Find and compare 3 Star hotels in Serra Mesa

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Top Serra Mesa 3 Star hotels

Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Mar 29 to Mar 30
$87 total
Mar 29 - Mar 30
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
7.8/10 Good! (3,299 reviews)
The receptionist was very helpful

Reviewed on Mar 16, 2026

Opens in a new windowBest Western Seven Seas
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $126 total per night from Apr 5 to Apr 6
$126 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
8.2/10 Very Good! (2,341 reviews)
Nice hotel

Reviewed on Mar 16, 2026

Opens in a new windowHandlery Hotel
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 out of 5
1055 1st Ave San Diego CA
Fully refundableReserve now, pay when you stay
$141 nightly
The price is $164 total per night from Apr 3 to Apr 4
$164 total
Apr 3 - Apr 4
Total with taxes and fees
A gym is featured at this hotel, along with valet parking. WiFi in public areas is free. A business center, a snack bar/deli, and a grocery/convenience store ...
8.6/10 Excellent! (1,528 reviews)
The staff was so sweet, valet was nice and easy, the room was clean, bed was comfortable, the view was so cute! And the hotel is within walking distance of so many things.

Reviewed on Mar 16, 2026

Opens in a new windowThe Bristol Hotel San Diego
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Mar 23 to Mar 24
$123 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
8/10 Very Good! (2,556 reviews)
This hotel fits our need for a clean, comfortable and convenient stop when we are in San Diego. The staff is accommodating and our room was pleasant and roomy. We have stayed here previously and this was by far our best experience with a large accessible room. We unloaded the car directly into our ...

Reviewed on Mar 17, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,204 reviews)
Expensive parking!

Reviewed on Mar 16, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $139 total per night from Apr 7 to Apr 8
$139 total
Apr 7 - Apr 8
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
8.6/10 Excellent! (1,822 reviews)
Appreciated the fitness room! Very close to convention center, super friendly staff.

Reviewed on Mar 17, 2026

Opens in a new windowThe Sofia Hotel
La Jolla Shores Hotel

La Jolla Shores Hotel

3 out of 5
8110 Camino Del Oro La Jolla CA
$245 nightly
The price is $281 total per night from Apr 6 to Apr 7
$281 total
Apr 6 - Apr 7
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a hot tub are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (1,375 reviews)
Renovations will make it better

Reviewed on Mar 15, 2026

Opens in a new windowLa Jolla Shores Hotel
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $217 total per night from Apr 5 to Apr 6
$217 total
Apr 5 - Apr 6
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
9/10 Wonderful! (4,166 reviews)
Great location and friendly staff

Reviewed on Mar 16, 2026

Opens in a new windowThe Dana on Mission Bay
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
$192 nightly
The price is $221 total per night from Mar 30 to Mar 31
$221 total
Mar 30 - Mar 31
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
9.2/10 Wonderful! (3,485 reviews)
Excellent staff. Excellent location with a view of the marina and gorgeous sunset over Point Loma. We enjoyed the balcony and the friendly seagulls visiting us were so cute. It was a nice peaceful getaway. Hidden gem. We will return!!

Reviewed on Mar 17, 2026

Opens in a new windowBay Club Hotel & Marina
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

3 out of 5
2051 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $174 total per night from Apr 5 to Apr 6
$174 total
Apr 5 - Apr 6
Total with taxes and fees
A marina, 2 outdoor pools, and 2 outdoor tennis courts are all featured at this smoke-free hotel. Enjoy the 2 hot tubs and perks like free WiFi. A gym, a restaurant, ...
8.8/10 Excellent! (1,597 reviews)
Clean room great views

Reviewed on Mar 17, 2026

Opens in a new windowBest Western Plus Island Palms Hotel & Marina
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