Exclusive Mayo Clinic Vacation Deals

Mayo Clinic vacation package deals

Price found within the past 48 hours. Click for updated prices.
Quality Inn near Medical Center

Quality Inn near Medical Center

2.5 out of 5
Price was $521, price is now $389 per person
$389
per person
Feb 28 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Rochester (RST)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
Downtown Rochester
Save 100% on your flight
Price was $808, price is now $494 per person
$494
per person
Feb 28 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Rochester (RST)
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
Downtown Rochester
Price was $882, price is now $689 per person
$689
per person
Feb 28 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Rochester (RST)
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the hot tub, bar/lounge, and laundry facilities.
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
Downtown Rochester
Price was $847, price is now $663 per person
$663
per person
Feb 28 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Rochester (RST)
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each morning.
Aspen Suites

Aspen Suites

3 out of 5
Price was $887, price is now $697 per person
$697
per person
Feb 28 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Rochester (RST)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like full breakfast and free self parking.
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
Price was $539, price is now $428 per person
$428
per person
Feb 28 - Mar 7
found 1 day ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Rochester (RST)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks include continental breakfast, free self parking, and an area shuttle.

Frequently asked questions

How much are vacation packages to Mayo Clinic?
If you love the idea of stress-free planning and big savings, our $389 Mayo Clinic vacation package has got you covered. With your hotel and flights sorted, organizing your trip around this popular attraction is easier than ever.
Where can I get the best vacation package deals for Mayo Clinic?
Picking up a great package deal to Mayo Clinic couldn't be easier with Travelocity. With around 400 partner airlines and 1,000,000 properties across the globe, you won't be short of choice when it comes to your flights and hotels.
Why should I purchase my Mayo Clinic vacation package via Travelocity?
Travel is all about making cherished memories and leaving all your worries behind — which is why we have a team of experts available 24/7 should you need them. On top of that, our Price Match Guarantee ensures you'll always get the best price available on our impressive range of vacation destinations. So what are you waiting for? There's no time like the present to lock in the vacation of a lifetime.

Top Mayo Clinic hotel deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
$149 nightly
The price is $172 total per night
$172 total
Dec 26 - Dec 27
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the hot tub, bar/lounge, and laundry facilities.
Pool
Hot Tub
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Free Cancellation
Reserve now, pay when you stay
$155 nightly
The price is $178 total per night
$178 total
Dec 26 - Dec 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each morning.
Pool
Breakfast included
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Free Cancellation
$77 nightly
The price is $89 total per night
$89 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a rooftop terrace on site, and a 24-hour front desk and a snack bar/deli are also provided.
Pet friendly
Free WiFi
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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