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Top hotels in Downtown Rochester
TownePlace Suites by Marriott Rochester Mayo Clinic Area
601 2ND STREET SW, Rochester, MN
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $114 total per night from Oct 18 to Oct 19
$114 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Guests will appreciate freebies like buffet breakfast, WiFi in public areas, and an area shuttle. Self parking, ...
Nice hotel with good access to Mayo
"The room was nice, clean and quiet. It was well stocked with necessities. We had appointments at Mayo and was an easy walk to the Gonda Building. My only request would be that the fan on the heat/cool unit could run independently. It makes the perfect white noise whem trying to sleep on a strange ..."
Reviewed on Sep 24, 2025
Hilton Rochester Mayo Clinic Area
10 East Center Street, Rochester, MN
$186 nightly
The price is $214 total per night from Oct 24 to Oct 25
$214 total
Oct 24 - Oct 25
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"I enjoy this hotel"
Reviewed on Sep 15, 2025
Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Oct 3 to Oct 4
$160 total
Oct 3 - Oct 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"The hotel was clean and the room was clean. However, the couch had a definite smell of urine. It was very strong. It is a pet friendly hotel so I was assuming it was animal urine? It was bothersome, but I did not mention it to the hotel staff."
Reviewed on Sep 12, 2025
Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
$93 nightly
The price is $107 total per night from Oct 17 to Oct 18
$107 total
Oct 17 - Oct 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"For anyone visiting the Mayo Clinic this location is very convenient and easily accessible. Close to good restaurants including Crave right inside the hotel and the Italian restaurant Terza next door. I am usually picky about the quality of beds and cleanliness of the washroom. The bed was extremely ..."
Reviewed on Sep 18, 2025
Hilton Garden Inn Rochester Downtown, MN
225 S Broadway, Rochester, MN
$107 nightly
The price is $123 total per night from Oct 17 to Oct 18
$123 total
Oct 17 - Oct 18
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi. There's a hot tub on site, and laundry facilities ...
"Wonderful breakfast options and staff."
Reviewed on Sep 21, 2025
Brentwood Inn & Suites
123 Fourth Ave. NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Sep 28 to Sep 29
$144 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
"Great location hotel has direct access to Mayo Clinic subway system. Older property, but super clean with a great staff."
Reviewed on Sep 22, 2025
Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $147 total per night from Sep 29 to Sep 30
$147 total
Sep 29 - Sep 30
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Connected to the tunnel system with Mayo. Fantastic!"
Reviewed on Sep 22, 2025
Marriott Rochester Mayo Clinic
101 1st Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $264 total per night from Oct 3 to Oct 4
$264 total
Oct 3 - Oct 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"It was fine"
Reviewed on Aug 27, 2025
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $139 total per night from Oct 4 to Oct 5
$139 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Had appts at Mayo Clinic all week and was able to walk the underground subway to and from Mayo Clinic back to hotel room. The room was very clean and offered to clean room daily. Room had mini fridge and microwave. Ice machine down hall. Jimmy John’s right next door for easy food as we"
Reviewed on Sep 20, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Downtown Rochester Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Downtown Rochester area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown Rochester to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Downtown Rochester are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Downtown Rochester hotel reviews by fellow wanderers
TownePlace Suites by Marriott Rochester Mayo Clinic Area
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"The room was nice, clean and quiet. It was well stocked with necessities. We had appointments at Mayo and was an easy walk to the Gonda Building. My only request would be that the fan on the heat/cool unit could run independently. It makes the perfect white noise whem trying to sleep on a strange place."
A verified traveler stayed at TownePlace Suites by Marriott Rochester Mayo Clinic Area
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