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Top hotels in Mira Mesa

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$248 nightly
The price is $287 total per night from Apr 6 to Apr 7
$287 total
Apr 6 - Apr 7
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
Super close to the stadium prime location if going to a padres game

Reviewed on Apr 5, 2026

Opens in a new windowHard Rock Hotel San Diego
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
$246 nightly
The price is $285 total per night from Apr 6 to Apr 7
$285 total
Apr 6 - Apr 7
Total with taxes and fees
This hotel features 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great overall experience. The staff we’re helpful and polite. The room was nice and the views are amazing. The hotel has many great food options, you don’t have to go far to enjoy your visit.

Reviewed on Apr 4, 2026

Opens in a new windowManchester Grand Hyatt San Diego
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $234 total per night from Apr 12 to Apr 13
$234 total
Apr 12 - Apr 13
Total with taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. If you want to take your pet along, this pet-friendly property offers everything ...
I Love this property! My family has stayed here three years in a row, and it's first class every time. The room, the staff, and the restaurant are incredible!

Reviewed on Apr 4, 2026

Opens in a new windowThe Dana on Mission Bay
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $229 total per night from Apr 12 to Apr 13
$229 total
Apr 12 - Apr 13
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Staff was very nice. Open 24/7 for any questions and concerns. Room had good space (we had a Lanai room) so some chairs in the front to sit.

Reviewed on Apr 4, 2026

Opens in a new windowParadise Point Resort & Spa
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundable
$135 nightly
The price is $157 total per night from Apr 23 to Apr 24
$157 total
Apr 23 - Apr 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Front desk was okay. There was no microwaves in the whole place and one gentleman did amazing but the other simply didn’t want to warm up the meals for me in his break room.

Reviewed on Apr 5, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $148 total per night from Apr 13 to Apr 14
$148 total
Apr 13 - Apr 14
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
The pool is great! And a nice large hot tub

Reviewed on Apr 4, 2026

Opens in a new windowHandlery Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $211 total per night from Apr 7 to Apr 8
$211 total
Apr 7 - Apr 8
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center and free WiFi in public ...
It has a great location, walking distance into Little Italy and the USS Midway museum. It is within a 10 min drive from Old Town, Gaslamp, and the Zoo. It was a great stay, comfortable, convenient, clean, and accommodating.

Reviewed on Apr 5, 2026

Opens in a new windowWyndham San Diego Bayside
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $94 total per night from Apr 14 to Apr 15
$94 total
Apr 14 - Apr 15
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
Dated room. Silverfish in the bathroom. The floor was hot so I notified the front desk that they probably have a broken hot water pipe. I had it happen in my house when I lived in San Diego. Silverfish eat mold, which I am allergic to. I won’t be staying there again.

Reviewed on Apr 4, 2026

Opens in a new windowBest Western Seven Seas
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $121 total per night from Apr 13 to Apr 14
$121 total
Apr 13 - Apr 14
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
They had a pool but we didn’t go swimming this trip. The hotel was run down. The staff was awesome. The cleaning ladies were very sweet. The bed were very comfortable. They need to replace the carpet in the rooms.

Reviewed on Apr 5, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mira Mesa Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Mira Mesa area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Mira Mesa to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Mira Mesa are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Mira Mesa hotel reviews by fellow wanderers

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Super close to the stadium prime location if going to a padres game"
A verified traveler stayed at Hard Rock Hotel San Diego
Hard Rock Hotel San Diego

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