Explore top 2025 4 Star Hotels in Byron

Name: The Towers At Kahler Grand Hotel
Rating: 9.4

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Top Byron 4 Star hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG

101 11TH Avenue SW, Suite A, Rochester, MN

Fully refundable

$121 nightly

$139 total

Oct 11 - Oct 12

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.4/10 Exceptional! (901 reviews)

Fine for the basics.

"All the basics are there. Nothing special, certainly not luxurious, but comfortable enough. About a 15-minute walk to Mayo. Few stores or restaurants close by."

Reviewed on Sep 25, 2025

The Towers At Kahler Grand Hotel

20 2nd Ave SW, Rochester, MN

This smoke-free hotel includes 2 restaurants, an indoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.4/10 Exceptional! (87 reviews)

"Good breakfast and Ruth Chris steakhouse on property was great. Very comfortable quiet and clean room. Shane and David were fantastic and hospitable. Easiest access to Mayo Clinic. Loved that it was also a historical hotel."

Reviewed on Aug 1, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Byron

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Byron 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Byron will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Byron, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.