Book a hotel near Looe Key National Marine Sanctuary, United States of America
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Top hotels close to Looe Key National Marine Sanctuary

Ocean Front Beach Home on Semi Private Island Only Accessible by Boat
5.98 mi from Looe Key National Marine Sanctuary
Stay at this vacation home in Big Pine Key. Enjoy a beach locale and air conditioning. Popular attractions Cook Island and Hopkins Island are located nearby.
Pet friendly
Air conditioning

300’ Private Beach, Pool & Rooftop w Panoramic Ocean Views
6.66 mi from Looe Key National Marine Sanctuary
This vacation home features a garden, laundry facilities, and barbecue grills.
Pool
Kitchen

Barnacle Resort
1557 Long Beach Dr, Big Pine Key, FL
7.04 mi from Looe Key National Marine Sanctuary
$251 nightly
The price is $283 total per night
$283 total
Oct 21 - Oct 22
Total with taxes and fees
A rooftop terrace, free self parking, and barbecue grills are featured at this bed & breakfast. WiFi in public areas is free. Luggage storage is also provided.
Parking included
Free WiFi

Treehouse Private Village Barnacle Resort
7.04 mi from Looe Key National Marine Sanctuary
$545 nightly
The price is $593 total per night
$593 total
Oct 16 - Oct 17
Total with taxes and fees
This cabin includes a garden and barbecue grills.
Kitchen
Pet friendly

Star Room Barnacle Resort
7.04 mi from Looe Key National Marine Sanctuary
$279 nightly
The price is $303 total per night
$303 total
Oct 21 - Oct 22
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Pet friendly
Air conditioning

Beach View Room Dormitory Room Barnacle Resort
7.04 mi from Looe Key National Marine Sanctuary
$411 nightly
The price is $447 total per night
$447 total
Oct 16 - Oct 17
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Pet friendly
Air conditioning

Ocean Depth Room Barnacle Resort
7.04 mi from Looe Key National Marine Sanctuary
$468 nightly
The price is $509 total per night
$509 total
Oct 21 - Oct 22
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Pet friendly
Air conditioning

Ocean View Suite Barnacle Resort
7.04 mi from Looe Key National Marine Sanctuary
$468 nightly
The price is $506 total per night
$506 total
Oct 16 - Oct 17
Total with taxes and fees
This apartment includes a garden and barbecue grills.
Pet friendly
Air conditioning

Anchors Aweigh 10% off Fall 2025!
7.13 mi from Looe Key National Marine Sanctuary
This vacation home featured laundry facilities and barbecue grills.
Pool
Kitchen

Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool
7.16 mi from Looe Key National Marine Sanctuary
This vacation home features an outdoor pool and a hot tub. Families will appreciate the playground and onsite laundry facilities. Barbecue grills are provided for your convenience.
Pool
Hot Tub

Lookout On Long Beach: Discover Serenity at Your Private Waterfront Sanctuary, Amazing Sunset Views!
7.23 mi from Looe Key National Marine Sanctuary
This vacation home featured laundry facilities and barbecue grills.
Kitchen
Washer

Looe Key Reef Resort
27340 Overseas Highway, Summerland Key, FL
Free Cancellation
Reserve now, pay when you stay
7.84 mi from Looe Key National Marine Sanctuary
$175 nightly
The price is $197 total per night
$197 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A picnic area, express check-in, and luggage storage are also on offer.
Pool
Pet friendly
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See all available properties in Looe Key National Marine Sanctuary
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Looe Key National Marine Sanctuary hotels essential information
Accommodation | 786 hotels |
---|---|
Lowest Price | $197 |
Highest Price | $593 |
Popular hotels | Ocean Front Beach Home on Semi Private Island Only Accessible by Boat, 300’ Private Beach, Pool & Rooftop w Panoramic Ocean Views, Barnacle Resort, Treehouse Private Village Barnacle Resort, Star Room Barnacle Resort, Beach View Room Dormitory Room Barnacle Resort, Ocean Depth Room Barnacle Resort, Looe Key Reef Resort, Ocean View Suite Barnacle Resort, Anchors Aweigh 10% off Fall 2025!, Keys To The Kingdom! Private Oceanfront Retreat with Beach and Pool, Lookout On Long Beach: Discover Serenity at Your Private Waterfront Sanctuary, Amazing Sunset Views! |
Recent Looe Key National Marine Sanctuary hotel reviews by fellow wanderers

Star Room Barnacle Resort
5 out of 5
Posted 1 month ago
Travelocity Verified Review
"We loved the location - quiet and secluded - away from everything but not so far away that you felt isolated. All very clean and amenities were as described."
A verified traveler stayed at Star Room Barnacle Resort
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