Explore top 2025 5 Star Hotels in Clayton

Name: The Ritz-Carlton, St. Louis
Price range: $733 total
Rating: 9.2

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Top Clayton 5 Star hotels

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO

Fully refundable

$425 nightly

$497 total

Oct 25 - Oct 26

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,002 reviews)

"Great help and classy property"

Reviewed on Sep 22, 2025

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO

Fully refundableReserve now, pay when you stay

$629 nightly

$733 total

Oct 2 - Oct 3

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (550 reviews)

"Service is exceptional!!!"

Reviewed on Sep 2, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.