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Top Byron hotels

Spark by Hilton Rochester South
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Jan 4 to Jan 5
$79 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
I did not have breakfast at the hotel.
Reviewed on Dec 15, 2025

Hampton Inn Rochester-South
1755 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $95 total per night from Jan 11 to Jan 12
$95 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
The hotel was very clean and so was our room. The staff at the front desk were extremely friendly and helpful.
Reviewed on Dec 15, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Dec 20 to Dec 21
$149 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Staff was very friendly. Rooms were nice. The only negative part of the stay was parking. The spots were small (ideal for compact only) and space was very limited. Due to both, we ended up taking Ubers everywhere.
Reviewed on Dec 11, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$80 nightly
The price is $92 total per night from Dec 25 to Dec 26
$92 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Overall great stay with clean roos
Reviewed on Dec 10, 2025

Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Dec 18 to Dec 19
$144 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
Good clean room every one helpful only thing for my wife and I it’s hard to keep the room cool for sleeping but that’s a small thing
Reviewed on Dec 7, 2025

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Dec 17 to Dec 18
$172 total
Dec 17 - Dec 18
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Room was clean, rooftop, pool, and sauna was a great spot to relax. The convenience of walking around underground in the winter to get to stores and restaurants is genius! Check out at noon too! Only issue was we have a large truck
Reviewed on Dec 11, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Dec 26 to Dec 27
$84 total
Dec 26 - Dec 27
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Room was clean but vacuuming hall at 1.30AM is out of ordinary.
Reviewed on Dec 14, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $153 total per night from Jan 10 to Jan 11
$153 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
We had a clean room, friendly staff and a large selection for breakfast.
Reviewed on Dec 15, 2025

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Dec 17 to Dec 18
$92 total
Dec 17 - Dec 18
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
Scrambled eggs, sausage, hard boiled eggs, fresh fruit, muffins, bagels nd more
Reviewed on Dec 12, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Byron with star-rating
Check Byron Hotels by Star Rating

4 Star Hotels
2 properties

3 Star Hotels
42 properties
Frequently asked questions
Recent Byron hotel reviews by fellow wanderers

Spark by Hilton Rochester South
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"I did not have breakfast at the hotel."
A verified traveler stayed at Spark by Hilton Rochester South
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