Book Hotels in Des Peres, MO

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Jun 5 - Jun 7
Next weekend
Jun 12 - Jun 14

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Des Peres hotels

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $179 total per night from Jun 9 to Jun 10
$179 total
Jun 9 - Jun 10
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
"Check in was easy and very informative. Our was clean, Kick back time was great and breakfast was a full buffet."

Reviewed on Jun 4, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Jun 14 to Jun 15
$106 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Room was clean but very small"

Reviewed on Jun 3, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $189 total per night from Jun 21 to Jun 22
$189 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Went to St Louis to watch a couple of Cardinals Games. And excellent location to say the least. Staff was fantastic and very helpful. Also had room service for breakfast. Food was very good and an excellent value as well. Well return soon!"

Reviewed on Jun 4, 2026

Opens in a new windowLive by Loews - St.Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Jun 14 to Jun 15
$115 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Clean room and friendly staff."

Reviewed on Jun 5, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jun 9 to Jun 10
$143 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Has always been a good place to stay when we go to st louis for a couple of ball games. Clean, comfortable and friendly, helpful staff. Great location, convenient to Busch stadium and central city area."

Reviewed on Jun 4, 2026

Opens in a new windowPear Tree Inn St. Louis Near Union Station
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

3.5 out of 5
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jun 11 to Jun 12
$143 total
Jun 11 - Jun 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"It was an above average stay, the hotel was maintained. The pool was cold, great for summer. Breakfast was excellent and the staff for breakfast also great! No loyalty points were allowed as we had booked through an alternate booking site. That was disappointing. Overall we would stay again."

Reviewed on Jun 3, 2026

Opens in a new windowHampton Inn St. Louis-Downtown (At the Gateway Arch)
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Jun 12 to Jun 13
$162 total
Jun 12 - Jun 13
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
"The property was very clean. The staff was helpful. I liked after we watched the baseball game, walking back to the hotel and sitting at the bar for a drink. That was very nice. A good night Sleep we’re very pleased."

Reviewed on Jun 5, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $136 total per night from Jun 7 to Jun 8
$136 total
Jun 7 - Jun 8
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
"Amazing!"

Reviewed on Jun 4, 2026

Opens in a new windowHollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $115 total per night from Jun 7 to Jun 8
$115 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Our room was clean and modern, the location was great for our weekend activity, and the breakfast was great. We would stay here again."

Reviewed on Jun 4, 2026

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Don't see what you're looking for?
See all available properties in Des Peres
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Peres Hotel & Travel Guide\n

Want to explore St. Louis? Looking to find a place to relax? Travelocity features a wide range of options. Travelocity's user-friendly booking portal at present contains 18 hotels within a short drive of Des Peres.

Travelocity-listed accommodation options that are close to the town center of Des Peres include the Hampton Inn St. Louis/Sunset Hills and Hilton St. Louis Frontenac.

The Four Seasons Hotel St Louis is around 14 miles (23 kilometers) from the middle of Des Peres. On the other hand, the The Ritz-Carlton, St. Louis is located 7 miles (12 kilometers) away. Some other possible Travelocity-listed accommodation options include the Grand Center Inn and the Ameristar Casino Resort and Spa.

Looking to move out of the center? St. Louis - Northeast Missouri offers many impressive attractions worth checking out. If you love nature, get ready to discover St. Louis - Northeast Missouri's prairies. You should also wind your way through the area's history museums. Common activities in this area of United States of America include mountain biking and hiking.

You could spend some time exploring The Gardens at SIUE and Edwardsville Arts Center, which can be found in North MetroEast, 25 miles (41 kilometers) to the northeast of Des Peres. Should you wish to stay in North MetroEast, be sure to check out the Hampton Inn Suites St LouisEdwardsville and Comfort Inn and Conference Center. 13 miles (21 kilometers) east of Des Peres, you'll find Downtown St. Louis, which features the The Westin St. Louis and Embassy Suites St. Louis - Downtown. Whether you're just passing through or staying in Downtown St. Louis, you might like to visit the Old Post Office and Scott Joplin House State Historic Site.

Simply because you and your traveling partners are on a break, does not mean that you can't fuel your love for all things sport. Busch Stadium is 14 miles (22 kilometers) to the east of Des Peres. Modern travelers that want to find accommodation in the area surrounding the stadium should choose between the Residence Inn by Marriott St Louis Downtown or the Hilton St. Louis at the Ballpark.

For the modern traveler traveling via Lambert-St. Louis International Airport, you may plan to book some accommodation at Marriott St. Louis Airport, or Holiday Inn St. Louis-Airport, which are both nearby.

Frequently asked questions

What are the top kid-friendly hotels in Des Peres?
Take some of the worries out of traveling with youngsters by choosing a family-friendly Des Peres hotel. From entertaining amenities to additional services, these properties feature perks that'll make your trip run like a dream: You'll be well looked after at Special Mar pricing! ~Great location book now~ T. It comes with internet access, clothes washing facilities and a flair for making families feel welcome. Monthly Stays Luxe Des Peres Suite with Complimentary Starbucks Onsite! is another top place to stay. After a fun day of exploring, come back home to your comfortable room and amenities like a swimming pool and free WiFi.
Where can I find cheap hotels in Des Peres?
At Travelocity you'll find really nice hotels in Des Peres at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Des Peres rather than in Des Peres. We may find you even better rates, too.
How do I find the best Des Peres hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Des Peres then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Des Peres?
The cheapest hotel in Des Peres is $106. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Des Peres?
There are 1,895 hotels in Des Peres on Travelocity.
What are the best hotels in Des Peres?
Des Peres has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Des Peres for you!
When is the best time to visit Des Peres?
If you want the joy of a fun-filled trip in peak season, visit Des Peres during March, May and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, October and December.
When is the cheapest time to stay in Des Peres?
Based on historic data is usually the cheapest month to visit Des Peres. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Des Peres?
There are multiple hotels in Des Peres that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Des Peres. We have plenty of kid-friendly hotels in Des Peres to choose from on Travelocity!
Why book a hotel in Des Peres through Travelocity?
Because we have the top hotels in Des Peres! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Des Peres on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Des Peres hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"The property was very clean. The staff was helpful. I liked after we watched the baseball game, walking back to the hotel and sitting at the bar for a drink. That was very nice. A good night Sleep we’re very pleased."
A verified traveler stayed at Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch

Explore More Ways to Travel with Travelocity