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Top Southeast Minnesota hotels

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from Jun 27 to Jun 28
$195 total
Jun 27 - Jun 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Staff were uniformly friendly and helpful. That made all the difference for us since we were commuting to/from Mayo Clinic. The free breakfast was decent, but lacked variety, wearing thin during our 1 week stay. Trash was not emptied nearly often enough from the small bins near the elevators. Also ..."

Reviewed on Jun 19, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Treasure Island Resort & Casino

Treasure Island Resort & Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jun 28 to Jun 29
$105 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
"Staff was rude!! Bed had a bloody tissue covered up! Will never ever go there again"

Reviewed on Jun 24, 2026

Opens in a new windowTreasure Island Resort & Casino
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jun 28 to Jun 29
$131 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Room great and clean. Front desk staff extremely helpful and thorough"

Reviewed on Jun 23, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

3 out of 5
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $134 total per night from Jun 28 to Jun 29
$134 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The room was clean when we checked in, but housekeeping didn't come during our two-night visit. The beds were very comfortable. The kitchen in the bar was advertised open until 11:00pm, but it was closed when we went there before 10:00pm. The breakfast was good."

Reviewed on Jun 22, 2026

Opens in a new windowExpress Suites Riverport Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Jun 30 to Jul 1
$151 total
Jun 30 - Jul 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"It truly was a great experience."

Reviewed on Jun 24, 2026

Opens in a new windowKahler Grand Hotel
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jun 28 to Jun 29
$91 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
"This property is old and not really well maintained. The bathtub didn't drain well so you end up standing in ankle deep water. We chose this hotel because of the pool two days the hot tub was closed and another day the slide was closed."

Reviewed on Jun 24, 2026

Opens in a new windowBest Western Rochester Hotel Mayo Clinic Area/St. Mary's
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $88 total per night from Jul 12 to Jul 13
$88 total
Jul 12 - Jul 13
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"The room was neat and clean although the property less so. The location is near chain and ethnic restaurants and had a nice pub on the property which offered a discount. I would return because of price and location."

Reviewed on Jun 24, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jun 28 to Jun 29
$97 total
Jun 28 - Jun 29
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"Nice"

Reviewed on Jun 24, 2026

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 12 to Jul 13
$87 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The mattress on the bed was well used. A dip in the middle. 😏 The shower/tub in the bathroom was slippery when using the shower. My husband almost fell. There was no closet. However, it was quiet and the staff was very gracious. We will stay there again."

Reviewed on Jun 21, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Minnesota hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Minnesota hotel reviews by fellow wanderers

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