Book Hotels in Depew, NY
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Top Depew hotels
Holiday Inn Express Grand Island - Niagara Falls by IHG
This was an excellent place to stay while visiting Canada only 6 miles away. Jamal at front desk was very friendly and helpful as were all the staff. Breakfast was delicious.
Reviewed on Oct 24, 2025
Wyndham Garden Buffalo Downtown
The staff was friendly and helpful. The room, though clean, did show some signs of wear and tear, though not hugely obvious. Room temperature was able to be kept comfortable. Little noisy outside our room early in the morning and onward from some construction happening behind the building. Not the ...
Reviewed on Oct 23, 2025
La Quinta Inn & Suites by Wyndham Buffalo Amherst
The stay was fine, the hotel was very clean as was the room. Bed was very comfortable and the air conditioner worked. The only thing that I would suggest is a little more variety for breakfast options. Other than that the stay was great.
Reviewed on Oct 19, 2025
Hyatt Regency Buffalo / Hotel and Conference Center
Went there for the hockey game. Trolley is just outside the door and free to go to the game. Good location. All you need
Reviewed on Oct 25, 2025
Buffalo Airport Hotel
Airport shuttle was great and the wing restraunts was great Check in was flawless
Reviewed on Oct 21, 2025
Sleep Inn & Suites Buffalo Airport
Close to the airport. Staff is great.Good choices for breakfast.
Reviewed on Oct 24, 2025
Garden Place Hotel
Great place to get away...
Reviewed on Oct 25, 2025
Days Inn & Suites by Wyndham Niagara Falls/Buffalo
There was no hot tub
Reviewed on Oct 20, 2025
M Hotel Buffalo
Close to shopping and a variety of other activities.
Reviewed on Oct 24, 2025
Depew Hotel & Travel Guide\n
If you're thinking of exploring the Buffalo area and are looking for a place to stay in Depew, Travelocity offers an exciting assortment to decide between. Inside the resourceful booking pages, the modern traveler will find 50 flexible accommodation options within a 6-mile (10-kilometer) distance of Depew's center.
Visitors searching for a hotel in the heart of Depew should plan to stay at Pink Fountain Motor Inn.
9 miles (14 kilometers) from the town center of Depew, you will find the The Mansion On Delaware Ave. Alternatively, the Lofts on Pearl is positioned 9 miles (14 kilometers) away. Other possible Travelocity-listed hotels are the Hampton Inn & Suites Buffalo Downtown and the Hotel @ The Lafayette.
After you have seen Depew, put aside some time to investigate the other natural and cultural attractions of the Niagara Falls - Western New York area. Get to know Niagara Falls - Western New York's art galleries and theaters. You should also make the time to admire its lakes. Wise visitors in this part of United States of America will enjoy ice skating and guided nature walks.
8 miles (12 kilometers) to the west of Depew, you can reach Downtown Buffalo, home to Greater Buffalo Sports Hall of Fame and Old Erie County Hall. Some of our recommended Downtown Buffalo hotels and accommodations include the Embassy Suites Buffalo and Hyatt Regency Buffalo / Hotel and Conference Center. 9 miles (15 kilometers) to the northwest of Depew, you can also stay at Amherst, home to the Homewood Suites by Hilton Buffalo/Amherst and Residence Inn Buffalo Amherst. Should you choose to stay in Amherst, set aside some time to explore the Boulevard Mall and Lasertron.
Simply because you and your traveling partners are taking a break from your usual habits, who says you can't enjoy your passion for a day of sports. You can find First Niagara Center 9 miles (14 kilometers) to the west of Depew. Sleep right in the thick of the sporting action at the Holiday Inn Buffalo-Downtown or the Holiday Inn Express & Suites Buffalo Downtown.
For travelers flying through Buffalo Niagara International Airport, you may like to book some accommodation at Staybridge Suites Buffalo-Airport, or Hilton Garden Inn Buffalo Airport, each of which are conveniently located nearby.
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Recent Depew hotel reviews by fellow wanderers
Hyatt Regency Buffalo / Hotel and Conference Center
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