Book Hotels in Byron, MN
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Top Byron hotels

The Berkman
217 14th Ave SW, Rochester, MN
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $120 total per night from Oct 24 to Oct 25
$120 total
Oct 24 - Oct 25
Total with taxes and fees
This aparthotel features a gym and a seasonal outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a 24-hour business center, and ...
"Clean,quiet,professional."
Reviewed on Oct 18, 2025

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW, Suite A, Rochester, MN
Fully refundable
$111 nightly
The price is $127 total per night from Nov 7 to Nov 8
$127 total
Nov 7 - Nov 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Great stay! Looking forward to coming back next time we’re in the area!"
Reviewed on Oct 13, 2025

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Nov 2 to Nov 3
$81 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
"Staff is friendly, helpful, accommodating. Prices are reasonable."
Reviewed on Oct 13, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Oct 25 to Oct 26
$172 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Excellent service at the front desk! I had a tricky situation with a traveling companion and the lady working was so kind, patient, and professional. The hotel itself was clean and comfortable. I was traveling with 2 friends so we loved having the “living space” in our room plus the kitchen and island ..."
Reviewed on Oct 16, 2025

Hampton Inn Rochester-South
1755 S Broadway, Rochester, MN
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $93 total per night from Nov 14 to Nov 15
$93 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
"Room was clean, everyone was very nice and helpful"
Reviewed on Oct 16, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Fully refundable
$70 nightly
The price is $81 total per night from Nov 1 to Nov 2
$81 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Bathroom
"Bathroom doors could be different, there barn style doors. Not very much privacy. No breakfast offered."
Reviewed on Oct 17, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $135 total per night from Nov 1 to Nov 2
$135 total
Nov 1 - Nov 2
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Lots of construction in the area!"
Reviewed on Oct 16, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Oct 26 to Oct 27
$85 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Staff was very friendly and was a pleasure to talk to:)"
Reviewed on Oct 16, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Nov 18 to Nov 19
$136 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Nice hotel
"Kahler inn & suites is so conveniently close to Mayo. The rooms are clean and comfortable, and breakfast was great!"
Reviewed on Oct 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Byron hotel reviews by fellow wanderers

The Berkman
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Clean,quiet,professional."
A verified traveler stayed at The Berkman
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