Book Cheap Hotels in San Diego Santa Fe Depot, CA
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Top San Diego Santa Fe Depot hotels

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.06 mi from San Diego Santa Fe Depot
$119 nightly
The price is $137 total per night
$137 total
Jul 21 - Jul 22
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and visit the 2 bars/lounges and poolside bar for drinks.

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.26 mi from San Diego Santa Fe Depot
$169 nightly
The price is $195 total per night
$195 total
Jul 27 - Jul 28
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and free airport shuttle. There's a bar/lounge on site, and concierge services and free newspapers are also provided.

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.43 mi from San Diego Santa Fe Depot
$222 nightly
The price is $257 total per night
$257 total
Jul 21 - Jul 22
Total includes taxes and fees
This eco-certified hotel includes 6 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the hot tub and visit the 3 bars/lounges and poolside bar for drinks.

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
5.25 mi from San Diego Santa Fe Depot
$170 nightly
The price is $196 total per night
$196 total
Aug 18 - Aug 19
Total includes taxes and fees
A marina, 2 outdoor pools, and 2 hot tubs are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and visit the 2 poolside bars and bar/lounge for drinks.

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.53 mi from San Diego Santa Fe Depot
$259 nightly
The price is $300 total per night
$300 total
Aug 17 - Aug 18
Total includes taxes and fees
This smoke-free hotel features a full-service spa, a marina, and 5 restaurants. Families will appreciate the children's pool and onsite laundry facilities. Enjoy the 2 outdoor pools and perks like free WiFi.
Pool
Hot Tub

The Dextro Hotel, BW Premier Collection
1617 1st Avenue, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.54 mi from San Diego Santa Fe Depot
$135 nightly
The price is $157 total per night
$157 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a 24-hour gym on site, and a 24-hour front desk and express check-out are also provided.
Pool
Free WiFi

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.28 mi from San Diego Santa Fe Depot
$170 nightly
The price is $195 total per night
$195 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub and free full breakfast each morning.

The Little Italy Hotel Downtown San Diego
1646 Front St, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.48 mi from San Diego Santa Fe Depot
$148 nightly
The price is $171 total per night
$171 total
Jul 28 - Jul 29
Total includes taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Self parking is offered and multilingual staff can provide around-the-clock assistance.

Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.21 mi from San Diego Santa Fe Depot
$131 nightly
The price is $151 total per night
$151 total
Aug 10 - Aug 11
Total includes taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. You'll appreciate the outdoor pool, bar/lounge, and laundry facilities.
Pool
Hot Tub
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See all available properties in San Diego Santa Fe Depot
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
San Diego Santa Fe Depot hotels essential information
Accommodation | 3,688 hotels |
---|---|
Lowest Price | $137 |
Highest Price | $300 |
Popular hotels | Handlery Hotel, Wyndham San Diego Bayside, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Marriott Marquis San Diego Marina, The Dextro Hotel, BW Premier Collection, Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , The Little Italy Hotel Downtown San Diego, Bay Club Hotel & Marina |
Recent San Diego Santa Fe Depot hotel reviews by fellow wanderers

The Dana on Mission Bay
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Na"
A verified traveler stayed at The Dana on Mission Bay
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