Book Hotels in Byron, MN

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Top Byron hotels

Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Jan 4 to Jan 5
$79 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
I did not have breakfast at the hotel.

Reviewed on Dec 15, 2025

Opens in a new windowSpark by Hilton Rochester South
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $95 total per night from Jan 11 to Jan 12
$95 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
The hotel was very clean and so was our room. The staff at the front desk were extremely friendly and helpful.

Reviewed on Dec 15, 2025

Opens in a new windowHampton Inn Rochester-South
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Dec 20 to Dec 21
$149 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Staff was very friendly. Rooms were nice. The only negative part of the stay was parking. The spots were small (ideal for compact only) and space was very limited. Due to both, we ended up taking Ubers everywhere.

Reviewed on Dec 11, 2025

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$80 nightly
The price is $92 total per night from Dec 25 to Dec 26
$92 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Overall great stay with clean roos

Reviewed on Dec 10, 2025

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Dec 18 to Dec 19
$144 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
Good clean room every one helpful only thing for my wife and I it’s hard to keep the room cool for sleeping but that’s a small thing

Reviewed on Dec 7, 2025

Opens in a new windowBrentwood Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Dec 17 to Dec 18
$172 total
Dec 17 - Dec 18
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Room was clean, rooftop, pool, and sauna was a great spot to relax. The convenience of walking around underground in the winter to get to stores and restaurants is genius! Check out at noon too! Only issue was we have a large truck

Reviewed on Dec 11, 2025

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Dec 26 to Dec 27
$84 total
Dec 26 - Dec 27
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Room was clean but vacuuming hall at 1.30AM is out of ordinary.

Reviewed on Dec 14, 2025

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $153 total per night from Jan 10 to Jan 11
$153 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
We had a clean room, friendly staff and a large selection for breakfast.

Reviewed on Dec 15, 2025

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Dec 17 to Dec 18
$92 total
Dec 17 - Dec 18
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
Scrambled eggs, sausage, hard boiled eggs, fresh fruit, muffins, bagels nd more

Reviewed on Dec 12, 2025

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Byron?
Take some of the worries out of traveling with youngsters by choosing a family-friendly hotel in Byron. From thoughtful amenities to services that bring a smile, these stays offer perks that'll help make your getaway run like a dream: Put your bags down at Luxury Custom Home in Golf Community. It comes with a fireplace, pet-friendly facilities and a flair for making families feel welcome. Also check out the deals at Rochesters Relaxing Ranch - 4 miles from Mayo. It comes with a king bed, free WiFi and ample opportunities for precious family time.
Where can I find cheap hotels in Byron?
At Travelocity you'll find really nice hotels in Byron at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Byron rather than in Byron. We may find you even better rates, too.
How do I find the best Byron hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Byron then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Byron?
The cheapest hotel in Byron is $79. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Byron?
There are 388 hotels in Byron on Travelocity.
What are the best hotels in Byron?
Byron has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Byron for you!
When is the best time to visit Byron?
If you want the joy of a fun-filled trip in peak season, visit Byron during March, May and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Byron?
Based on historic data is usually the cheapest month to visit Byron. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Byron?
There are multiple hotels in Byron that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Byron. We have plenty of kid-friendly hotels in Byron to choose from on Travelocity!
Why book a hotel in Byron through Travelocity?
Because we have the top hotels in Byron! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Byron on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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