 - Nov 18
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Very nice hotel. Clean, friendly Front Desk Staff, food.

Reviewed on Nov 8, 2025

Opens in a new windowLegacy Resort Hotel & Spa
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $89 total per night from Nov 23 to Nov 24
$89 total
per night
Nov 23 - Nov 24
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...
Not spotless

Reviewed on Nov 8, 2025

Opens in a new windowKings Inn San Diego
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $119 total per night from Dec 1 to Dec 2
$119 total
per night
Dec 1 - Dec 2
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Great location

Reviewed on Nov 9, 2025

Opens in a new windowHampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $136 total per night from Nov 19 to Nov 20
$136 total
per night
Nov 19 - Nov 20
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Didnt eat breakfast buffet cost to expensive.

Reviewed on Nov 7, 2025

Opens in a new windowSheraton Mission Valley San Diego Hotel
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $112 total per night from Dec 1 to Dec 2
$112 total
per night
Dec 1 - Dec 2
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Pool area is beautiful! 10’ pool and huge jacuzzi. Tropical environment. Great food. The Reef Lounge is awesome. Fire pits by the pool. Clean, comfy rooms. We stay-cation monthly and they have better beds than most. Every thing is close by.

Reviewed on Nov 10, 2025

Opens in a new windowHandlery Hotel
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $127 total per night from Nov 26 to Nov 27
$127 total
per night
Nov 26 - Nov 27
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
Great experience. Excellent customer service! We enjoyed the indoor pool.

Reviewed on Nov 9, 2025

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $131 total per night from Nov 19 to Nov 20
$131 total
per night
Nov 19 - Nov 20
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Yes

Reviewed on Nov 12, 2025

Opens in a new windowHilton San Diego Mission Valley
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $119 total per night from Nov 23 to Nov 24
$119 total
per night
Nov 23 - Nov 24
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free full breakfast ...
Front desk staff was super helpful to switch a room for us

Reviewed on Nov 9, 2025

Opens in a new windowBest Western Inn & Suites San Diego – Zoo/SeaWorld Area
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is $102 total per night from Nov 16 to Nov 17
$102 total
per night
Nov 16 - Nov 17
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
People hanging outside very late

Reviewed on Nov 12, 2025

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mission Valley Hotel Guide\n

Hotels in Mission Valley, San Diego, put you in the heart the city's Old Town, a place with an unparalleled role in the history of the American West. It's the site of the first Spanish settlement in California, where some of the oldest buildings in the state still stand, but today's Mission Valley also draws in visitors as a prime entertainment and shopping district. Find a San Diego flight today for a journey into California history.

Mission Valley

The ruins that remain of the Presidio of San Diego, which was established in 1769, are in Presidio Park, a four-acre green space and National Historic Landmark overlooking Mission Valley. The original site is now marked by the Junipero Serra Museum, where you can learn about this earliest of all Spanish settlements in the state. Mission Valley hotels also put you close to the Old Town San Diego Historic Park, where preserved historic buildings from 1820 to 1870 show you what life was like in San Diego long before it became a destination for beach-seeking tourists. See stores, a stable, a schoolhouse, a blacksmith's shop, and a newspaper office. This desirable area of San Diego doesn't just appeal to history buffs. Book a vacation to San Diego for the whole family and take the kids to SeaWorld, located on the edge of Mission Valley. The valley ends at Mission Bay, a saltwater lagoon surrounded by the largest aquatic park in the country. Wander its pedestrian pathways, or take to the water with a sailing, jet-skiing, or wakeboarding excursion. And you can add shopping to your itinerary: Westfield Mission Valley and Fashion Valley Mall are just two of the area's major retail destinations.

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