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Top St. Charles hotels

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$103 nightly
The price is $119 total per night from Sep 12 to Sep 13
$119 total
Sep 12 - Sep 13
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"This is my first time staying at Hotel Indigo. The staff was amazing. I had to keep adding nights and they were so accommodating. The room was just right. It was clean , well stocked and easy access to the Mayo Clinic. I really liked the front desk people. Super friendly and helpful. Love the attached ..."

Reviewed on Aug 23, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $124 total per night from Sep 3 to Sep 4
$124 total
Sep 3 - Sep 4
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Dirty at the pool. Ants on the floor. Room was not really clean."

Reviewed on Sep 1, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"The heat was not adjustable. Fan kept running"

Reviewed on Sep 1, 2026

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Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Sep 9 to Sep 10
$160 total
Sep 9 - Sep 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Breakfast was good and parking was a dood benefit"

Reviewed on Sep 1, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Sep 6 to Sep 7
$91 total
Sep 6 - Sep 7
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Here's a shorter version: --- **★☆☆☆☆ Disappointing stay — would not recommend** Stayed 3 nights (Aug 27–30) in two rooms at the Americana in Rochester. Rooms were not clean, and elevator carpets were dirty and smelly. Housekeeping after two days only did a towel service — no cleaning of the wash ..."

Reviewed on Sep 1, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$117 nightly
The price is $134 total per night from Sep 11 to Sep 12
$134 total
Sep 11 - Sep 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $114 total per night from Sep 20 to Sep 21
$114 total
Sep 20 - Sep 21
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
Opens in a new windowBest Western Rochester Hotel Mayo Clinic Area/St. Mary's
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Sep 2 to Sep 3
$82 total
Sep 2 - Sep 3
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

3 out of 5
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $134 total per night from Sep 2 to Sep 3
$134 total
Sep 2 - Sep 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowExpress Suites Riverport Inn & Suites
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See all available properties in St. Charles
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Charles Hotel & Travel Guide\n

There are less than a handful of hotels within a short drive of St. Charles. We recommend all visitors book early if you'd like to stay central.

The White Valley Motel is the closest accommodation to the center of St. Charles and the only Travelocity-listed hotel within a quick drive.

For those who are in the heart of St. Charles, it is around 13 miles (20 kilometers) to the Oakenwald Terrace.

Planning on seeing more of the forests and lakes this part of the country offers? How about you spend some extra nights in some of the other destinations in Southern Minnesota? Spend your time ice skating and quad biking or make a trip to the area's diverse places of interest. Suitable Travelocity-listed establishments will be your home away from home.

The closest hotels in Rochester are Austin and Austin. Austin is 50 miles (83 kilometers) to the southwest of St. Charles, while Austin is 50 miles (83 kilometers) to the southwest. Travelocity-registered hotel options in Austin include the Holiday Inn Austin and AmericInn Austin. The Days Inn Austin and Econo Lodge are some of the places to stay in Austin.

Make sure you spend a few hours hanging out with some Rochester lovers of sports at a community game. La Crosse Center is 40 miles (67 kilometers) to the east of St. Charles. Sports fans wanting to find hotels nearby can take their choice from the Courtyard by Marriott La Crosse or the Holiday Inn Hotel & Suites La Crosse.

If you're flying to St. Charles, a logical gateway is Rochester International Airport. The closest accommodation option is AmericInn Hotel & Suites Rochester Airport.

Frequently asked questions

What are the top kid-friendly hotels in St. Charles?
Take some of the worries out of traveling with little ones by opting for a family-friendly hotel in St. Charles. From useful amenities to extra-helpful services, these stays come with perks that'll make your getaway go off without a hitch: White Valley Motel will help make your getaway the best one yet. It offers plenty of conveniences geared toward families, such as pet-friendly facilities and front desk services. Alternatively, spend your nights enjoying the comforts of Below the Bluff | A Family Cabin Getaway in Lewiston, MN. Make the most of a king bed, animal viewing activities and more here.
Where can I find cheap hotels in St. Charles?
At Travelocity you'll find really nice hotels in St. Charles at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near St. Charles rather than in St. Charles. We may find you even better rates, too.
How do I find the best St. Charles hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in St. Charles then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in St. Charles?
The cheapest hotel in St. Charles is $82. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in St. Charles?
There are 492 hotels in St. Charles on Travelocity.
What are the best hotels in St. Charles?
St. Charles has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in St. Charles for you!
When is the best time to visit St. Charles?
If you want the joy of a fun-filled trip in peak season, visit St. Charles during March, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, February and November.
When is the cheapest time to stay in St. Charles?
Based on historic data is usually the cheapest month to visit St. Charles. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in St. Charles?
There are multiple hotels in St. Charles that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to St. Charles. We have plenty of kid-friendly hotels in St. Charles to choose from on Travelocity!
Why book a hotel in St. Charles through Travelocity?
Because we have the top hotels in St. Charles! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in St. Charles on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent St. Charles hotel reviews by fellow wanderers

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Staff here were very friendly and kind; our son was seen at Mayo Clinic and we were running late to do our check out but we called and asked if we could move it up to another hour and they were kind enough to say yes and that made this trip easier and stress free. Highly recommended!!"
A verified traveler stayed at Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area

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