Book Hotels in Santa Isabel

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santa Isabel hotels

Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
$146 nightly
The price is $160 total per night from Aug 6 to Aug 7
$160 total
Aug 6 - Aug 7
Total includes taxes and fees
An outdoor pool is featured at this hotel, along with a virtual front desk. Take advantage of the free self parking.
"Is a beautiful place and the staff Rosie is a plus."

Reviewed on Jul 12, 2025

Hacienda del Sur
Modern Cozy Home in Puerto Rican Paradise

Modern Cozy Home in Puerto Rican Paradise

Santa Isabel
Stay at this vacation home in Santa Isabel. Enjoy free WiFi, a water park, and an in-room coffeemaker. Popular attractions Carribbean Cinemas Santa Isabel and ...
Amazing stay
"This place was great and got the job done! Clarissa was not only super helpful but she was very accommodating and easy to contact. If we ever are back on that side of the island we will definitely be staying here again."

Reviewed on Apr 10, 2025

Get rates
Modern Cozy Home in Puerto Rican Paradise
Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

Santa Isabel
$343 nightly
The price is $364 total per night from Jul 27 to Jul 28
$364 total
Jul 27 - Jul 28
Total includes taxes and fees
A hot tub is featured at this vacation home, along with laundry facilities and concierge services. Barbecue grills are provided for your convenience.
Loved
"It was amazing to be in the center of the culture. Friendly neighbors! Food amazing! Beach’s all around I would definitely stay there again!!!"

Reviewed on Jun 15, 2025

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Hilton Ponce Golf & Casino Resort

Hilton Ponce Golf & Casino Resort

4.5 out of 5
1150 Caribe Avenue, Ponce
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $203 total per night from Jul 31 to Aug 1
$203 total
Jul 31 - Aug 1
Total includes taxes and fees
This luxury resort features a golf course, free water park access, and a casino. Bring the family and enjoy the mini golf, children's pool, and waterslide. Enjoy ...
"I love it"

Reviewed on Jul 14, 2025

Hilton Ponce Golf & Casino Resort
Aloft Ponce Hotel & Casino

Aloft Ponce Hotel & Casino

3.5 out of 5
Street No 2 KM 228.9, Ponce
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $199 total per night from Aug 4 to Aug 5
$199 total
Aug 4 - Aug 5
Total includes taxes and fees
A casino, 4 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Guests will appreciate free perks like free self parking and WiFi in ...
"The hotel is at a convenient location close to the highway. I have stayed here before and notice the property is lacking proper maintenance. Some outlets in my room were loose. They would nearly come out if you tried to plug something in. I had a situation with the toilet not flushing. Our towels ..."

Reviewed on Jul 15, 2025

Aloft Ponce Hotel & Casino
Holiday Inn Ponce & Tropical Casino by IHG

Holiday Inn Ponce & Tropical Casino by IHG

3.5 out of 5
3315 Ponce By Pass, Ponce
Fully refundable
$152 nightly
The price is $169 total per night from Aug 6 to Aug 7
$169 total
Aug 6 - Aug 7
Total includes taxes and fees
A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. A restaurant and a bar/lounge ...
"Beatiful view"

Reviewed on Jul 21, 2025

Holiday Inn Ponce & Tropical Casino by IHG
Caribe Hotel Ponce

Caribe Hotel Ponce

3.5 out of 5
103 Turpo Industrial Park, Ponce
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $162 total per night from Jul 27 to Jul 28
$162 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self ...
"Nos encanto la piscina y la comodidad del cuarto. No me gusto que nuestra habitacion no tenia microondas. Lo demas todo excelente"

Reviewed on Jul 23, 2025

Caribe Hotel Ponce
Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
$92 nightly
The price is $100 total per night from Jul 30 to Jul 31
$100 total
Jul 30 - Jul 31
Total includes taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
"It was a nice getaway"

Reviewed on Jun 25, 2025

Hotel Las Vegas
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

Santa Isabel
This vacation home featured laundry facilities and barbecue grills.
Unforgettable Family Vacation at Mimi’s Stunning VRBO!
"Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to ..."

Reviewed on Jun 2, 2025

Get rates
Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL
Don't see what you're looking for?
See all available properties in Santa Isabel
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Isabel?
Book a stay at Beautiful Unique and Peaceful Farm Wood Cabin and make vacationing with the youngsters super simple. This popular option in Santa Isabel offers amenities designed to make family trips easier, such as a swimming pool.
Where can I find cheap hotels in Santa Isabel?
At Travelocity you'll find really nice hotels in Santa Isabel at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Isabel rather than in Santa Isabel. We may find you even better rates, too.
How do I find the best Santa Isabel hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Isabel then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Isabel?
The cheapest hotel in Santa Isabel is $100. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Isabel?
There are 272 hotels in Santa Isabel on Travelocity.
What are the best hotels in Santa Isabel?
Santa Isabel has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Isabel for you!
When is the best time to visit Santa Isabel?
If you want the joy of a fun-filled trip in peak season, visit Santa Isabel during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Isabel?
Based on historic data is usually the cheapest month to visit Santa Isabel. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Isabel?
There are multiple hotels in Santa Isabel that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Isabel. We have plenty of kid-friendly hotels in Santa Isabel to choose from on Travelocity!
Why book a hotel in Santa Isabel through Travelocity?
Because we have the top hotels in Santa Isabel! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Isabel on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Isabel hotel reviews by fellow wanderers

Caribe Hotel Ponce

Caribe Hotel Ponce

5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"Nos encanto la piscina y la comodidad del cuarto. No me gusto que nuestra habitacion no tenia microondas. Lo demas todo excelente"
A verified traveler stayed at Caribe Hotel Ponce
Caribe Hotel Ponce
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity