Book Hotels in Central San Diego, CA

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Top Central San Diego hotels

Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $263 total per night from Jan 8 to Jan 9
$263 total
Jan 8 - Jan 9
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Amazing property.

Reviewed on Jan 6, 2026

Opens in a new windowLafayette Hotel & Club
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
$179 nightly
The price is $206 total per night from Jan 11 to Jan 12
$206 total
Jan 11 - Jan 12
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Full dining room service was amazing and rooms were always kept clean

Reviewed on Jan 4, 2026

Opens in a new windowLegacy Resort Hotel & Spa
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $112 total per night from Jan 27 to Jan 28
$112 total
Jan 27 - Jan 28
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Great location close to the 8 freeway. Tip : ask for a room opposite the freeway. The amenities are good and the staff was very nice.

Reviewed on Jan 6, 2026

Opens in a new windowHampton Inn San Diego/Mission Valley
San Diego Marriott La Jolla

San Diego Marriott La Jolla

4 out of 5
4240 La Jolla Village Dr La Jolla CA
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Jan 10 to Jan 11
$178 total
Jan 10 - Jan 11
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Best hotel staff and stay

Reviewed on Jan 4, 2026

Opens in a new windowSan Diego Marriott La Jolla
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $138 total per night from Jan 25 to Jan 26
$138 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
The staff was kind and courteous , the rooms were clean, well and supplied with necessities. We received free cookies upon entry, the gym, indoor pool and jacuzzi were amazing. The only surprise that was quite significant and is not mentioned in the Expedia or hotel site description is that doubletree ...

Reviewed on Jan 5, 2026

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $141 total per night from Jan 18 to Jan 19
$141 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The room was nice, clean, and quiet.

Reviewed on Jan 6, 2026

Opens in a new windowHilton San Diego Mission Valley
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $81 total per night from Jan 14 to Jan 15
$81 total
Jan 14 - Jan 15
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
Room was good and staff was very friendly and helpful.

Reviewed on Jan 2, 2026

Opens in a new windowBest Western Seven Seas
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jan 15 to Jan 16
$97 total
Jan 15 - Jan 16
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
The room was very clean and comfortable and the staff were friendly and helpful. A great value!

Reviewed on Dec 26, 2025

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Jan 15 to Jan 16
$92 total
Jan 15 - Jan 16
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. ...
The staff, Breanna and Josh were super nice and helpful. My room was comfortable. I didn't get a chance to see the rest of the property.

Reviewed on Jan 3, 2026

Opens in a new windowCalifornia Suites Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Central San Diego hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central San Diego Hotel & Travel Guide\n

You can discover a wide variety of apartment and hotel options to choose from in Central San Diego. Travelocity's booking page currently is where you will find 51 hotel establishments within a 6-mile (10-kilometer) distance of downtown Central San Diego.

You'll find Residence Inn By Marriott San Diego Central and Hampton Inn San Diego-Kearny Mesa within wandering distance of Central San Diego's city center.

Students, families and those watching their dollars will find some great Central San Diego accommodation options that won't blow holes in the wallet. The Extended Stay America San Diego - Mission Valley - Stadium and the Quality Inn San Diego Miramar are amongst the other cheaper hotels worth investigating.

The Rancho Valencia Resort and Spa is located 10 miles (16 kilometers) away from central Central San Diego. Another place to stay is the Fairmont Grand Del Mar, which is 7 miles (11 kilometers) away. The Hotel del Coronado along with the Pantai Inn are alternate bases around Central San Diego.

If time is on your side, why not broaden your horizons and get to know the many other attractions around Southern California during your stay in the area? Southern California offers beaches, mountains and rolling hills, and interesting tourist places of interest are art galleries, open-air exhibits and street art. Modern visitors in this part of United States of America commonly enjoy snowboarding.

Looking for more activities? Consider spending a few hours enjoying Centennial Park and Coronado Ferry Landing, which you'll find in Coronado, 13 miles (21 kilometers) south of Central San Diego. The Marriott Coronado Island Resort & Spa and Hard Rock Hotel San Diego are just some examples of the apartment and hotel choices in Coronado. Or stay in Carlsbad, 20 miles (34 kilometers) to the northwest of Central San Diego, where you can choose between the Four Seasons Residence Club Aviara, North San Diego and Park Hyatt Aviara Resort, Spa & Golf Club. Whether you're just passing through or staying in Carlsbad, set aside some time to visit the Carlsbad Premium Outlets and Carlsbad State Beach.

San Diego International Airport is a practical gateway for air travel, and can be found 9 miles (15 kilometers) away from downtown Central San Diego. Conveniently located Travelocity-listed hotels include Paradise Point Resort & Spa and San Diego Marriott Gaslamp Quarter.

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