Find and compare 3 Star hotels in Serra Mesa

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Top Serra Mesa 3 Star hotels

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $209 total per night from Jun 7 to Jun 8
$209 total
Jun 7 - Jun 8
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
8.6/10 Excellent! (2,036 reviews)
The bus from the airport to the hotel was great, 18 minutes and it drops you off right in front of the hotel. Staff was nice and always present.

Reviewed on May 15, 2026

Opens in a new windowThe Sofia Hotel
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $94 total per night from May 19 to May 20
$94 total
May 19 - May 20
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
7.8/10 Good! (3,491 reviews)
Gg

Reviewed on May 15, 2026

Opens in a new windowBest Western Seven Seas
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundable
$119 nightly
The price is $138 total per night from May 25 to May 26
$138 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
8.8/10 Excellent! (1,568 reviews)
Staff was the best! Without the staff service a business is nothing. Everything else in the room was nice clean bed, clean restrooms, complete amenities that I needed which is not a lot. The price is a bit high however it is a clean nice hotel. I would come back.

Reviewed on May 15, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from May 18 to May 19
$97 total
May 18 - May 19
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
8/10 Very Good! (2,692 reviews)
Staff was great. Had to switch rooms because the first one reeked of pee. Second one smelt old but better than pee. The outside area also smells of pee

Reviewed on May 13, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor

3.5 out of 5
San Diego CA
Fully refundable
$108 nightly
The price is $122 total per night from May 25 to May 26
$122 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool and a rooftop terrace. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free full breakfast ...
7.8/10 Good! (1,505 reviews)
Parking is terrible at this location. Our room was facing the street and you can hear the cars zooming by all night. We did not get a full night rest with the constant noise. Also the outside of the hotel lacked cleanliness.

Reviewed on May 15, 2026

Opens in a new windowComfort Inn San Diego Airport At The Harbor
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $148 total per night from May 25 to May 26
$148 total
May 25 - May 26
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
8.4/10 Very Good! (2,528 reviews)
Very nice and clean. The only thing, and this is small, the closet door was off the track and the refrigerator wasnt very cool.but in the positive, we got clean towels every day!

Reviewed on May 14, 2026

Opens in a new windowHandlery Hotel
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from May 18 to May 19
$175 total
May 18 - May 19
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free ...
9.2/10 Wonderful! (3,573 reviews)
We've stayed here before and love it.

Reviewed on May 15, 2026

Opens in a new windowBay Club Hotel & Marina
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $257 total per night from May 17 to May 18
$257 total
May 17 - May 18
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
9/10 Wonderful! (4,347 reviews)
Firefly dinner was great! Loved the lobster mac & cheese and calamari! Salmon and coconut rice was very tasteful! I loved the hospitality and everyone there was very friendly! I loved this resort!

Reviewed on May 14, 2026

Opens in a new windowThe Dana on Mission Bay
La Jolla Shores Hotel

La Jolla Shores Hotel

3 out of 5
8110 Camino Del Oro La Jolla CA
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $320 total per night from May 31 to Jun 1
$320 total
May 31 - Jun 1
Total with taxes and fees
2 outdoor tennis courts, an outdoor pool, and a hot tub are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
8.8/10 Excellent! (1,357 reviews)
The location and restaurant are top notch. The staff was mixed from ok to good. The local shuttle was limited in terms of operation compared to the past.

Reviewed on May 15, 2026

Opens in a new windowLa Jolla Shores Hotel
Inn By The Sea La Jolla

Inn By The Sea La Jolla

3.5 out of 5
7830 Fay Ave La Jolla CA
Fully refundableReserve now, pay when you stay
$217 nightly
The price is $249 total per night from May 17 to May 18
$249 total
May 17 - May 18
Total with taxes and fees
An outdoor pool, self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Express check-out, dry cleaning, and luggage ...
9.4/10 Exceptional! (1,798 reviews)
Property was being remodeled, so it was a little sketchy. Parking was hit or miss and we were charged $20 per night. Over all we loved the location and the staff were great..

Reviewed on May 12, 2026

Opens in a new windowInn By The Sea La Jolla
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