Book Hotels in Central San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Central San Diego hotels

Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $259 total per night from Dec 9 to Dec 10
$259 total
Dec 9 - Dec 10
Total with taxes and fees
This smoke-free hotel features 2 restaurants, 3 bars/lounges, and a poolside bar. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
Very hip place to stay with lobby bars always hopping. Rooms were cute and nice neighborhood.

Reviewed on Dec 1, 2025

Opens in a new windowLafayette Hotel & Club
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Dec 7 to Dec 8
$175 total
Dec 7 - Dec 8
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
The room was very clean.

Reviewed on Dec 1, 2025

Opens in a new windowLegacy Resort Hotel & Spa
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $90 total per night from Dec 15 to Dec 16
$90 total
Dec 15 - Dec 16
Total with taxes and fees
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...
Check in process is always effortless as staff is well trained. This retro vintage property is in amazing shape, which is no easy feat. This is my third time to stay here and it is a favorite for us as the property just has so much character, and having the world famous Waffle Spot on property for ...

Reviewed on Dec 3, 2025

Opens in a new windowKings Inn San Diego
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Jan 4 to Jan 5
$112 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Spacious and clean rooms, helpful staff

Reviewed on Dec 2, 2025

Opens in a new windowHampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Dec 11 to Dec 12
$136 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Staff was great, room was clean every day. Counter staff service was excellent.

Reviewed on Nov 30, 2025

Opens in a new windowSheraton Mission Valley San Diego Hotel
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Dec 14 to Dec 15
$126 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 20 conference rooms, free WiFi in public areas, ...
Great hotel in a great area - would definitely stay here again.

Reviewed on Dec 2, 2025

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $101 total per night from Dec 23 to Dec 24
$101 total
Dec 23 - Dec 24
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Staff is kind. I left my trip very early due to a health reason. I was supposed to stay until 12/1/25 but I left 11/30/25 at 130am. I never got a parking invoice although I called to get one. There was some misinformation from one employee to the next. I hope I’m not charged for anything I didn’t ...

Reviewed on Dec 2, 2025

Opens in a new windowHandlery Hotel
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Dec 11 to Dec 12
$136 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The room was perfect. Would like some lemon water in the lobby and free breakfast, but overall, very nice.

Reviewed on Dec 1, 2025

Opens in a new windowHilton San Diego Mission Valley
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

4 out of 5
1515 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Dec 11 to Dec 12
$136 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Staff

Reviewed on Dec 3, 2025

Opens in a new windowDoubleTree by Hilton San Diego - Hotel Circle
Don't see what you're looking for?
See all available properties in Central San Diego
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Central San Diego hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central San Diego Hotel & Travel Guide\n

You can discover a wide variety of apartment and hotel options to choose from in Central San Diego. Travelocity's booking page currently is where you will find 51 hotel establishments within a 6-mile (10-kilometer) distance of downtown Central San Diego.

You'll find Residence Inn By Marriott San Diego Central and Hampton Inn San Diego-Kearny Mesa within wandering distance of Central San Diego's city center.

Students, families and those watching their dollars will find some great Central San Diego accommodation options that won't blow holes in the wallet. The Extended Stay America San Diego - Mission Valley - Stadium and the Quality Inn San Diego Miramar are amongst the other cheaper hotels worth investigating.

The Rancho Valencia Resort and Spa is located 10 miles (16 kilometers) away from central Central San Diego. Another place to stay is the Fairmont Grand Del Mar, which is 7 miles (11 kilometers) away. The Hotel del Coronado along with the Pantai Inn are alternate bases around Central San Diego.

If time is on your side, why not broaden your horizons and get to know the many other attractions around Southern California during your stay in the area? Southern California offers beaches, mountains and rolling hills, and interesting tourist places of interest are art galleries, open-air exhibits and street art. Modern visitors in this part of United States of America commonly enjoy snowboarding.

Looking for more activities? Consider spending a few hours enjoying Centennial Park and Coronado Ferry Landing, which you'll find in Coronado, 13 miles (21 kilometers) south of Central San Diego. The Marriott Coronado Island Resort & Spa and Hard Rock Hotel San Diego are just some examples of the apartment and hotel choices in Coronado. Or stay in Carlsbad, 20 miles (34 kilometers) to the northwest of Central San Diego, where you can choose between the Four Seasons Residence Club Aviara, North San Diego and Park Hyatt Aviara Resort, Spa & Golf Club. Whether you're just passing through or staying in Carlsbad, set aside some time to visit the Carlsbad Premium Outlets and Carlsbad State Beach.

San Diego International Airport is a practical gateway for air travel, and can be found 9 miles (15 kilometers) away from downtown Central San Diego. Conveniently located Travelocity-listed hotels include Paradise Point Resort & Spa and San Diego Marriott Gaslamp Quarter.

Recent Central San Diego hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity