Explore top 2026 5 Star Hotels in Duck Key
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Top Duck Key 5 Star hotels

Isla Bella Beach Resort & Spa
"We had a wonderful stay! The hotel was clean, comfortable, and perfectly located right on the beach. The staff was friendly and helpful throughout our visit, and the amenities made our stay even more enjoyable. Waking up to beautiful ocean views and having easy beach access was the highlight of our ..."
Reviewed on Jun 8, 2026
Five Star Hotels in Duck Key
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Duck Key to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Duck Key 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Duck Key before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Duck Key hotel reviews by fellow wanderers

La Siesta Resort & Villas
"This was a big disappointment. Apt for 8 with no kitchen, stove or oven where are you supposed to cook if you go with kids / teenagers? No restaurant in the property, no convenience store , no vending machines. We had to drive to get some milk or even water. No guest wants to have to make the day more difficult when it’s time to eat right? Staff is not really helpful sitting the FD like they’re on break they don’t seem to be worried about guests too much … beach access is non existent … next to the pier you can get in the water but if you want to have some keys beach access you’ll need to drive to three waters resort… THATS A BEACH . We found ants all over the copy tee so so t even think about leaving anything open you’ll have an infestation 10 min later …. At night there’s no bar, no music, no action, activity or NADA. Totally quiet and almost dark, it would be a good suggestion to have something to gather ppl , sell some drinks and they would probably make a lot of money . No breakfast included they give you free coffee and they sell some boxes wth sausages eggs and croissants for around $15 which is pretty much the price of a regular breakfast anywhere , but they give it in a box so you take it to go…. Terrible idea ! Definitely not what we expected . We love the keys but if you’re looking for relaxation and some entertainment this is not the place . Super overvalued ."
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