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Top hotels in East Seneca

Tru by Hilton Williamsville Buffalo Airport

Tru by Hilton Williamsville Buffalo Airport

2.5 out of 5
48 Freeman Road Buffalo NY
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from Apr 5 to Apr 6
$120 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Relax with a drink at the bar/lounge and enjoy free perks like self-serve breakfast and free self parking. A business ...
Loved the breakfast. The staff was very friendly!

Reviewed on Mar 16, 2026

Opens in a new windowTru by Hilton Williamsville Buffalo Airport
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 out of 5
601 Main St Buffalo NY
Fully refundable
$104 nightly
The price is $121 total per night from Apr 5 to Apr 6
$121 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Very close to the theatre where we got to watch Riverdance! Memorable experience.

Reviewed on Mar 19, 2026

Opens in a new windowHoliday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
Holiday Inn Express Cheektowaga North East by IHG

Holiday Inn Express Cheektowaga North East by IHG

2.5 out of 5
83 Anderson Rd Buffalo NY
Fully refundable
$119 nightly
The price is $135 total per night from Apr 12 to Apr 13
$135 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Pool water was barely warm, but the room itself was quite cold. Got a room specifically to swim with my grandbaby, was disappointed. Room was clean and nice.

Reviewed on Mar 23, 2026

Opens in a new windowHoliday Inn Express Cheektowaga North East by IHG
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $167 total per night from Mar 29 to Mar 30
$167 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
too hot in the room. could not adjust the temperature satisfactorily

Reviewed on Mar 23, 2026

Opens in a new windowHyatt Regency Buffalo / Hotel and Conference Center
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 out of 5
131 Buell Ave Buffalo NY
Fully refundable
$104 nightly
The price is $118 total per night from Apr 19 to Apr 20
$118 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Good sized rooms, great for a quick night stay before a flight

Reviewed on Mar 23, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Buffalo-Airport by IHG
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $97 total per night from Mar 26 to Mar 27
$97 total
Mar 26 - Mar 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Clean comfortable room. Great atmosphere at the bar. Breakfast in the morning would be nice. Convenient location near the airport.

Reviewed on Mar 23, 2026

Opens in a new windowBuffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundable
$75 nightly
The price is $85 total per night from Apr 21 to Apr 22
$85 total
Apr 21 - Apr 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
Clean room but common areas werenoo

Reviewed on Mar 24, 2026

Opens in a new windowSleep Inn & Suites Buffalo Airport
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $90 total per night from Mar 29 to Mar 30
$90 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a 24-hour gym and a sauna. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
The hotel is changing hands and there are some improvements needed but they are working on them. My only complaint the phone number listed is not a direct line to hotel and they advertise contential breakfast but its a pay for breakfast

Reviewed on Mar 24, 2026

Opens in a new windowGarden Place Hotel
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Mar 29 to Mar 30
$96 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
Beautiful Stay

Reviewed on Mar 23, 2026

Opens in a new windowM Hotel Buffalo
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Seneca Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Seneca area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Seneca to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Seneca are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Seneca hotel reviews by fellow wanderers

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