Find and compare 3 Star hotels in Byron
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Byron 3 Star hotels
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $154 total per night from Aug 22 to Aug 23
$154 total
Aug 22 - Aug 23
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.4/10 Very Good! (2,277 reviews)
"The only problem was all the construction in the area"
Reviewed on Aug 20, 2026
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $118 total per night from Aug 22 to Aug 23
$118 total
Aug 22 - Aug 23
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
8.6/10 Excellent! (1,013 reviews)
"Great location for a visit to Mayo, within walking distance, which I would totally recommend rather than navigating a car in that craziness. The Twigs Bar and Restaurant were delicious and the outdoor patio was lovely."
Reviewed on Aug 20, 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$93 nightly
The price is $107 total per night from Sep 12 to Sep 13
$107 total
Sep 12 - Sep 13
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Aug 30 to Aug 31
$84 total
Aug 30 - Aug 31
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
8/10 Very Good! (1,437 reviews)
"The room was clean and very nice. Could use a little updating. We used the hot tub and definitely needs to be updated."
Reviewed on Aug 21, 2026
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Aug 30 to Aug 31
$87 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $166 total per night from Sep 18 to Sep 19
$166 total
Sep 18 - Sep 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Aspen Select
1215 2nd St SW Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Aug 22 to Aug 23
$151 total
Aug 22 - Aug 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Hilton Rochester Mayo Clinic Area
10 East Center Street Rochester MN
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $197 total per night from Aug 28 to Aug 29
$197 total
Aug 28 - Aug 29
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
470 17th Ave NW Rochester MN
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $128 total per night from Sep 3 to Sep 4
$128 total
Sep 3 - Sep 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the outdoor ...
9.6/10 Exceptional! (733 reviews)
"Great location if doctoring at St Mary’s. Good for visitors as it’s not right in the thick of construction. A/C unit was quite loud but otherwise a super clean and friendly place!"
Reviewed on Aug 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 Star Hotels Byron
Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.
You can find 3 star hotels in Byron that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.
When it comes to options, you’ll have them. The Byron 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.
Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Byron today!
Recent Byron hotel reviews by fellow wanderers
AmericInn by Wyndham Rochester Near Mayo Clinic
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"The room was clean and very nice. Could use a little updating. We used the hot tub and definitely needs to be updated."
A verified traveler stayed at AmericInn by Wyndham Rochester Near Mayo Clinic
More ways to wander Byron
Explore More Ways to Travel with Travelocity
- Bedandbreakfast in Rochester
- Hotels in Red Wing
- Hotels near Oxbow Park
- Hotels in Owatonna
- Hotels near Olmsted County Fairgrounds
- Hotels in Northfield
- Hotels near Mayo Clinic
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Hotels near Mayo Civic Center
- Hotels in Lake City
- Motels in Kasson
- Hotels in Kasson
- Pet Friendly in Kasson
- Aparthotels in Kasson
- Bedandbreakfast in Kasson
- Apartments in Kasson
- Downtown Rochester Hotels
- Hotels near Treasure Island Casino
- Hotels in Winona
- Hotels in Byron
- Apartments in Byron
- Hotels near Apache Mall
- 5 Star Hotels in Rochester
- 5 Star Hotels in Blooming Prairie
- 5 Star Hotels in Albert Lea
- 4 Star Hotels in Winona
- 4 Star Hotels in Rochester
- 4 Star Hotels in Historic Downtown Winona
- 3 Star Hotels in Albert Lea
- Agritourism in Southeast Minnesota
- Bedandbreakfast in Southeast Minnesota
- Cabins in Southeast Minnesota
- Condos in Southeast Minnesota
- Adults Only in Southeast Minnesota
- Casino in Southeast Minnesota
- Hotels near Rochester Recreation Center
- Kahler Inn and Suites - Mayo Clinic Area
- Kahler Grand Hotel
- Waterslide in Rochester
- Kitchenette in Rochester
- Indoor Pool in Rochester
- Hot Tub in Rochester
- Free Airport Transportation in Rochester
- Bar in Rochester
- Balcony in Rochester
- Pool in Rochester
- Hotel Indigo Rochester Mayo Clinic Area by IHG
- Med City Inn & Suites - Mayo Clinic Area
- Family Friendly in Rochester
- EVEN Hotel Rochester - Mayo Clinic Area by IHG
- Budget in Rochester
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- Brentwood Inn & Suites
- Boutique in Rochester
- The Berkman
- Aspen Select
- Aparthotels in Rochester
- Cabins in Rochester
- Hot Tub in Southeast Minnesota
- Lake in Southeast Minnesota
- Luxury in Southeast Minnesota
- Romantic in Southeast Minnesota
- Winery in Southeast Minnesota
- Motels in Rochester
- Hotels near Rochester MN
- Hotels in Rochester
- Waterpark in Rochester
- Spa in Rochester
- Romantic in Rochester
- Pet Friendly in Rochester
- Motel 6 Rochester MN
- Luxury in Rochester
- Flights from Louisville (SDF) to Rochester (RST)
- Flights from Reno (RNO) to Rochester (RST)
- Flights from Phoenix (PHX) to Rochester (RST)
- Flights from Chicago (ORD) to Rochester (RST)
- Flights from Middletown (MDT) to Rochester (RST)
- Flights from Orlando (MCO) to Rochester (RST)
- Flights from Kansas City (MCI) to Rochester (RST)
- Flights from Little Rock (LIT) to Rochester (RST)
- Flights from Grand Rapids (GRR) to Rochester (RST)
- Flights from Fairbanks (FAI) to Rochester (RST)
- Flights from Denver (DEN) to Rochester (RST)
- Flights from Nashville (BNA) to Rochester (RST)
- Flights from Latham (ALB) to Rochester (RST)
- United Airlines Sacramento (SMF) to Rochester (RST) flights
- Delta Air Lines Minneapolis (MSP) to Rochester (RST) flights
- Delta Air Lines Great Falls (GTF) to Rochester (RST) flights
- Delta Air Lines Denver (DEN) to Rochester (RST) flights
- American Airlines Evansville (EVV) to Rochester (RST) flights
- Flights from Rochester MN
- Flights to Rochester
- Hotels near Apache Mall
- Luxury Hotels in Rochester
- Car rentals in Rochester
- Flights to Rochester
- Hotels in Downtown Rochester
- Hotels near Mayo Clinic
- Hotels in Rochester
- Motels in Rochester
- Things to do in Southeast Minnesota
- Hotels in Kasson
- Cheap Hotels in Rochester
- Hotels near Mayo Clinic Hospital - Saint Marys Campus