Find a Hotel in Little Italy

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels in Little Italy

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $274 total per night from Apr 5 to Apr 6
$274 total
Apr 5 - Apr 6
Total with taxes and fees
A nightclub, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free ...
Hard Rock was very nice, clean and staff was nice. It is catered to mostly adults so I would probably not recommend to stay here with kids next time but a nice hotel nonetheless.

Reviewed on Mar 11, 2026

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Lovely newly updated rooms, wonderful staff, superb value- thank you for an excellent stay!

Reviewed on Mar 11, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Urban Boutique Hotel

Urban Boutique Hotel

3 out of 5
1654 Columbia Street San Diego CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $183 total per night from Apr 6 to Apr 7
$183 total
Apr 6 - Apr 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
If you are looking for an affordable place to stay in little italy, this is right in the middle of everything. however the hotel is just a little run down and the walls were so thin that we couldn’t get any sleep due to our neighbors TV blasting. Also check-in was at 3 pm but our room wasn’t ready ...

Reviewed on Mar 10, 2026

Opens in a new windowUrban Boutique Hotel
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Fully refundableReserve now, pay when you stay
$172 nightly
The price is $200 total per night from Apr 7 to Apr 8
$200 total
Apr 7 - Apr 8
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Great front desk.

Reviewed on Mar 10, 2026

Opens in a new windowThe Sofia Hotel
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Apr 1 to Apr 2
$136 total
Apr 1 - Apr 2
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Incredibly nice pool and hot tub, feels like you’re at a resort. Breakfast at the restaurant was delicious and reasonable. Easy access in and out of hotel. Room was clean and nice, and the price was fabulous. I enjoy boutique hotels over chain hotels and this one didn’t disappoint.

Reviewed on Mar 11, 2026

Opens in a new windowHandlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $113 total per night from Apr 12 to Apr 13
$113 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
did not look

Reviewed on Mar 11, 2026

Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Mar 29 to Mar 30
$84 total
Mar 29 - Mar 30
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
Need to update bedding.

Reviewed on Mar 12, 2026

Opens in a new windowBest Western Seven Seas
Hotel Zindel

Hotel Zindel

2 out of 5
505 W Grape St San Diego CA
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $109 total per night from Mar 16 to Mar 17
$109 total
Mar 16 - Mar 17
Total with taxes and fees
This hotel features a virtual front desk.
No actual on sight staff available AND you have to share bathrooms with other visitors. They also do not do refunds.

Reviewed on Mar 9, 2026

Opens in a new windowHotel Zindel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $281 total per night from Apr 5 to Apr 6
$281 total
Apr 5 - Apr 6
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 2 restaurants. Family-friendly amenities include mini golf and kid-friendly dining, along with ...
Opens in a new windowParadise Point Resort & Spa
Don't see what you're looking for?
See all available properties in Little Italy
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Little Italy Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Little Italy area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Little Italy to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Little Italy are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Little Italy hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity