Explore top 2026 4 Star Hotels in Duck Key

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top Duck Key 4 Star hotels

Amara Cay Resort

80001 Overseas Hwy Islamorada FL

$224 nightly

$252 total

Aug 30 - Aug 31

Total with taxes and fees

A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...

Hawks Cay Resort

61 Hawks Cay Blvd Marathon FL

Fully refundableReserve now, pay when you stay

$288 nightly

$322 total

Aug 10 - Aug 11

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...

8.2/10 Very Good! (1,011 reviews)

"We had a great stay at Hawks Cay! Staff are all lovely and helpful. We had an issue yesterday as towels were taken during housekeeping service but not replaced. I reported this to reception but unfortunately this was not followed up. Lady at reception was very kind this morning apologising."

Reviewed on Aug 4, 2026

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

1996 Overseas Highway Marathon FL

Fully refundableReserve now, pay when you stay

$193 nightly

$217 total

Aug 9 - Aug 10

Total with taxes and fees

This smoke-free resort features a full-service spa, a marina, and 4 restaurants. Traveling on business? Take advantage of the 3 conference rooms, along with ...

8.6/10 Excellent! (1,166 reviews)

"This is the second time I've been to this hotel and surely I will be back. The property is just gorgeous and so user friendly. The pool by the ocean is great if you want to chat with other guests, have a drink and listen to mellow live music in a true Florida Keys way. The back pool is great if you ..."

Reviewed on Aug 3, 2026

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy Marathon FL

Fully refundableReserve now, pay when you stay

$264 nightly

$297 total

Aug 25 - Aug 26

Total with taxes and fees

This smoke-free hotel features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy ...

8.8/10 Excellent! (1,000 reviews)

"Todo muy bonito, el personal de servicio muy amable"

Reviewed on Aug 4, 2026

La Siesta Resort & Villas

80241 Overseas Highway Islamorada FL

$237 nightly

$266 total

Aug 9 - Aug 10

Total with taxes and fees

The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...

8.6/10 Excellent! (1,003 reviews)

"The check in staff was amazing and helpful. There was a lot of included things to do that were really nice and easy to access. There was a strong fish smell, but that was likely because people catch/clean their fish at the dock and there was a bit of sea grass along the shore that likely contributed. ..."

Reviewed on Aug 3, 2026

Grassy Flats Resort & Beach Club

58182 Overseas Hwy Marathon FL

$200 nightly

$225 total

Sep 3 - Sep 4

Total with taxes and fees

This smoke-free hotel features 2 outdoor pools, a hot tub, and a restaurant. Enjoy the sauna and perks like free self parking and free WiFi. There's a bar/lounge ...

9.4/10 Exceptional! (481 reviews)

"Wish the AC was better. Amazing staff all around. Comfortable. A true beauty"

Reviewed on Aug 3, 2026

Villas At Hawks Cay Resort

61 Hawks Cay Boulevard Marathon FL

Fully refundableReserve now, pay when you stay

$758 nightly

$852 total

Sep 3 - Sep 4

Total with taxes and fees

This luxury resort features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...

Marlin Bay Resort & Marina

3800 Gulfview Ave Marathon FL

A marina and an outdoor pool are featured at this luxury aparthotel. Enjoy the gym and perks like free self parking and a free airport shuttle. Free WiFi in ...

10/10 Exceptional! (3 reviews)

"Everything was perfection during our week there."

Reviewed on Apr 17, 2026

Get rates

Waterfront Luxury Villa

11600 1st Ave Gulf Marathon FL

An outdoor pool, free self parking, and laundry facilities are featured at this condo. WiFi in public areas is free. A garden, a picnic area, and concierge services ...

Get rates

Oceanfront Duck Key Villa: 2 Marinas Steps Away!

Marathon FL

This apartment features a marina and free WiFi in public areas.

Get rates

Don't see what you're looking for?

See all available properties in Duck Key

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Duck Key

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Duck Key 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Duck Key will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Duck Key, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.