Explore top 2026 4 Star Hotels in Duck Key

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Top Duck Key 4 Star hotels

Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $318 total per night from Apr 21 to Apr 22
$318 total
Apr 21 - Apr 22
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,276 reviews)
Great location. Eat at Lazy Days next door and Flagler Station if you want more upscale. They have a water taxi that unfortunately we didn’t get to go on because it was so windy but hope to go again and get on it next time.

Reviewed on Apr 12, 2026

Opens in a new windowAmara Cay Resort
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$377 nightly
The price is $423 total per night from Apr 26 to Apr 27
$423 total
Apr 26 - Apr 27
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8/10 Very Good! (1,019 reviews)
The staff members were responsive and helpful, but unfortunately the overall experience at the village was very disappointing—especially for a stay of just two nights. The room had a strong humid smell, the sofa was worn out and dirty, and the kitchen was poorly equipped and not well supplied. The ...

Reviewed on Apr 13, 2026

Opens in a new windowHawks Cay Resort
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

4 out of 5
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $313 total per night from May 3 to May 4
$313 total
May 3 - May 4
Total with taxes and fees
This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...
8.8/10 Excellent! (1,185 reviews)
For a two night stay, 3 rooms. Totaling over $4,000, what do you think? Worms in room, cockroaches at entrance, toilet paper so thin you might as well use bare fingers, towels that can rub your skin off, service at coffee stand that took forever, noise from across the hall all night. $50 to park ...

Reviewed on Apr 12, 2026

Opens in a new windowFaro Blanco Resort Marathon Florida Keys, Curio by Hilton
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$271 nightly
The price is $305 total per night from Apr 21 to Apr 22
$305 total
Apr 21 - Apr 22
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,009 reviews)
Pet friendly, great layout if resort and room, convenient shuttle to nearby restaurants and activities

Reviewed on Apr 13, 2026

Opens in a new windowLa Siesta Resort & Villas
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4 out of 5
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$321 nightly
The price is $361 total per night from May 3 to May 4
$361 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,001 reviews)
Prepare for expensive meals and drinks.

Reviewed on Apr 3, 2026

Opens in a new windowTranquility Bay Beachfront Hotel and Resort
Villas At Hawks Cay Resort

Villas At Hawks Cay Resort

4 out of 5
61 Hawks Cay Boulevard Marathon FL
$814 nightly
The price is $916 total per night from May 2 to May 3
$916 total
May 2 - May 3
Total with taxes and fees
This luxury resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.2/10 Very Good! (191 reviews)
This property has a big effort to bring it up to the rate they charge. Needs maintenance, more staff, food quality is awful.

Reviewed on Apr 11, 2026

Opens in a new windowVillas At Hawks Cay Resort
Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club

4 out of 5
58182 Overseas Hwy Marathon FL
$298 nightly
The price is $335 total per night from May 12 to May 13
$335 total
May 12 - May 13
Total with taxes and fees
This smoke-free hotel features 2 outdoor pools, a hot tub, and a restaurant. Enjoy the sauna and perks like free self parking and free WiFi. There's a bar/lounge ...
9.4/10 Exceptional! (432 reviews)
Great rooftop bar with happy hour, live music and excellent food. Enjoyed the small but very pretty property.

Reviewed on Apr 13, 2026

Opens in a new windowGrassy Flats Resort & Beach Club
The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys

4 out of 5
6800 Overseas Hwy Marathon FL
This condo's 2 outdoor tennis courts and outdoor pool are among the featured amenities. Guests will appreciate free perks like free self parking and WiFi in ...
9.2/10 Wonderful! (24 reviews)
Our family loved it!

Reviewed on Apr 10, 2026

Opens in a new windowThe Reef at Marathon, Florida Keys
Marlin Bay Resort & Marina

Marlin Bay Resort & Marina

4.5 out of 5
3800 Gulfview Ave Marathon FL
A marina and an outdoor pool are featured at this luxury aparthotel. Enjoy the gym and perks like free self parking and a free airport shuttle. Free WiFi in ...
10/10 Exceptional! (2 reviews)
Wonderful vacation!

Reviewed on Jan 11, 2026

Opens in a new windowMarlin Bay Resort & Marina
Waterfront Luxury Villa

Waterfront Luxury Villa

4 out of 5
11600 1st Ave Gulf Marathon FL
An outdoor pool, free self parking, and laundry facilities are featured at this condo. WiFi in public areas is free. A garden, a picnic area, and concierge services ...
Opens in a new windowWaterfront Luxury Villa
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4 Star Hotels Duck Key

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Duck Key 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Duck Key will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Duck Key, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Duck Key hotel reviews by fellow wanderers

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