Explore top 2025 4 Star Hotels in Duck Key

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Top Duck Key 4 Star hotels

Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd, Marathon, FL
Fully refundableReserve now, pay when you stay
$368 nightly
The price is $413 total per night from Oct 12 to Oct 13
$413 total
Oct 12 - Oct 13
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8/10 Very Good! (1,012 reviews)
Great family vacation stay in villa
"Amazing views and villas are great for family vacation stays. Wonderful balconies Beautiful resort overall."

Reviewed on Sep 28, 2025

Opens in a new windowHawks Cay Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy, Islamorada, FL
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $210 total per night from Oct 14 to Oct 15
$210 total
Oct 14 - Oct 15
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
8.8/10 Excellent! (1,252 reviews)
"We had a room with an ocean view and it was great. There was a beautiful double rainbow over the water one of the days we were there."

Reviewed on Oct 4, 2025

Opens in a new windowAmara Cay Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4 out of 5
2600 Overseas Hwy, Marathon, FL
Fully refundableReserve now, pay when you stay
$281 nightly
The price is $317 total per night from Oct 26 to Oct 27
$317 total
Oct 26 - Oct 27
Total with taxes and fees
This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...
8.8/10 Excellent! (1,001 reviews)
"Me encantó en todos los sentidos. Volvería con toda seguridad."

Reviewed on Sep 25, 2025

Opens in a new windowTranquility Bay Beachfront Hotel and Resort
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway, Islamorada, FL
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $195 total per night from Oct 13 to Oct 14
$195 total
Oct 13 - Oct 14
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
8.6/10 Excellent! (1,001 reviews)
"Great rooms"

Reviewed on Sep 20, 2025

Opens in a new windowLa Siesta Resort & Villas
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4 out of 5
1996 Overseas Highway, Marathon, FL
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $215 total per night from Oct 15 to Oct 16
$215 total
Oct 15 - Oct 16
Total with taxes and fees
A marina, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free resort. Traveling on business? Take advantage of the 3 conference rooms, along ...
8.8/10 Excellent! (1,274 reviews)
"Well maintained, friendly staff. No microwave in room."

Reviewed on Sep 29, 2025

Opens in a new windowFaro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Villas At Hawks Cay Resort

Villas At Hawks Cay Resort

4 out of 5
61 Hawks Cay Boulevard, Villas, Marathon, FL
This luxury resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
8.4/10 Very Good! (136 reviews)
"It was slow season so a lot of things were closed in the area but overall is a great place"

Reviewed on Sep 24, 2025

Opens in a new windowVillas At Hawks Cay Resort
Marlin Bay Resort & Marina

Marlin Bay Resort & Marina

4 out of 5
3800 Gulfview Ave, Marathon, FL
A marina and an outdoor pool are featured at this smoke-free condo resort. Enjoy the gym and perks like free self parking and a free airport shuttle. Free WiFi ...
Opens in a new windowMarlin Bay Resort & Marina
The Reef at Marathon, Florida Keys

The Reef at Marathon, Florida Keys

4 out of 5
6800 Overseas Hwy, Marathon, FL
This condo's 2 outdoor tennis courts and outdoor pool are among the featured amenities. Guests will appreciate free perks like free self parking and WiFi in ...
9.2/10 Wonderful! (8 reviews)
"It’s always been my favorite. The villas fit all my needs. Fantastic location and friendly staff."

Reviewed on May 31, 2025

Opens in a new windowThe Reef at Marathon, Florida Keys
Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

Palm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen

4 out of 5
Key Colony Beach
This vacation home features an outdoor pool and a hot tub. Laundry facilities and barbecue grills are also provided.
Opens in a new windowPalm View 5 BR Pool, Dock KCB, Cabana Club, Outdoor Kitchen
Key Colony Beach Paradise

Key Colony Beach Paradise

4 out of 5
Key Colony Beach
An outdoor pool is featured at this vacation home, along with laundry facilities and barbecue grills.
10/10 Exceptional! (3 reviews)
Great house!!!!!
"We loved this property. The boat dock is so large and we really appreciate the bumpers to protect the boat. Plenty of seating around the pool. The afternoon sun really heats that side of the street so the pool was very warm - still refreshing. The beds are super comfortable and the house is laid ..."

Reviewed on Jun 26, 2022

Opens in a new windowKey Colony Beach Paradise
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4 Star Hotels Duck Key

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Duck Key 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Duck Key will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Duck Key, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Duck Key hotel reviews by fellow wanderers

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