Explore top 2026 5 Star Hotels in Clayton

Name: The Ritz-Carlton, St. Louis
Price range: $583 total
Rating: 9.2

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Top Clayton 5 Star hotels

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

Fully refundableReserve now, pay when you stay

$415 nightly

$485 total

Jan 20 - Jan 21

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,000 reviews)

Amazing

Reviewed on Jan 10, 2026

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

Fully refundableReserve now, pay when you stay

$499 nightly

$583 total

Jan 25 - Jan 26

Total with taxes and fees

This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (556 reviews)

Very courteo

Reviewed on Jan 13, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.