Book Hotels in Santa Isabel
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Top Santa Isabel hotels

Seaside Serenity – Oceanfront Villa with Infinity Pool & Garden Sanctuary
Santa Isabel PR
$551 nightly
The price is $584 total per night from Nov 19 to Nov 20
$584 total
Nov 19 - Nov 20
Total with taxes and fees
This vacation home includes a garden and barbecue grills.
Such an amazing place. Views are spectacular. The outside family area was our favorite part. The pool was perfect too. My family and I were very comfortable here. Definitely look forward to coming back!
Reviewed on Oct 7, 2025

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Santa Isabel Santa Isabel
$486 nightly
The price is $516 total per night from Nov 17 to Nov 18
$516 total
Nov 17 - Nov 18
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
Unforgettable Family Vacation at Mimi’s Stunning VRBO!
Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to ...
Reviewed on Jun 2, 2025

Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$160 nightly
The price is $175 total per night from Dec 14 to Dec 15
$175 total
Dec 14 - Dec 15
Total with taxes and fees
An outdoor pool is featured at this hotel, along with a virtual front desk. Take advantage of the free self parking.
Perfect stay. Stunning views. Delicous food and great bar on site. Pool was nice. Everything was extremely clean, all staff was amazing. San juan only an hour away, Orocovis is super close to. 10/10 will be staying here again
Reviewed on Sep 7, 2025

Modern Cozy Home in Puerto Rican Paradise
Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, a water park, and an in-room coffeemaker. Popular attractions Carribbean Cinemas Santa Isabel and ...
Amazing stay
This place was great and got the job done! Clarissa was not only super helpful but she was very accommodating and easy to contact. If we ever are back on that side of the island we will definitely be staying here again.
Reviewed on Apr 10, 2025

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
$341 nightly
The price is $362 total per night from Nov 23 to Nov 24
$362 total
Nov 23 - Nov 24
Total with taxes and fees
A hot tub is featured at this vacation home, along with laundry facilities and concierge services. Barbecue grills are provided for your convenience.
Loved it!!!!! Spacious clean! Internet did not work but to be honest we did not need it at all.
Reviewed on Sep 7, 2025

Hilton Ponce Golf & Casino Resort
1150 Caribe Avenue Ponce
Fully refundableReserve now, pay when you stay
$178 nightly
The price is $197 total per night from Nov 23 to Nov 24
$197 total
Nov 23 - Nov 24
Total with taxes and fees
This luxury resort features a golf course, free water park access, and a casino. Bring the family and enjoy the mini golf, children's pool, and waterslide. Enjoy ...
Breakfast was great.
Reviewed on Nov 13, 2025

Aloft Ponce Hotel & Casino
Street No 2 KM 228.9 Ponce
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $188 total per night from Nov 17 to Nov 18
$188 total
Nov 17 - Nov 18
Total with taxes and fees
A casino, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Guests will appreciate free perks like free self parking and WiFi in ...
Yes
Reviewed on Nov 14, 2025

Caribe Hotel Ponce
103 Turpo Industrial Park Ponce
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $162 total per night from Nov 17 to Nov 18
$162 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self ...
The hotel was under construction but it’s coming out nice
Reviewed on Nov 14, 2025

Hotel Las Vegas
PR 153, Km 2.9 Santa Isabel
$92 nightly
The price is $100 total per night from Nov 24 to Nov 25
$100 total
Nov 24 - Nov 25
Total with taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
Good thing Walmart nearby
Reviewed on Nov 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Isabel hotel reviews by fellow wanderers
Caribe Hotel Ponce
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The hotel was under construction but it’s coming out nice "
A verified traveler stayed at Caribe Hotel Ponce
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