Book Hotels in Los Osos, CA

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Los Osos hotels

Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

3 out of 5
1631 Monterey St San Luis Obispo CA
$167 nightly
The price is $190 total per night from Jun 10 to Jun 11
$190 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the ...
"Very nice"

Reviewed on Jun 3, 2026

Opens in a new windowQuality Suites Downtown San Luis Obispo
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

3.5 out of 5
2241 Price Street Pismo Beach CA
$259 nightly
The price is $297 total per night from Jun 8 to Jun 9
$297 total
Jun 8 - Jun 9
Total with taxes and fees
This Art Deco hotel features 3 hot tubs, an outdoor pool, and a restaurant. Families will appreciate the children's pool and barbecue grills. Enjoy the a rooftop ...
"Breakfasts were okay, parking was tight overall great time"

Reviewed on Jun 4, 2026

Opens in a new windowSeaCrest OceanFront Hotel
Madonna Inn

Madonna Inn

3.5 out of 5
100 Madonna Road San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $186 total per night from Jun 7 to Jun 8
$186 total
Jun 7 - Jun 8
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor tennis courts are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour ...
"Little gimmicky but overall acceptable. Clean room, plenty of towels, headboard on bed in pioneer room was detached and floppy but overall comfortable"

Reviewed on Jun 3, 2026

Opens in a new windowMadonna Inn
Oxford Suites Pismo Beach

Oxford Suites Pismo Beach

2.5 out of 5
651 Five Cities Dr Pismo Beach CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $159 total per night from Jun 7 to Jun 8
$159 total
Jun 7 - Jun 8
Total with taxes and fees
This motel features a gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
"Very close to the outlet and just a few mins drive from pismo beach. The cocktail hour was very good and the pool is nice and big"

Reviewed on Jun 3, 2026

Opens in a new windowOxford Suites Pismo Beach
Sandcastle Hotel on the Beach

Sandcastle Hotel on the Beach

3.5 out of 5
100 Stimson Ave Pismo Beach CA
Fully refundableReserve now, pay when you stay
$258 nightly
The price is $296 total per night from Jun 10 to Jun 11
$296 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features a restaurant, a rooftop terrace, and a bar/lounge. WiFi in public areas is free. Self parking, a coffee shop, and a terrace are also ...
"Very nice stay with ocean view."

Reviewed on Jun 3, 2026

Opens in a new windowSandcastle Hotel on the Beach
Apple Farm

Apple Farm

3.5 out of 5
2015 Monterey St San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $181 total per night from Jun 9 to Jun 10
$181 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Business travelers can take advantage of the free WiFi in public areas. Self parking, a garden, and a lobby ...
"We were very happy and would stay at this inn again, such a great value! The room was very spacious and no extra charges for water! The cookies were yummy, only wish we had a coffee maker in the room, however it is always available in the lobby."

Reviewed on Jun 3, 2026

Opens in a new windowApple Farm
Spyglass Inn

Spyglass Inn

3 out of 5
2705 Spyglass Dr Pismo Beach CA
Fully refundableReserve now, pay when you stay
$212 nightly
The price is $243 total per night from Jun 29 to Jun 30
$243 total
Jun 29 - Jun 30
Total with taxes and fees
This motel features an outdoor pool and a hot tub. WiFi in public areas is free. Self parking, a garden, and a lobby fireplace are also offered.
"Need bathroom by pool. Check in needs to be closer to 2pm not 4pm."

Reviewed on Jun 3, 2026

Opens in a new windowSpyglass Inn
Best Western Casa Grande Inn

Best Western Casa Grande Inn

2.5 out of 5
850 Oak Park Blvd Pismo Beach CA
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $141 total per night from Jun 8 to Jun 9
$141 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"This place was incredible for the price. The staff was friendly. The amenities were excellent. The hot tub was nice and hot. Even the lobby was very nice with a fireplace and free water, coffee, tea and hot chocolate. I think 24 hours. The only thing was, the breakfast could have been better. It ..."

Reviewed on Jun 3, 2026

Opens in a new windowBest Western Casa Grande Inn
Edgewater Inn And Suites

Edgewater Inn And Suites

2 out of 5
280 Wadsworth Ave Pismo Beach CA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $194 total per night from Jun 9 to Jun 10
$194 total
Jun 9 - Jun 10
Total with taxes and fees
This motel features an outdoor pool and a hot tub. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate freebies like ...
"This is absolutely my go to Hotel when visiting Pismo Beach. The proximity to downtown, beach access and awesome staff makes every stay AMAZING!"

Reviewed on Jun 4, 2026

Opens in a new windowEdgewater Inn And Suites
Don't see what you're looking for?
See all available properties in Los Osos
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Los Osos Hotel & Travel Guide\n

If you're not sure how to begin planning your San Luis Obispo trip, rest assured, because there's no end of perfect accommodation options in Los Osos. Thanks to our handy accommodation guide, you can explore 30 rooms within 6 miles (10 kilometers) of Los Osos's downtown region.

The Sea Pines is a great option for your stay because it is one of the most ideally located options, one of only a small number of choices that are within walking distance of the Los Osos central area.

The Dolphin Bay Resort And Spa is approximately 12 miles (19 kilometers) outside of the center of Los Osos. Another alternative is the Avila La Fonda Hotel, which is situated 9 miles (15 kilometers) away. Other possible hotel options are the Avila Lighthouse Suites and the San Luis Bay Inn.

Should you have the time, you could travel to other parts of the Central California region. Photograph the scenery of Central California's valleys and rolling hills. You could also wind your way through many of the area's lighthouses. In this corner of United States of America adventurous visitors might also try their hand at snowboarding, skiing and mountain biking.

14 miles (22 kilometers) away from Los Osos, you'll reach Pismo Beach, where you can spend the day visiting Pismo Beach Pier and Monarch Butterfly Grove. If you'd like to spend a few nights in Pismo Beach, check out the Sandcastle Inn and Pismo Lighthouse Suites. 9 miles (15 kilometers) to the southeast of Los Osos, is Avila Beach, which is home to the Avila Village Inn and Inn At Avila Beach. If you visit Avila Beach, keep a day to explore the Avila Beach Golf Resort and Central Coast Aquarium.

Get yourself a serving of local sport with a journey to Alex G. Spanos Stadium, which is 9 miles (15 kilometers) to the east of Los Osos. Wise travelers that want to book Travelocity-listed accommodation nearby can choose from the Madonna Inn or the Granada Hotel & Bistro.

San Luis Obispo County Regional Airport is located 11 miles (18 kilometers) outside Los Osos's town center. Modern visitors who desire to find accommodation in the area can find a night at the Courtyard by Marriott San Luis Obispo or Embassy Suites by Hilton San Luis Obispo.

Frequently asked questions

What are the top kid-friendly hotels in Los Osos?
From unique amenities to extra room, kid-friendly hotels are equipped with features that can help turn a nice family vacation into an extraordinary one. These Los Osos properties make vacationing with the youngsters a breeze: The whole team will enjoy their time at This house is a 3 bedroom(s), 2 bathrooms, located in Baywood-Los Osos, CA.. A king bed and a travel crib are among the things that help make this hotel a favorite. For a cabin experience by the sea. is another top place to stay. After a big day of exploring, return to your comfy room and amenities like a fireplace and pet-friendly facilities.
Where can I find cheap hotels in Los Osos?
At Travelocity you'll find really nice hotels in Los Osos at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Los Osos rather than in Los Osos. We may find you even better rates, too.
How do I find the best Los Osos hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Los Osos then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Los Osos?
The cheapest hotel in Los Osos is $141. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Los Osos?
There are 1,802 hotels in Los Osos on Travelocity.
What are the best hotels in Los Osos?
Los Osos has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Los Osos for you!
When is the best time to visit Los Osos?
If you want the joy of a fun-filled trip in peak season, visit Los Osos during March, June and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as August, October and December.
When is the cheapest time to stay in Los Osos?
Based on historic data is usually the cheapest month to visit Los Osos. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Los Osos?
There are multiple hotels in Los Osos that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Los Osos. We have plenty of kid-friendly hotels in Los Osos to choose from on Travelocity!
Why book a hotel in Los Osos through Travelocity?
Because we have the top hotels in Los Osos! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Los Osos on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Los Osos hotel reviews by fellow wanderers

SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Breakfasts were okay, parking was tight overall great time "
A verified traveler stayed at SeaCrest OceanFront Hotel
SeaCrest OceanFront Hotel

Explore More Ways to Travel with Travelocity