Book Hotels in Santa Isabel
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Santa Isabel hotels

Hacienda del Sur
Carr 545 KM 1.5, Sector Gabia Santa Isabel
$132 nightly
The price is $144 total per night from Apr 15 to Apr 16
$144 total
Apr 15 - Apr 16
Total with taxes and fees
An outdoor pool, free self parking, and a virtual front desk are featured at this hotel. A garden is also provided.
Excelente lugar, limpio, comodo, excelente localizacion
Reviewed on Apr 5, 2026

3BR Puerto Rico Villa w Pool | Aqua Bella 1
Santa Isabel PR
This vacation home includes a garden and barbecue grills.
It is a very small house it really should not be marketed for more than 4 people the single seat bed is not good for an adult. Once you open de sofa bed there is no space to socialize inside the house. Having a beach front property with a pool and not provide beach towels is not convenient at all. ...
Reviewed on Jan 4, 2026

Ponce Plaza Hotel & Casino
Reina Street Ponce
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $180 total per night from May 3 to May 4
$180 total
May 3 - May 4
Total with taxes and fees
A casino and an outdoor pool are featured at this smoke-free hotel. Enjoy the gym and perks like free WiFi. Self parking, a coffee shop, and a library are also ...
Excelente ubicación
Reviewed on Apr 12, 2026

Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep
Santa Isabel
$339 nightly
The price is $360 total per night from Apr 14 to Apr 15
$360 total
Apr 14 - Apr 15
Total with taxes and fees
Laundry facilities, concierge services, and barbecue grills are available at this vacation home.
Very nice,on the ocean,steps to beach need repair
Reviewed on Mar 12, 2026

Hilton Ponce Golf & Casino Resort
1150 Caribe Avenue Ponce
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $246 total per night from Apr 17 to Apr 18
$246 total
Apr 17 - Apr 18
Total with taxes and fees
This luxury resort features a golf course, free water park access, and a casino. Bring the family and enjoy the mini golf, children's pool, and waterslide. Enjoy ...
Excellent Place to stay and enjoy.
Reviewed on Apr 11, 2026

Gorgeous Place with Pool and Patio
Santa Isabel Santa Isabel
$235 nightly
The price is $250 total per night from Apr 14 to Apr 15
$250 total
Apr 14 - Apr 15
Total with taxes and fees
An outdoor pool is featured at this bed & breakfast, along with barbecue grills.
Family getaway
Maria was great! She was very responsive when we needed something. She also communicated with us when there was going to be cleaning done in the pool. Overall the place was clean. The pool was amazing and it was great that we had it all to ourselves.
Reviewed on Apr 26, 2021

Hotel Las Vegas
PR 153, Km 2.9 Santa Isabel
$78 nightly
The price is $85 total per night from Apr 21 to Apr 22
$85 total
Apr 21 - Apr 22
Total with taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock.
The location of the hotel is in a very local spot
Reviewed on Apr 3, 2026

Beachfront Bliss: Spacious 5-Bedroom, 2-Bath Escape with Stunning Ocean Views
santa isabel puerto rico
Stay at this villa in Santa Isabel. Enjoy patios and air conditioning. Popular attractions Playa La Ochenta and Marina de Salinas are located nearby.
Host never contacted us we found the house on our own absolute dump , didn’t stay went somewhere else
Reviewed on Feb 13, 2026

Romantic 1BR Puerto Rico Villa w Pool|Aqua Bella 2
Santa Isabel PR
$553 nightly
The price is $587 total per night from May 12 to May 13
$587 total
May 12 - May 13
Total with taxes and fees
This villa includes a garden and barbecue grills.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Santa Isabel hotel reviews by fellow wanderers

Ponce Plaza Hotel & Casino
4 out of 5
Posted 15 hours ago
Travelocity Verified Review
"Excelente ubicación"
A verified traveler stayed at Ponce Plaza Hotel & Casino
Explore More Ways to Travel with Travelocity
- Hotels near El Vigia Hill
- 3 Star Hotels in Isla Caja de Muertos
- Apartments in Isla Caja de Muertos
- Isla Caja de Muertos Hotels
- Vacation Homes in Isla Caja de Muertos
- Resorts in Isla Caja de Muertos
- Villas in Isla Caja de Muertos
- Hotels near San Cristobal Canyon
- Central Aguirre Hotels
- Asomante Hotels
- Jauca I Hotels
- Hotels near Cardona Island Light
- Primero Hotels
- Hotels near Reserva Nacional de Investigación Estuarina de Bahía de Jobos
- Ponce Centro Hotels
- Hotels near Toro Negro State Forest
- Apartments in Juana Diaz
- Extended Stay Hotels in Juana Diaz
- Juana Diaz Hotels
- Motels in Juana Diaz
- Vacation Homes in Juana Diaz
- Villas in Juana Diaz
- Coamo Hotels
- Motels in Coamo
- Orocovis Hotels
- Barranquitas Hotels
- Caonillas Arriba Hotels
- Hotels near Mercedita
- Llanos Hotels
- Hotels near El Museo Castillo Serralles
- Aibonito Hotels
- Coto Laurel Hotels
- Apartments in Salinas
- B&B in Salinas
- Extended Stay Hotels in Salinas
- Salinas Hotels
- Playa Hotels
- Plata Hotels
- Cuarto Hotels
- Villalba Hotels
- Hotels near Marina de Salinas
- Hotels near Albergue Olimpico
- Hotels near La Guancha
- Ponce Hotels
- Flights to Isla Caja de Muertos
- Flights from Chicago to Isla Caja de Muertos
- Flights to Juana Diaz
- Flights from Mercedita
- Jetblue Airways Baltimore (BWI) to Ponce (PSE) flights
- Jetblue Airways Hartford (BDL) to Ponce (PSE) flights
- Jetblue Airways Charlotte (CLT) to Ponce (PSE) flights
- Jetblue Airways Fort Lauderdale (FLL) to Ponce (PSE) flights
- Jetblue Airways Houston (IAH) to Ponce (PSE) flights
- Jetblue Airways Rochester (ROC) to Ponce (PSE) flights
- Jetblue Airways Syracuse (SYR) to Ponce (PSE) flights
- Jetblue Airways Jacksonville (JAX) to Ponce (PSE) flights
- Jetblue Airways New York (JFK) to Ponce (PSE) flights
- Jetblue Airways New York (LGA) to Ponce (PSE) flights
- Jetblue Airways Boston (BOS) to Ponce (PSE) flights
- Jetblue Airways Miami (MIA) to Ponce (PSE) flights
- Jetblue Airways Newark Liberty Intl. Airport (EWR) to Ponce (PSE) flights
- Jetblue Airways Chicago (ORD) to Ponce (PSE) flights
- Jetblue Airways Orlando (MCO) to Ponce (PSE) flights
- Jetblue Airways Philadelphia (PHL) to Ponce (PSE) flights
- Jetblue Airways Raleigh (RDU) to Ponce (PSE) flights
- Jetblue Airways San Antonio (SAT) to Ponce (PSE) flights
- Jetblue Airways Phoenix (PHX) to Ponce (PSE) flights
- Jetblue Airways Fort Myers (RSW) to Ponce (PSE) flights
- Jetblue Airways Tampa (TPA) to Ponce (PSE) flights
- Jetblue Airways Providence (PVD) to Ponce (PSE) flights
- Spirit Airlines Orlando (MCO) to Ponce (PSE) flights
- Flights from Atlanta (ATL) to Ponce (PSE)
- Flights from Hartford (BDL) to Ponce (PSE)
- Flights from Cleveland (CLE) to Ponce (PSE)
- Flights from Dallas (DFW) to Ponce (PSE)
- Flights from Newark Liberty Intl. Airport (EWR) to Ponce (PSE)
- Flights from Fort Lauderdale (FLL) to Ponce (PSE)
- Flights from New York (JFK) to Ponce (PSE)
- Flights from Orlando (MCO) to Ponce (PSE)
- Flights from Philadelphia (PHL) to Ponce (PSE)
- Flights from Raleigh (RDU) to Ponce (PSE)
- Flights from Tampa (TPA) to Ponce (PSE)
- Flights to Salinas
- Car rentals near Isla Caja de Muertos
- Car rental Juana Diaz
- Luxury Car Rentals in Juana Diaz
- Car rental Coamo
- Alamo Rent A Car Rental Cars in Mercedita
- Rental cars Mercedita airport
- Dollar Rent A Car Rental Cars in Mercedita
- Hertz Rental Cars in Mercedita
- Car rental Salinas
- Convertible Car Rentals in Salinas
- Van Car Rentals in Salinas






