Book Hotels in Santa Isabel

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Santa Isabel hotels

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2

Santa Isabel PR
$539 nightly
The price is $572 total per night from Jul 28 to Jul 29
$572 total
Jul 28 - Jul 29
Total with taxes and fees
This villa includes a garden and barbecue grills.
"Absolutely beautiful the pictures do not do justice for the breath taking view. The host was more than attentive and was very easy to get ahold of. Overall beautiful stay, definitely would come back."

Reviewed on Jun 29, 2026

Opens in a new windowRomantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
Salinas Blue House 2 in the Beach, Private Pool

Salinas Blue House 2 in the Beach, Private Pool

Santa isabel Puerto Rico
A hot tub is featured at this vacation home, along with laundry facilities and barbecue grills.
"Hector was a great host!! The home is beautiful and would stay again. The downstairs bedroom was perfect for my Dad who is 83."

Reviewed on Apr 23, 2026

Get rates
Opens in a new windowSalinas Blue House 2 in the Beach, Private Pool
3BR Puerto Rico Villa w Pool | Aqua Bella 1

3BR Puerto Rico Villa w Pool | Aqua Bella 1

Santa Isabel PR
This vacation home includes a garden and barbecue grills.
"Fantastic stay with my family. It’s a beautiful property with incredible views. The pool was amazing and the kids really enjoyed their time here. The host was great and very responsive. The property was very clean and secure. We would definitely stay here again!!"

Reviewed on Jun 8, 2026

Get rates
Opens in a new window3BR Puerto Rico Villa w Pool | Aqua Bella 1
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$113 nightly
The price is $123 total per night from Aug 3 to Aug 4
$123 total
Aug 3 - Aug 4
Total with taxes and fees
An outdoor pool, free self parking, and a virtual front desk are featured at this hotel. A garden is also provided.
"Beautiful clean room"

Reviewed on Jul 26, 2026

Opens in a new windowHacienda del Sur
Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, an in-room coffeemaker, and air conditioning. Popular attractions Carribbean Cinemas Santa Isabel ...
"Yes thank you letting stay in this place. Very quiet for most of the time and I am new to this area even after growing up here. Everything was great however the house needs some checking because there are some ants and few cockroaches around the house. Also check the shower drain. Besides that every ..."

Reviewed on Jul 5, 2026

Get rates
Opens in a new windowModern Cozy Home in Puerto Rican Paradise
Gorgeous Place with Pool and Patio

Gorgeous Place with Pool and Patio

Santa Isabel Santa Isabel
$237 nightly
The price is $252 total per night from Aug 2 to Aug 3
$252 total
Aug 2 - Aug 3
Total with taxes and fees
An outdoor pool is featured at this bed & breakfast, along with barbecue grills.
Family getaway
"Maria was great! She was very responsive when we needed something. She also communicated with us when there was going to be cleaning done in the pool. Overall the place was clean. The pool was amazing and it was great that we had it all to ourselves."

Reviewed on Apr 26, 2021

Opens in a new windowGorgeous Place with Pool and Patio
Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9 Santa Isabel
$83 nightly
The price is $91 total per night from Jul 27 to Jul 28
$91 total
Jul 27 - Jul 28
Total with taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
"Bueno"

Reviewed on Jul 23, 2026

Opens in a new windowHotel Las Vegas
Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views

Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views

santa isabel puerto rico
Stay at this villa in Santa Isabel. Enjoy patios and air conditioning. Popular attractions Playa La Ochenta and Marina de Salinas are located nearby.
"Host never contacted us we found the house on our own absolute dump , didn’t stay went somewhere else"

Reviewed on Feb 13, 2026

Get rates
Opens in a new windowBeachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
$341 nightly
The price is $362 total per night from Jul 27 to Jul 28
$362 total
Jul 27 - Jul 28
Total with taxes and fees
Laundry facilities, concierge services, and barbecue grills are available at this vacation home.
Opens in a new windowCultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Isabel?
Book a stay at Beautiful Unique and Peaceful Farm Wood Cabin and make vacationing with the youngsters super simple. This popular option in Santa Isabel offers amenities designed to make family trips easier, such as a swimming pool.
Where can I find cheap hotels in Santa Isabel?
At Travelocity you'll find really nice hotels in Santa Isabel at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Isabel rather than in Santa Isabel. We may find you even better rates, too.
How do I find the best Santa Isabel hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Isabel then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Isabel?
The cheapest hotel in Santa Isabel is $91. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Isabel?
There are 320 hotels in Santa Isabel on Travelocity.
What are the best hotels in Santa Isabel?
Santa Isabel has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Isabel for you!
When is the best time to visit Santa Isabel?
If you want the joy of a fun-filled trip in peak season, visit Santa Isabel during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Isabel?
Based on historic data is usually the cheapest month to visit Santa Isabel. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Isabel?
There are multiple hotels in Santa Isabel that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Isabel. We have plenty of kid-friendly hotels in Santa Isabel to choose from on Travelocity!
Why book a hotel in Santa Isabel through Travelocity?
Because we have the top hotels in Santa Isabel! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Isabel on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Isabel hotel reviews by fellow wanderers

Spark by Hilton Ponce

Spark by Hilton Ponce

4 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Todo bien bueno…lo único que deberían de tener es donde comer dentro del hotel !! De lo demás muy bueno y tranquilo ! Personal muy amable"
A verified traveler stayed at Spark by Hilton Ponce
Spark by Hilton Ponce

Explore More Ways to Travel with Travelocity