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Top Los Osos hotels

Quality Suites Downtown San Luis Obispo
Made to order breakfast was average. Scrambled eggs were not real eggs and served at room temperature not hot. Very disappointing.
Reviewed on Apr 18, 2026

SeaCrest OceanFront Hotel
This place is just breathtaking. The view is amazing.
Reviewed on Apr 20, 2026

Madonna Inn
Great.
Reviewed on Apr 20, 2026

Oxford Suites Pismo Beach
the rooms were beautiful, the staff was nice & attentive breakfast was delicious. my family and i will definitely be stay here again. 10/10 recommended to stay here!
Reviewed on Apr 21, 2026

Cottage Inn By The Sea
Great hotel with awesome amenities!
Reviewed on Apr 20, 2026

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Room was clean, EXCEPT for the toenail clippings in the carpet at the end of the bed. We informed them of this. They apologized, and said they would take care of it. They cleaned the room EXCEPT THEY DID NOT VACUUM. Day 2 toenails still there. I complained . They were sorry,will take care of it. ...
Reviewed on Apr 21, 2026

Spyglass Inn
Wonderful location and excellent service
Reviewed on Apr 20, 2026

Best Western Casa Grande Inn
This is our third time staying at this motel, and we will most likely stay here again. It is convenient to the highway, serves breakfast and is family friendly.
Reviewed on Apr 20, 2026

Edgewater Inn And Suites
Sand on the floor, bathroom was dirty, scratched and scuffed up… not worth the price
Reviewed on Apr 21, 2026
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Los Osos Hotel & Travel Guide\n
If you're not sure how to begin planning your San Luis Obispo trip, rest assured, because there's no end of perfect accommodation options in Los Osos. Thanks to our handy accommodation guide, you can explore 30 rooms within 6 miles (10 kilometers) of Los Osos's downtown region.
The Sea Pines is a great option for your stay because it is one of the most ideally located options, one of only a small number of choices that are within walking distance of the Los Osos central area.
The Dolphin Bay Resort And Spa is approximately 12 miles (19 kilometers) outside of the center of Los Osos. Another alternative is the Avila La Fonda Hotel, which is situated 9 miles (15 kilometers) away. Other possible hotel options are the Avila Lighthouse Suites and the San Luis Bay Inn.
Should you have the time, you could travel to other parts of the Central California region. Photograph the scenery of Central California's valleys and rolling hills. You could also wind your way through many of the area's lighthouses. In this corner of United States of America adventurous visitors might also try their hand at snowboarding, skiing and mountain biking.
14 miles (22 kilometers) away from Los Osos, you'll reach Pismo Beach, where you can spend the day visiting Pismo Beach Pier and Monarch Butterfly Grove. If you'd like to spend a few nights in Pismo Beach, check out the Sandcastle Inn and Pismo Lighthouse Suites. 9 miles (15 kilometers) to the southeast of Los Osos, is Avila Beach, which is home to the Avila Village Inn and Inn At Avila Beach. If you visit Avila Beach, keep a day to explore the Avila Beach Golf Resort and Central Coast Aquarium.
Get yourself a serving of local sport with a journey to Alex G. Spanos Stadium, which is 9 miles (15 kilometers) to the east of Los Osos. Wise travelers that want to book Travelocity-listed accommodation nearby can choose from the Madonna Inn or the Granada Hotel & Bistro.
San Luis Obispo County Regional Airport is located 11 miles (18 kilometers) outside Los Osos's town center. Modern visitors who desire to find accommodation in the area can find a night at the Courtyard by Marriott San Luis Obispo or Embassy Suites by Hilton San Luis Obispo.
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Oxford Suites Pismo Beach
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