Explore top 2025 4 Star Hotels in San Mateo

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Top San Mateo 4 Star hotels

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $281 total per night from Oct 31 to Nov 1
$281 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
9.2/10 Wonderful! (1,961 reviews)
"Kind and efficient check in process. Breakfast buffet had great options. Enjoyed the room and the view. Convenient to public transport as well."

Reviewed on Oct 18, 2025

Opens in a new windowHyatt Regency San Francisco
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Oct 30 to Oct 31
$140 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self ...
8.6/10 Excellent! (1,898 reviews)
"Great stay."

Reviewed on Oct 17, 2025

Opens in a new windowHilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $196 total per night from Oct 30 to Oct 31
$196 total
Oct 30 - Oct 31
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.8/10 Excellent! (7,027 reviews)
"I can't speak to whether it's healthy or not, but plentiful and plenty of options and it was nice to have an included breakfast. Not typical in US hotels"

Reviewed on Oct 18, 2025

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4 out of 5
555 N Point St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$170 nightly
The price is $200 total per night from Nov 2 to Nov 3
$200 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,445 reviews)
"Great room"

Reviewed on Oct 16, 2025

Opens in a new windowHyatt Centric Fisherman's Wharf San Francisco
Oakland Marriott City Center

Oakland Marriott City Center

4 out of 5
1001 Broadway, Oakland, CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Oct 26 to Oct 27
$148 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,010 reviews)
"Great location to access Bart"

Reviewed on Oct 18, 2025

Opens in a new windowOakland Marriott City Center
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $149 total per night from Nov 2 to Nov 3
$149 total
Nov 2 - Nov 3
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
8.8/10 Excellent! (2,671 reviews)
"Nice & clean will be back."

Reviewed on Oct 18, 2025

Opens in a new windowClub Quarters Hotel in San Francisco
Hyatt Regency San Francisco Downtown SOMA

Hyatt Regency San Francisco Downtown SOMA

4 out of 5
50 3rd St, San Francisco, CA
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $225 total per night from Oct 31 to Nov 1
$225 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
9.2/10 Wonderful! (1,306 reviews)
"I will definitely make a return visit here."

Reviewed on Oct 17, 2025

Opens in a new windowHyatt Regency San Francisco Downtown SOMA
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4 out of 5
999 California Street, San Francisco, CA
Fully refundable
$218 nightly
The price is $257 total per night from Oct 31 to Nov 1
$257 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
9/10 Wonderful! (1,158 reviews)
"We enjoyed our stay. The rooms are decorated nicely and are clean. The staff is friendly and helpful. We went to the Top of the Mark for coctails and appetizers (they don’t serve dinner). The view was amazing and well worth the visit. Overall very pleased with our stay."

Reviewed on Oct 16, 2025

Opens in a new windowInterContinental Mark Hopkins by IHG
Hyatt Regency Santa Clara

Hyatt Regency Santa Clara

4 out of 5
5101 Great America Pkwy, Santa Clara, CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $164 total per night from Oct 25 to Oct 26
$164 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9/10 Wonderful! (1,018 reviews)
"Nice hotel overall"

Reviewed on Oct 18, 2025

Opens in a new windowHyatt Regency Santa Clara
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd, San Francisco, CA
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $334 total per night from Nov 1 to Nov 2
$334 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and valet ...
9.6/10 Exceptional! (1,435 reviews)
"Great all round experience"

Reviewed on Oct 16, 2025

Opens in a new windowGrand Hyatt at SFO
Don't see what you're looking for?
See all available properties in San Mateo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels San Mateo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Mateo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Mateo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Mateo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Mateo hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity