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Top Byron 3 Star hotels

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Feb 19 to Feb 20
$146 total
Feb 19 - Feb 20
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.4/10 Very Good! (1,903 reviews)
Another great stay at the Kahler Grand Hotel. Its right across the street from the Mayo. Staff is excellent at the Kahler always very helpful.

Reviewed on Feb 18, 2026

Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Feb 19 to Feb 20
$152 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
8/10 Very Good! (1,521 reviews)
Very clean room. Nice breakfasts…

Reviewed on Feb 17, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Mar 1 to Mar 2
$86 total
Mar 1 - Mar 2
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
8.2/10 Very Good! (1,207 reviews)
Staff was friendly and the hotel/room were clean. Had a pool, kids pool and hot tub along with a spa. Had a restaurant onsite and offered continental breakfast, which had good options.

Reviewed on Feb 15, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Feb 24 to Feb 25
$79 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
9.4/10 Exceptional! (375 reviews)
Very clean and comfortable. The costumer service was outstanding.

Reviewed on Feb 13, 2026

Opens in a new windowSpark by Hilton Rochester South
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
$108 nightly
The price is $124 total per night from Feb 23 to Feb 24
$124 total
Feb 23 - Feb 24
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
8.6/10 Excellent! (1,005 reviews)
Room was nice, staff were exceptional.

Reviewed on Feb 15, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$95 nightly
The price is $110 total per night from Mar 5 to Mar 6
$110 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.8/10 Excellent! (936 reviews)
The room was clean, bed was comfortable, and location was great.

Reviewed on Feb 17, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3 out of 5
1125 2nd St Sw Rochester MN
$94 nightly
The price is $108 total per night from Mar 7 to Mar 8
$108 total
Mar 7 - Mar 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
8.6/10 Excellent! (962 reviews)
We left immediately. The room was not nice. The lighting was harsh, there was a bad smell in the hall and the beds were tiny. The room was so small!

Reviewed on Feb 2, 2026

Opens in a new windowSpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $81 total per night from Feb 20 to Feb 21
$81 total
Feb 20 - Feb 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
7.2/10 Good! (1,039 reviews)
NICE

Reviewed on Feb 17, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Feb 21 to Feb 22
$151 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
9/10 Wonderful! (1,002 reviews)
Very nice staff rooms were great

Reviewed on Feb 16, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

3.5 out of 5
101 1st Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $229 total per night from Feb 20 to Feb 21
$229 total
Feb 20 - Feb 21
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
8.4/10 Very Good! (537 reviews)
Front desk not seem hospitable or interested in our arriving. Don’t like absence of rugs. First only one chair; we both like to read and 2nd room did after requested change. Cafe has no ambiance; not look like fun place to eat. We ate elsewhere both nights.

Reviewed on Feb 18, 2026

Opens in a new windowMarriott Rochester Mayo Clinic
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3 Star Hotels Byron

Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.

You can find 3 star hotels in Byron that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.

When it comes to options, you’ll have them. The Byron 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.

Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Byron today!

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