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Top Mazeppa hotels

Hyatt House Rochester/Mayo Clinic Area
"This is a hotel that due to its proximity to Mayo Clinic has a unique clientele and everyone there is so kind and considerate and extremely helpful. I highly recommend this property. The pool/hot tub setup is very pleasant after a long day at the hospital. It’s also very safe and accessible."
Reviewed on Nov 15, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
"Service great"
Reviewed on Nov 15, 2026

Kahler Grand Hotel
"The staff was totally useless because we booked with Expedia. I booked my trip far in advance but still was"
Reviewed on Nov 15, 2026

Med City Inn & Suites - Mayo Clinic Area

AmericInn by Wyndham Rochester Near Mayo Clinic

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

Brentwood Inn & Suites

The Berkman
Mazeppa Hotel & Travel Guide\n
Are you looking to spend a few nights in Mazeppa? You will probably find it a bit difficult to book a base for your trip in the town's center, however, by expanding your search a bit further out you'll discover a good array of hotels and accommodations. Appreciate the scenery on the ride into Mazeppa, leaving from any of the 39 lodgings scattered around a 19-mile (30-kilometer) distance.
The closest of our hotels is the Marriott Rochester Mayo Clinic, Minnesota, which lies 18 miles (29 kilometers) from the downtown area of Mazeppa. A second handy Travelocity accommodation option is the Residence Inn by Marriott Rochester Mayo Clinic Area, found in Minnesota, about 18 miles (28 kilometers) from the middle of Mazeppa.
You could also check out the DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area and the Aspen Suites. The DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area is located only 18 miles (29 kilometers) away from the city center of Mazeppa. The Aspen Suites, is just 18 miles (28 kilometers) away. You could also book the Hilton Garden Inn Rochester Downtown, MN or the Holiday Inn Express & Suites Rochester West Medical Center.
How about you explore some more of the forests that are common in Southern Minnesota? Plan to spend a bit of time in some of the other fascinating areas of Southern Minnesota. Take part in ice skating and quad biking or explore the district's local sights. A range of hotel options are on offer.
The nearest places to spend the night in Rochester are Austin and Austin. Austin is 45 miles (75 kilometers) to the southwest of Mazeppa, while Austin is 45 miles (75 kilometers) to the southwest. Austin Travelocity-listed bases are the Holiday Inn Austin and AmericInn Austin. The Days Inn Austin and Econo Lodge are amongst the lodgings in Austin.
Before you head home from Rochester, make sure you get down to watch an exciting game. Get to Xcel Energy Center, which you can find northwest of Mazeppa. Sleep right in the thick of the action at the The Saint Paul Hotel or the Holiday Inn St. Paul Downtown.
Are you keen to find the most practical airport for Mazeppa? Rochester International Airport is situated 25 miles (41 kilometers) away.
Frequently asked questions
Recent Mazeppa hotel reviews by fellow wanderers

Hotel Indigo Rochester – Mayo Clinic Area by IHG
"Service great"
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