Book a hotel near Mayo Clinic, Downtown Rochester
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Top hotels close to Mayo Clinic

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.08 mi from Mayo Clinic
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the hot tub, bar/lounge, and laundry facilities.
Pool
Hot Tub

Marriott Rochester Mayo Clinic
101 1st Ave Sw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.11 mi from Mayo Clinic
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and perks like a free shopping center shuttle.
Pool
Hot Tub

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.13 mi from Mayo Clinic
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each morning.
Pool
Breakfast included

Brentwood Inn & Suites
123 Fourth Ave. NW, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.19 mi from Mayo Clinic
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business center. Self parking, laundry facilities, and free newspapers are also on offer.
Breakfast included
Free WiFi

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Free Cancellation
0.21 mi from Mayo Clinic
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.
Pet friendly
Free WiFi

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.31 mi from Mayo Clinic
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and an area shuttle.
Pool
Hot Tub

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.38 mi from Mayo Clinic
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will appreciate the onsite laundry facilities. Enjoy the hot tub and free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Staybridge Suites Rochester - Mayo Clinic Area by IHG
101 11th Ave SW, Rochester, MN
Free Cancellation
0.61 mi from Mayo Clinic
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and an area shuttle.
Pool
Hot Tub

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW, Suite A, Rochester, MN
Free Cancellation
0.62 mi from Mayo Clinic
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and perks like a free area shuttle.
Pool
Hot Tub

Aspen Select
1215 2nd St SW, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.77 mi from Mayo Clinic
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour business center and free internet in public areas. There's a gym on site, and a 24-hour front desk and a terrace are also provided.
Breakfast included
Pet friendly

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
0.98 mi from Mayo Clinic
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly dining. Enjoy a meal from the restaurant and perks like free full breakfast and free self parking.
Pool
Hot Tub

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
1.6 mi from Mayo Clinic
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas and onsite conference space. Enjoy the 24-hour gym and free perks like continental breakfast and free self parking.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mayo Clinic hotels essential information
Accommodation | 415 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Kahler Grand Hotel, Hyatt House Rochester/Mayo Clinic Area, AmericInn by Wyndham Rochester Near Mayo Clinic, Kahler Inn and Suites - Mayo Clinic Area, EVEN Hotel Rochester - Mayo Clinic Area by IHG, Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area, Hotel Indigo Rochester – Mayo Clinic Area by IHG, Aspen Select, Brentwood Inn & Suites, Med City Inn & Suites - Mayo Clinic Area, Staybridge Suites Rochester - Mayo Clinic Area by IHG, Marriott Rochester Mayo Clinic |
Recent Mayo Clinic hotel reviews by fellow wanderers

Kahler Inn and Suites - Mayo Clinic Area
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Very nice staff, extremely convenient to Mayo , clean rooms"
A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area
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