Book Hotels in Santa Isabel
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Santa Isabel hotels

Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
$147 nightly
The price is $161 total per night from Aug 12 to Aug 13
$161 total
Aug 12 - Aug 13
Total includes taxes and fees
An outdoor pool is featured at this hotel, along with a virtual front desk. Take advantage of the free self parking.
"I loved everything about the property and the staff was really friendly and always making sure we had what we needed"
Reviewed on Jul 1, 2025

Modern Cozy Home in Puerto Rican Paradise
Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, a water park, and an in-room coffeemaker. Popular attractions Carribbean Cinemas Santa Isabel and ...
Amazing stay
"This place was great and got the job done! Clarissa was not only super helpful but she was very accommodating and easy to contact. If we ever are back on that side of the island we will definitely be staying here again."
Reviewed on Apr 10, 2025

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
$343 nightly
The price is $364 total per night from Jul 20 to Jul 21
$364 total
Jul 20 - Jul 21
Total includes taxes and fees
A hot tub is featured at this vacation home, along with laundry facilities and concierge services. Barbecue grills are provided for your convenience.
Loved
"It was amazing to be in the center of the culture. Friendly neighbors! Food amazing! Beach’s all around I would definitely stay there again!!!"
Reviewed on Jun 15, 2025

Hilton Ponce Golf & Casino Resort
1150 Caribe Avenue, Ponce
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $254 total per night from Aug 11 to Aug 12
$254 total
Aug 11 - Aug 12
Total includes taxes and fees
This luxury resort features a golf course, free water park access, and a casino. Bring the family and enjoy the mini golf, children's pool, and waterslide. Enjoy ...
"everything is right there, refreshing environment and the employees are very nice and respectable"
Reviewed on Jul 9, 2025

Holiday Inn Ponce & Tropical Casino by IHG
3315 Ponce By Pass, Ponce
Fully refundable
$143 nightly
The price is $159 total per night from Aug 4 to Aug 5
$159 total
Aug 4 - Aug 5
Total includes taxes and fees
A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. A restaurant and a bar/lounge ...
"From the beginning to the end. The staff very friendly. The room very clean and smelling amazing from the hall way to the room. A guest laundry for your convenience. The pool very clean and beautiful. If you’re missing toothpaste or razors personal toiletries you can ask at the desk and they give ..."
Reviewed on Jul 7, 2025

Caribe Hotel Ponce
103 Turpo Industrial Park, Ponce
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $158 total per night from Jul 20 to Jul 21
$158 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self ...
"Las enpleadas fuero muy amables y pasé un buen fin de semana. Espero que al terminar toda la remodelación, tomen en consideración a los que lo hemos patrocinados y nos ofrezcan buenas ofertas."
Reviewed on Jul 10, 2025

Aloft Ponce Hotel & Casino
Street No 2 KM 228.9, Ponce
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $199 total per night from Aug 4 to Aug 5
$199 total
Aug 4 - Aug 5
Total includes taxes and fees
A casino, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Guests will appreciate free perks like free self parking and WiFi in ...
"Everything great"
Reviewed on Jul 8, 2025

Hotel Las Vegas
PR 153, Km 2.9, Santa Isabel
$92 nightly
The price is $100 total per night from Jul 21 to Jul 22
$100 total
Jul 21 - Jul 22
Total includes taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
"It was a nice getaway"
Reviewed on Jun 25, 2025

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel
This vacation home featured laundry facilities and barbecue grills.
Unforgettable Family Vacation at Mimi’s Stunning VRBO!
"Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to ..."
Reviewed on Jun 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Isabel hotel reviews by fellow wanderers

The Fox Hotel
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Good to hotel, very fun and clean. Thank you so much"
A verified traveler stayed at The Fox Hotel
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
Accommodation Types
An Attraction
- Hotels near La Guancha
- Hotels near Coamo Springs
- Hotels near Hacienda Buena Vista
- Hotels near Albergue Olimpico
- Hotels near El Museo Castillo Serralles
- Hotels near Marina de Salinas
- Hotels near Plaza of Delights
- Hotels near Toro Negro State Forest
- Hotels near El Vigia Hill
- Hotels near Cardona Island Light
- Hotels near Tres Picachos
- Hotels near Reserva Nacional de Investigación Estuarina de Bahía de Jobos
- Hotels near Bosque Estatal De Carite
- Hotels near Museo de Arte de Ponce
- Hotels near San Cristobal Canyon
- Hotels near Museum of the Ponce Massacre
- Ponce Hotels
- Caribbean Islands Hotels
- Puerto Rico Island Hotels
- Salinas Hotels
- Caguas Hotels
- Utuado Hotels
- Juana Diaz Hotels
- Guayama Hotels
- Adjuntas Hotels
- Jayuya Hotels
- Patillas Hotels
- Penuelas Hotels
- Cayey Hotels
- Barranquitas Hotels
- Ciales Hotels
- Orocovis Hotels
- Cidra Hotels
- Coamo Hotels
- Aibonito Hotels
- Comerio Hotels
- Aguas Buenas Hotels
- Arroyo Hotels
- Corozal Hotels
- Morovis Hotels
- Naranjito Hotels
- Villalba Hotels
- Playa Hotels
- Aguirre Hotels
- Toro Negro Hotels
- San Antón Hotels
- Canas Hotels
- Tercero Hotels
- Jobos Hotels
- Segundo Hotels
- Palmas Hotels
- Lapa Hotels
- Bayamón Hotels
- Machete Hotels
Most popular
Hotels
Flights
Cars
Activities