Book a hotel near Looe Key National Marine Sanctuary, United States of America
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Top hotels close to Looe Key National Marine Sanctuary
300’ Private Beach, Pool & Rooftop w Panoramic Ocean Views
Big Pine Key FL
6.66 mi from Looe Key National Marine Sanctuary
This vacation home features a garden, laundry facilities, and barbecue grills.
Barnacle Resort
1557 Long Beach Dr Big Pine Key FL
7.04 mi from Looe Key National Marine Sanctuary
$254 nightly
The price is $286 total per night
$286 total
Dec 15 - Dec 16
Total with taxes and fees
A rooftop terrace, free self parking, and barbecue grills are featured at this bed & breakfast. WiFi in public areas is free. Luggage storage is also provided.
Star Room Barnacle Resort
Big Pine Key FL
7.04 mi from Looe Key National Marine Sanctuary
$278 nightly
The price is $302 total per night
$302 total
Dec 15 - Dec 16
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Treehouse Private Village Barnacle Resort
Big Pine Key FL
7.04 mi from Looe Key National Marine Sanctuary
$538 nightly
The price is $586 total per night
$586 total
Dec 15 - Dec 16
Total with taxes and fees
This cabin includes a garden and barbecue grills.
Kitchen
Pet friendly
Ocean Depth Room Barnacle Resort
Big Pine Key FL
7.04 mi from Looe Key National Marine Sanctuary
$461 nightly
The price is $502 total per night
$502 total
Dec 15 - Dec 16
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Beach View Room Dormitory Room Barnacle Resort
Big Pine Key FL
7.04 mi from Looe Key National Marine Sanctuary
$411 nightly
The price is $447 total per night
$447 total
Dec 15 - Dec 16
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Ocean View Suite Barnacle Resort
Big Pine Key FL
7.04 mi from Looe Key National Marine Sanctuary
$461 nightly
The price is $499 total per night
$499 total
Dec 17 - Dec 18
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Anchors Aweigh: Stunning Oceanfront Views, Dockage, Private Pool, Tiki Hut, Spacious & Dog-Friendly!
Summerland Key FL
7.13 mi from Looe Key National Marine Sanctuary
This vacation home featured laundry facilities and barbecue grills.
Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool
Big Pine Key FL
7.16 mi from Looe Key National Marine Sanctuary
This vacation home features an outdoor pool and a hot tub. Families will appreciate the playground and onsite laundry facilities. Barbecue grills are provided for your convenience.
Sirena Key | Luxury Oceanfront Estate, Pool, Guest Cottage, Dock, 30min to Key West
Summerland Key FL
7.25 mi from Looe Key National Marine Sanctuary
A hot tub is featured at this vacation home, along with a garden and barbecue grills.
Gorgeous Beachfront Home with a pool. Water views from every direction.
Big Pine Key FL
7.35 mi from Looe Key National Marine Sanctuary
An outdoor pool is featured at this vacation home, along with laundry facilities and barbecue grills.
Looe Key Reef Resort
27340 Overseas Highway Summerland Key FL
Free Cancellation
Reserve now, pay when you stay
7.84 mi from Looe Key National Marine Sanctuary
$140 nightly
The price is $158 total per night
$158 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A picnic area, express check-in, and luggage storage are also on offer.
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See all available properties in Looe Key National Marine Sanctuary
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Looe Key National Marine Sanctuary hotels essential information
Accommodation | 787 hotels |
|---|---|
Lowest Price | $158 |
Highest Price | $586 |
Popular hotels | Looe Key Reef Resort, 300’ Private Beach, Pool & Rooftop w Panoramic Ocean Views, Barnacle Resort, Star Room Barnacle Resort, Treehouse Private Village Barnacle Resort, Ocean Depth Room Barnacle Resort, Beach View Room Dormitory Room Barnacle Resort, Ocean View Suite Barnacle Resort, Anchors Aweigh: Stunning Oceanfront Views, Dockage, Private Pool, Tiki Hut, Spacious & Dog-Friendly!, Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool, Sirena Key | Luxury Oceanfront Estate, Pool, Guest Cottage, Dock, 30min to Key West, Gorgeous Beachfront Home with a pool. Water views from every direction. |
Recent Looe Key National Marine Sanctuary hotel reviews by fellow wanderers
Looe Key Reef Resort
5 out of 5
Posted 7 days ago
Travelocity Verified Review
"Was nice roo.s and close to my charter boat captain "
A verified traveler stayed at Looe Key Reef Resort
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