Book a hotel near Mayo Park, Downtown Rochester

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Top hotels close to Mayo Park

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Free Cancellation
0.28 mi from Mayo Park
$69 nightly
The price is $79 total per night
$79 total
Dec 26 - Dec 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.
Pet friendly
Free WiFi
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3 out of 5
225 S Broadway Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.29 mi from Mayo Park
$107 nightly
The price is $123 total per night
$123 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi. There's a hot tub on site, and laundry facilities and free newspapers are also offered.
Pool
Hot Tub
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 out of 5
10 East Center Street Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.31 mi from Mayo Park
$171 nightly
The price is $197 total per night
$197 total
Dec 20 - Dec 21
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the 24-hour gym, bar/lounge, and laundry facilities.
Pool
Hot Tub
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

3.5 out of 5
101 1st Ave Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.36 mi from Mayo Park
$169 nightly
The price is $195 total per night
$195 total
Dec 12 - Dec 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and perks like a free shopping center shuttle.
Pool
Hot Tub
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.44 mi from Mayo Park
$149 nightly
The price is $172 total per night
$172 total
Dec 11 - Dec 12
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the hot tub, bar/lounge, and laundry facilities.
Pool
Hot Tub
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.53 mi from Mayo Park
$129 nightly
The price is $149 total per night
$149 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and an area shuttle.
Pool
Hot Tub
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.55 mi from Mayo Park
$155 nightly
The price is $178 total per night
$178 total
Dec 10 - Dec 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each morning.
Pool
Breakfast included
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
Free Cancellation
Reserve now, pay when you stay
0.59 mi from Mayo Park
$125 nightly
The price is $144 total per night
$144 total
Dec 10 - Dec 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business center. Self parking, laundry facilities, and free newspapers are also on offer.
Breakfast included
Free WiFi
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Free Cancellation
1.09 mi from Mayo Park
$111 nightly
The price is $127 total per night
$127 total
Dec 26 - Dec 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a 24-hour gym on site, and laundry facilities and barbecue grills are also offered.
Pool
Hot Tub
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Free Cancellation
Reserve now, pay when you stay
1.44 mi from Mayo Park
$72 nightly
The price is $83 total per night
$83 total
Dec 13 - Dec 14
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly dining. Enjoy a meal from the restaurant and perks like free full breakfast and free self parking.
Pool
Hot Tub
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Free Cancellation
Reserve now, pay when you stay
1.58 mi from Mayo Park
$73 nightly
The price is $84 total per night
$84 total
Dec 12 - Dec 13
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Enjoy the 24-hour gym and free perks like continental breakfast and free self parking.
Pool
Hot Tub
Hampton Inn Rochester-South

Hampton Inn Rochester-South

2.5 out of 5
1755 S Broadway Rochester MN
Free Cancellation
Reserve now, pay when you stay
1.78 mi from Mayo Park
$82 nightly
The price is $95 total per night
$95 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free area shuttle, 24-hour business center, and free WiFi in public areas.
Pool
Hot Tub
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mayo Park hotels essential information

Accommodation
427 hotels
Lowest Price
$79
Highest Price
$197
Popular hotels
Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area by IHG, Hyatt House Rochester/Mayo Clinic Area, Hampton Inn Rochester-South, Brentwood Inn & Suites, Hilton Garden Inn Rochester Downtown, MN, Med City Inn & Suites - Mayo Clinic Area, Hilton Rochester Mayo Clinic Area, EVEN Hotel Rochester - Mayo Clinic Area by IHG, Marriott Rochester Mayo Clinic, AmericInn by Wyndham Rochester Near Mayo Clinic

Recent Mayo Park hotel reviews by fellow wanderers

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

5 out of 5
Posted 17 hours ago
Travelocity Verified Review
"Clean room and great staff"
A verified traveler stayed at AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic

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