Book Hotels in Depew, NY
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Top Depew hotels
Holiday Inn Express Grand Island - Niagara Falls by IHG
Breakfast was fresh
Reviewed on Apr 10, 2026
Wyndham Garden Buffalo Downtown
Our stay was very comfortable. The staff were very courteous and professional.
Reviewed on Apr 10, 2026
Hyatt Place Buffalo/Amherst
Intuitively comfortable and accommodating. I would expect to pay much more for such a great stay.
Reviewed on Apr 8, 2026
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
We purposely booked this motel because we had a very early flight the next day AND we were happy to use the airport shuttle, which was very prompt, professional and protective. When our driver was pulling into the airport, he patiently waited for a good curbside parking spot and was very insistent ...
Reviewed on Apr 8, 2026
Buffalo Airport Hotel
Probably the most comfortable hotel bed I've ever slept on. Room was clean and had all I needed to sleep and shower as I was there only about 10 hours. However, the hallways desperately needed to be vacuumed and I could hear people just hanging out in the hall talking at 10pm and someone stomping ...
Reviewed on Apr 9, 2026
Sleep Inn & Suites Buffalo Airport
The building and rooms are old and dirty. The staff is okay, not so friendly. Breakfast is terrible.
Reviewed on Apr 9, 2026
Garden Place Hotel
There was an employee during our stay who tried to steal money from us during our check in. The safety deposit was $150. I gave the employee 2 $100 bills. She took one of the $100 bills I gave her, put it in a drawer, took a $50 bill out of the drawer and put it along with my other $100 bill into ...
Reviewed on Apr 9, 2026
M Hotel Buffalo
The Staff Was Quite Accommodating During My Stay
Reviewed on Apr 8, 2026
Hyatt Regency Buffalo / Hotel and Conference Center
Depew Hotel & Travel Guide\n
If you're thinking of exploring the Buffalo area and are looking for a place to stay in Depew, Travelocity offers an exciting assortment to decide between. Inside the resourceful booking pages, the modern traveler will find 50 flexible accommodation options within a 6-mile (10-kilometer) distance of Depew's center.
Visitors searching for a hotel in the heart of Depew should plan to stay at Pink Fountain Motor Inn.
9 miles (14 kilometers) from the town center of Depew, you will find the The Mansion On Delaware Ave. Alternatively, the Lofts on Pearl is positioned 9 miles (14 kilometers) away. Other possible Travelocity-listed hotels are the Hampton Inn & Suites Buffalo Downtown and the Hotel @ The Lafayette.
After you have seen Depew, put aside some time to investigate the other natural and cultural attractions of the Niagara Falls - Western New York area. Get to know Niagara Falls - Western New York's art galleries and theaters. You should also make the time to admire its lakes. Wise visitors in this part of United States of America will enjoy ice skating and guided nature walks.
8 miles (12 kilometers) to the west of Depew, you can reach Downtown Buffalo, home to Greater Buffalo Sports Hall of Fame and Old Erie County Hall. Some of our recommended Downtown Buffalo hotels and accommodations include the Embassy Suites Buffalo and Hyatt Regency Buffalo / Hotel and Conference Center. 9 miles (15 kilometers) to the northwest of Depew, you can also stay at Amherst, home to the Homewood Suites by Hilton Buffalo/Amherst and Residence Inn Buffalo Amherst. Should you choose to stay in Amherst, set aside some time to explore the Boulevard Mall and Lasertron.
Simply because you and your traveling partners are taking a break from your usual habits, who says you can't enjoy your passion for a day of sports. You can find First Niagara Center 9 miles (14 kilometers) to the west of Depew. Sleep right in the thick of the sporting action at the Holiday Inn Buffalo-Downtown or the Holiday Inn Express & Suites Buffalo Downtown.
For travelers flying through Buffalo Niagara International Airport, you may like to book some accommodation at Staybridge Suites Buffalo-Airport, or Hilton Garden Inn Buffalo Airport, each of which are conveniently located nearby.
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Recent Depew hotel reviews by fellow wanderers
Wyndham Garden Buffalo Downtown
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