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Top hotels in Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $200 total per night from Sep 30 to Oct 1
$200 total
Sep 30 - Oct 1
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"On the first night, i noticed an ant on my nightstand. Made me think there was a pile of them waiting to be discovered in the room. The phone made this weird humming noise. Sounded similar to dial-up. We unplugged it every night so we could sleep. There was a card in the room that instructed guests ..."

Reviewed on Sep 29, 2026

Opens in a new windowLegacy Resort Hotel & Spa
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
$130 nightly
The price is $150 total per night from Oct 12 to Oct 13
$150 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"I loved the patio. There was a large big pool clean, the fireplace and the Jacuzzi was my favorite. We did a lot of walking and my body was so sore and it felt really good to sit in the hot tub. The staff was very accommodating and the breakfast was very good. Everyone was friendly. I loved it here. ..."

Reviewed on Sep 29, 2026

Opens in a new windowHampton Inn San Diego/Mission Valley
Town and Country San Diego

Town and Country San Diego

4 out of 5
500 Hotel Circle North San Diego CA
Fully refundableReserve now, pay when you stay
$268 nightly
The price is $308 total per night from Sep 30 to Oct 1
$308 total
Sep 30 - Oct 1
Total with taxes and fees
This hotel features 2 restaurants, 2 outdoor pools, and a hot tub. Bring the family and enjoy the children's pool, waterslide, and playground. Enjoy the gym ...
"Very cool vibe! Food was delicious, & market coffees yummy-I recommend iced honey lavender. Only negative was our fire pit on our patio only worked 1 time our entire stay. Maintenance worked on it a couple of times, but never got it back in working order during our stay."

Reviewed on Sep 29, 2026

Opens in a new windowTown and Country San Diego
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

3.5 out of 5
2270 Hotel Cir N San Diego CA
Fully refundable
$114 nightly
The price is $131 total per night from Oct 5 to Oct 6
$131 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Balcony view, friendly staff and clean room"

Reviewed on Sep 29, 2026

Opens in a new windowCrowne Plaza San Diego - Mission Valley by IHG
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
$85 nightly
The price is $97 total per night from Sep 30 to Oct 1
$97 total
Sep 30 - Oct 1
Total with taxes and fees
2 hot tubs, an outdoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi ...
Opens in a new windowBest Western Seven Seas
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
$103 nightly
The price is $119 total per night from Sep 30 to Oct 1
$119 total
Sep 30 - Oct 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
Opens in a new windowHandlery Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S San Diego CA
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Oct 12 to Oct 13
$97 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub ...
Opens in a new windowDays Inn by Wyndham San Diego Hotel Circle
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

2.5 out of 5
San Diego CA
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $104 total per night from Oct 28 to Oct 29
$104 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel features an outdoor pool and a gym. Guests will appreciate free perks like continental breakfast and WiFi in public areas. Self parking, a garden, ...
Opens in a new windowThe Alcala Hotel Mission Valley/Seaworld
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S San Diego CA
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $105 total per night from Oct 4 to Oct 5
$105 total
Oct 4 - Oct 5
Total with taxes and fees
This Art Deco hotel includes 2 restaurants, an outdoor pool, and a hot tub. Enjoy the gym and perks like free WiFi. A bar/lounge, a 24-hour front desk, and a ...
Opens in a new windowKings Inn San Diego
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mission Valley Hotel Guide\n

Hotels in Mission Valley, San Diego, put you in the heart the city's Old Town, a place with an unparalleled role in the history of the American West. It's the site of the first Spanish settlement in California, where some of the oldest buildings in the state still stand, but today's Mission Valley also draws in visitors as a prime entertainment and shopping district. Find a San Diego flight today for a journey into California history.

Mission Valley

The ruins that remain of the Presidio of San Diego, which was established in 1769, are in Presidio Park, a four-acre green space and National Historic Landmark overlooking Mission Valley. The original site is now marked by the Junipero Serra Museum, where you can learn about this earliest of all Spanish settlements in the state. Mission Valley hotels also put you close to the Old Town San Diego Historic Park, where preserved historic buildings from 1820 to 1870 show you what life was like in San Diego long before it became a destination for beach-seeking tourists. See stores, a stable, a schoolhouse, a blacksmith's shop, and a newspaper office. This desirable area of San Diego doesn't just appeal to history buffs. Book a vacation to San Diego for the whole family and take the kids to SeaWorld, located on the edge of Mission Valley. The valley ends at Mission Bay, a saltwater lagoon surrounded by the largest aquatic park in the country. Wander its pedestrian pathways, or take to the water with a sailing, jet-skiing, or wakeboarding excursion. And you can add shopping to your itinerary: Westfield Mission Valley and Fashion Valley Mall are just two of the area's major retail destinations.

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